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Contrive Himalayan Soft Gold Cordyceps Species: a Lineage of Eumycota Bestowing Tremendous Pharmacological and Therapeutic Potential

  • Natural Products: From Chemistry to Pharmacology (C Ho, Section Editor)
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Abstract

Purpose of Review

In the present review, two strain improvement strategies viz. transformation system development and inter-specific protoplast fusion for this mushroom are hypothesized.

Recent Findings

The entomopathogenic medicinal mushroom Cordyceps species has been bestowing health biologically and pharmacologically for years. It harbors a variety of bio-metabolites having far-ranging activities. One of the constituents, cordycepin alone, is involved in a plethora of biochemical and molecular processes. With this interest, the bottlenecks such as excessive harvesting, commercial cultivation, low frequency of artificial stromata formation are still on pace. The genus Cordyceps has characteristic genomic expansion and studies such as identification of mating-type genes, metabolite-producing genes, and strain improvement techniques are in great demand.

Summary

In order to understand the present demand and current scenario regarding the genus Cordyceps, efforts have been made to elucidate the significance of its major bioactive constituent and underlying wide-spectrum applications. Furthermore, through this review, one may understand the situation and demand of mushroom in the present world. Furthermore, this article would certainly help to maneuver this fungus for develo** drugs against dreadful human diseases.

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Acknowledgments

The authors are obliged to Vice Chancellor, R.D. University Jabalpur and eternal gratefulness to Head, Department of Biological Science, R.D. University, Jabalpur, for completing this review. Authors are also thankful for the project Bio-Design Innovation Centre, Grant No.-F.No.17-14/2014P.N. I, M.H.R.D., New Delhi, India, for providing study platform.

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Authors and Affiliations

  1. Fungal Biotechnology and Invertebrate Pathology Laboratory, Department of Biological Science, RD University, Jabalpur, Madhya Pradesh, 482001, India

    Loknath Deshmukh & Sardul Singh Sandhu

  2. Department of Biotechnology, Maharshi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, 133207, India

    Anil K. Sharma

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  1. Loknath Deshmukh
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Correspondence to Anil K. Sharma or Sardul Singh Sandhu.

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Deshmukh, L., Sharma, A.K. & Sandhu, S.S. Contrive Himalayan Soft Gold Cordyceps Species: a Lineage of Eumycota Bestowing Tremendous Pharmacological and Therapeutic Potential. Curr Pharmacol Rep 6, 155–166 (2020). https://doi.org/10.1007/s40495-020-00223-8

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