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Analysis of Changes in the Structure of DNA when Interacting with Platinum Coordination Compounds by IR Spectroscopy

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Abstract—A systematic assignment of bands observed in the range of 1800–800–1 cm when measuring samples in KBr pellets based on the example of the analysis of infrared spectra of DNA complexes with dichlorodiammineplatinum(II) was performed. Based on the performed decomposition of the spectra of DNA and its complexes with dichlorodiammineplatinum(II), it was shown that the results are in good agreement with the direct structural data, as well as with previous measurements in solution. It was also shown that markers of the A- and B-forms of DNA are simultaneously observed in the DNA spectra in KBr pellets.

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REFERENCES

  1. A. M. Polyanichko, N. M. Romanov, T. Y. Starkova, et al., Cell Tissue Biol. 8 (4), 352 (2014).

    Article  Google Scholar 

  2. A. M. Polyanichko, V. V. Andrushchenko, P. Bouř, et al., in Circular Dichroism: Theory and Spectroscopy, Ed. by D. S. Rodgers (Nova Science Publ., New York, 2012), pp. 67–126.

    Google Scholar 

  3. A. M. Polyanichko and H. Wieser, in Methods in Protein Structure and Stability Analysis: Vibrational Spectroscopy, Ed. by E. Permyakov and V. Uversky (Nova Science Publ., New York, 2007), pp. 267–302.

    Google Scholar 

  4. A. Polyanichko and H. Wieser, Biopolymers 78 (6), 329 (2005).

    Article  Google Scholar 

  5. P. C. Gros and M. Zeppezauer, J. Pharm. Biomed. Anal. 53 (1), 29 (2010).

    Article  Google Scholar 

  6. M. J. Baker, J. Trevisan, P. Basson, et al., Nat. Protoc. 9 (8), 1771 (2014).

    Article  Google Scholar 

  7. Y. Han, L. Han, Y. Yao, et al., Anal. Methods 10 (21), 2436 (2018).

    Article  Google Scholar 

  8. G. P. Zhizhina and E. F. Oleinik, Usp. Khim. 41 (3), 474 (1972).

    Article  Google Scholar 

  9. M. Tsuboi, Appl. Spectrosc. Rev. 3 (1), 45 (1970).

    Article  ADS  Google Scholar 

  10. R. Stefan, C. M. Muntean, C. Tripon, et al., Polym. Degrad. Stab. 108, 35 (2014).

    Article  Google Scholar 

  11. P. J. Gomes, P. A. Ribeiro, D. Shaw, et al., Polym. Degrad. Stab. 94 (12), 2134 (2009).

    Article  Google Scholar 

  12. H. A. Tajmir-Riahi, C. N. N’Soukpoé-Kossi, and D. Joly, Spectroscopy 23 (2), 81 (2009).

    Article  Google Scholar 

  13. S. E. Sherman and S. J. Lippard, Chem. Rev. 87 (5), 1153 (1987).

    Article  Google Scholar 

  14. I. A. G. Roos, A. J. Thomson, and S. Mansy, J. Am. Chem. Soc. 96 (20), 6484 (1974).

    Article  Google Scholar 

  15. E. R. Jamieson and S. J. Lippard, Chem. Rev. 99 (9), 2467 (1999).

    Article  Google Scholar 

  16. S. Mansy, B. Rosenberg, and A. J. Thomson, J. Am. Chem. Soc. 95 (5), 1633 (1973).

    Article  Google Scholar 

  17. E. Wong and C. M. Giandomenico, Chem. Rev. 99 (9), (1999).

  18. L. Kelland, Nat. Rev. Cancer 7 (8), 573 (2007).

    Article  Google Scholar 

  19. A. M. Polyanichko, V. Andrushchenko, E. V. Chikhirzhina, et al., Nucleic Acids Res. 32 (3), 989 (2004).

    Article  Google Scholar 

  20. A. S. Spirin, Biokhimiya 23 (5), 656 (1958).

    Google Scholar 

  21. I. Belaya, E. Chikhirzhina, and A. Polyanichko, J. Mol. Struct. 1140, 148 (2017).

    Article  ADS  Google Scholar 

  22. L. Plotnikova, M. Kobeleva, E. Borisov, et al., Cell Tissue Biol. 13 (2), 130 (2019).

    Article  Google Scholar 

  23. J. A. Taboury, J. Liquier, and E. Taillandier, Can. J. Chem. 63 (7), 1904 (1985).

    Article  Google Scholar 

  24. H. Taniguchi and M. Saito, J. Phys. Condens. Matter 21 (6), 064242 (2009).

    Article  ADS  Google Scholar 

  25. A. Pevsner and M. A. X. Diem, Appl. Spectrosc. 55 (11), 1502 (2001).

    Article  ADS  Google Scholar 

  26. C. Escude, S. Mohammadi, J. Sun, et al., Chem. Biol. 3 (1), 57 (1996).

    Article  Google Scholar 

  27. M. Lindqvist and A. Graslund, J. Mol. Biol. 314 (3), 423 (2001).

    Article  Google Scholar 

  28. M. Ghomi, R. Letellier, J. Liquier, et al., Int. J. Biochem. 22 (7), 691 (1990).

    Article  Google Scholar 

  29. E. E. Tymchenko, A. A. Soldatova, E. V. Chikhirzhina, et al., J. Phys.: Conf. Ser. 1400, 066026 (2019).

    Google Scholar 

  30. H. Sfihi, J. Liquier, L. Urpi, et al., Biopolymers 33 (11), 1715 (1993).

    Article  Google Scholar 

  31. A. P. White and J. W. Powell, Biochemistry 34 (4), 1137 (1995).

    Article  Google Scholar 

  32. J. Liquiers, E. Taillandier, W. L. Peticolas, et al., J. Biomol. Struct. Dyn. 8 (2), 295 (1990).

    Article  Google Scholar 

  33. K. Kulinska, J. Sarzyńska, T. Szabo, et al., J. Biomol. Struct. Dyn. 15 (1), 119 (1997).

    Article  Google Scholar 

  34. M. Banyay, M. Sarkar, and A. Gräslund, Biophys. Chem. 104 (2), 477 (2003).

    Article  Google Scholar 

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ACKNOWLEDGMENTS

Part of the work was carried out using the equipment of the Research Park of the St. Petersburg State University (Center for Optical and Laser Material Research, Center for Diagnostics of Functional Materials for Medicine, Pharmacology and Nanoelectronics, Cryogenic Department).

Funding

This work was financially supported by the Russian Foundation for Basic Research (project no. 18-08-01500).

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Authors and Affiliations

  1. St. Petersburg State University, 199034, St. Petersburg, Russia

    E. E. Tymchenko, A. A. Soldatova & A. M. Polyanichko

  2. Institute of Cytology, Russian Academy of Sciences, 194064, St. Petersburg, Russia

    E. V. Chikhirzhina & A. M. Polyanichko

Authors
  1. E. E. Tymchenko
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  2. A. A. Soldatova
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  3. E. V. Chikhirzhina
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  4. A. M. Polyanichko
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Corresponding author

Correspondence to A. M. Polyanichko.

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The authors declare that they have no conflicts of interest. This article does not contain any studies involving animals or human participants performed by any of the authors.

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Translated by D. Novikova

Abbreviations: IR, infrared; DNA, deoxyribonucleic acid; DDP, dichlorodiammineplatinum(II).

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Tymchenko, E.E., Soldatova, A.A., Chikhirzhina, E.V. et al. Analysis of Changes in the Structure of DNA when Interacting with Platinum Coordination Compounds by IR Spectroscopy. BIOPHYSICS 67, 15–21 (2022). https://doi.org/10.1134/S0006350922010195

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  • DOI: https://doi.org/10.1134/S0006350922010195

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