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Prevalence and risk factors of stroke in a rural area of northern China: a 10-year comparative study

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Abstract

Background and aims

Stroke is currently the leading cause of death in China; however, the past decade has produced no new epidemiological studies of stroke. Therefore, the current study aimed to compare the prevalence and risk factors of stroke between 2010 and 2019.

Methods

A comparative study was used to analyze the prevalence of risk factors for stroke in a population aged 65 years or older between 2010 and 2019. Demographic characteristics, risk factors, medical history, and other clinical characteristics were collected for all participants via door-to-door interviews and inpatient hospital records.

Results

The standardized prevalence of stroke was 7.9% in 2010 and 14.2% in 2019 (p < 0.001). The prevalence of stroke was significantly higher in men than in women (p < 0.05) for all age groups. The risk factors of stroke were being male, hypertension, and diabetes mellitus in both 2010 and 2019. When comparing the risk factors between 2010 and 2019, these risk factors were statistically significantly more strongly associated with stroke in 2019 than in 2010.

Conclusion

The current study suggests that the prevalence of stroke increased nearly by twofold in a population aged 65 years or older within the past 10 years. Hypertension, diabetes mellitus, and being male were the primary risk factors. In addition, these factors were more significantly associated with stroke in 2019 compared to 2010.

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Funding

This work was supported by the National Natural Science Foundation [grant number 82172282], Science and Technology Project of Tian** Municipal Health and Health [grant number ZC20121].

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Authors and Affiliations

  1. Department of Neurology, Bei**g Tiantan Hospital, Capital Medical University, Bei**g, China

    Ling-Yun Ma, **ghuan Gan, Wenzheng Hu, Zhichao Chen, Jiuyan Han & Yong Ji

  2. Tian** Medical University, Tian**, China

    Shuai Liu, **aoshan Du & Han Zhu

  3. Department of Neurology, Tian** Huanhu Hospital, 6 Jizhao Road, **nan District, Tian**, 300350, China

    **ao-Dan Wang, Shuai Liu, Zhihong Shi & Yong Ji

  4. China National Clinical Research Center for Neurological Diseases, 119 Nansihuan West Road, Fengtai District, Bei**g, 100070, China

    Yong Ji

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Contributions

YJ conceived this review and critically edited the manuscript for important content. X-DW and Z-HS revise the manuscript. L-YM drafted the article, with further contributions from W-ZH, Z-CC, J-YH, HZ and X-SD. SL and J-HG managed and analysed the data. All authors interpreted data and approved the final version of the article.

Corresponding author

Correspondence to Yong Ji.

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The authors declare that there are no financial or other conflicts of interest.

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The study was approved by the Committee for Medical Research Ethics at Tian** Huanhu Hospital and Tian** Health Bureau.

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Ma, LY., Wang, XD., Liu, S. et al. Prevalence and risk factors of stroke in a rural area of northern China: a 10-year comparative study. Aging Clin Exp Res 34, 1055–1063 (2022). https://doi.org/10.1007/s40520-021-02028-1

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