Abstract
Hydroxyapatite [HAp, Ca5(PO4)3(OH)] was synthesized by chemical precipitation, using H3PO4 and Ca(OH)2 as chemical precursors. The precursors were slowly mixed in suitable proportions aiming to obtain Ca/P molar ratios of 1.5, 1.67 or 2.0 in the reacting suspension. This was followed by 21.5 h of aging. Both reaction and aging stages were carried out under an atmosphere of still ambient air and under continuous stirring, either at room temperature, 60 or 90 ºC. The precipitates were characterized by ICP-AES and XRD. The results suggested that the most suitable Ca/P molar ratio for the production of pure phase HAp is Ca/P = 1.67, as long as the initial Ca(OH)2 particle size and/or the suspension pH are carefully controlled, especially when the synthesis is carried out above room temperature.
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López-Cuevas, J., Rendón-Angeles, J.C., Rodríguez-Galicia, J.L. et al. Effect of Experimental Conditions on the Chemical Composition of Hydroxyapatite Synthesized by Chemical Precipitation. MRS Advances 2, 3851–3857 (2017). https://doi.org/10.1557/adv.2018.105
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DOI: https://doi.org/10.1557/adv.2018.105