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Skin Metastasis of Laryngeal Carcinoma Presenting as Multiple Eruptive Nodules

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Abstract

Metastasis of head and neck squamous cell carcinoma (SCC) to the skin of this region is extremely rare and reported in 1–2% of cases. The cutaneous metastases of head and neck cancers often present as multiple papulonodular lesions; however, sporadic cases of solitary or multiple keratoacanthoma-like lesions are reported. We describe a rare case of cutaneous metastases of laryngeal SCC presenting as multiple eruptive keratoacanthoma-like lesions with concomitant scrofuloderma in an area of previous radiotherapy.

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References

  1. Ellis DL, Riahi RR, Murina AT, Cohen PR. Metastatic laryngeal carcinoma mimicking eruptive keratoacanthomas: report of keratoacanthoma-like cutaneous metastases in a radiation port. Dermatol Online J. 2014;20(9).

  2. Krathen RA, Orengo IF, Rosen T. Cutaneous metastasis: a meta-analysis of data. South Med J. 2003;96(2):164–7.

    Article  Google Scholar 

  3. Riahi RR, Cohen PR. Malignancies with skin lesions mimicking keratoacanthoma. Dermatol Online J. 2013;19(11):20397.

    PubMed  Google Scholar 

  4. Kovacs K, Kenessey I, Tímár J. Skin metastasis of internal cancers: a single institution experience. Pathol Oncol Res. 2013;19(3):515–20.

    Article  CAS  Google Scholar 

  5. Handa U, Kundu R, Dimri K. Cutaneous metastasis: a study of 138 cases diagnosed by fine-needle aspiration cytology. Acta Cytol. 2017;61(1):47–544.

    Article  Google Scholar 

  6. Pitman KT, Johnson JT. Skin metastases from head and neck squamous cell carcinoma: incidence and impact. J Sci Spec Head Neck. 1999;21(6):560–5.

    Article  CAS  Google Scholar 

  7. Alcaraz I, Cerroni L, Ruetten A, Kutzner H, Requena L. Cutaneous metastases from internal malignancies: a clinicopathologic and immunohistochemical review. Am J Dermatopathol. 2012;34(4):347–93.

    Article  Google Scholar 

  8. Veraldi S, Cantu A II, Sala F, Schianchi R, Gasparini G. Cutaneous metastases from laryngeal carcinoma. J Dermatol Surg Oncol. 1988;14(5):562–4.

    Article  CAS  Google Scholar 

  9. Trehan R, Pandey AK, Khosla D, Dimri K, Punia RS. Apropos of a case of cutaneous metastasis from laryngeal cancer with review of literature. J Cancer Res Ther. 2015;11(3):655.

    PubMed  Google Scholar 

  10. Bottoni U, Innocenzi D, Mannooranparampil TJ, Richetta A, Del Giudice M, Calvieri S. Inflammatory cutaneous metastasis from laryngeal carcinoma. Eur J Dermatol. 2001;11(2):124–6.

    CAS  PubMed  Google Scholar 

  11. Brownstein MH, Helwig EB. Metastatic tumors of the skin. Cancer. 1972;29(5):1298–307.

    Article  CAS  Google Scholar 

  12. Ruocco V, Brunetti G, Puca RV, Ruocco E. The immunocompromised district: a unifying concept for lymphoedematous, herpes-infected and otherwise damaged sites. J Eur Acad Dermatol Venereol. 2009;23(12):1364–73.

    Article  CAS  Google Scholar 

  13. Ruocco E, Di Maio R, Caccavale S, Siano M, Lo SA. Radiation dermatitis, burns, and recall phenomena: meaningful instances of immunocompromised district. Clin Dermatol. 2014;32(5):660–9.

    Article  Google Scholar 

  14. Ruocco V, Ruocco E, Brunetti G, Sangiuliano S, Wolf R. Opportunistic localization of skin lesions on vulnerable areas. Clin Dermatol. 2011;29(5):483–8.

    Article  Google Scholar 

  15. Trosman SJ, Koyfman SA, Ward MC, et al. Effect of human papillomavirus on patterns of distant metastatic failure in oropharyngeal squamous cell carcinoma treated with chemoradiotherapy. JAMA Otolaryngol Head Neck Surg. 2015;141(5):457–62.

    Article  Google Scholar 

  16. Niharika D, Sunder S, Narayanan GS, Nandennavar M. Unusual metastatic presentation of carcinoma hypopharynx. J Cancer Res Ther. 2015;11(3):666.

    Article  CAS  Google Scholar 

  17. Shindo M, Yoshida Y, Tominaga K, Yamamoto O. Skin metastasis of hypopharyngeal carcinoma to the nasal tip. Yonago Acta Med. 2013;56(2):57.

    PubMed  PubMed Central  Google Scholar 

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Correspondence to Sahar Dadkhahfar.

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Araghi, F., Fatemi, A., Rakhshan, A. et al. Skin Metastasis of Laryngeal Carcinoma Presenting as Multiple Eruptive Nodules. Head and Neck Pathol 14, 1154–1157 (2020). https://doi.org/10.1007/s12105-020-01143-1

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  • DOI: https://doi.org/10.1007/s12105-020-01143-1

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