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Hemorrhagic Complications Associated with Ventriculostomy in Patients Undergoing Endovascular Treatment for Intracranial Aneurysms: A Single-Center Experience

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Abstract

Background

Currently, a complete understanding of post-ventriculostomy hemorrhagic complications in subarachnoid hemorrhage due to ruptured aneurysms remains unknown. The present study evaluates the impact of periprocedural risk factors on rates of external ventricular drain (EVD)-associated hemorrhage in the setting of endovascular treatment of intracranial aneurysms.

Methods

A retrospective chart review of 107 patients who underwent EVD placement within 24 h of endovascular coiling was performed. CT of head without contrast was obtained after drain placement and before endovascular treatment. Post-procedural CT was also obtained within 48 h of embolization and was reviewed for new/worsened track hemorrhages. Chi-squared test was used in evaluation.

Results

Ninety-three of the 107 patients reviewed met the inclusion criteria. Four (25%) of the 16 patients on antiplatelet medications at presentation experienced post-EVD hemorrhage compared to 11 (14.3%) of 77 that were not (p = 0.29). Of the 13 patients given intraprocedural antiplatelets, 3 (23.1%) demonstrated hemorrhage compared to 12 (15%) of 80 not administered these medications (p = 0.46). Further, of 36 patients with intraprocedural anticoagulation, 6 (16.7%) exhibited hemorrhage compared to 9 (15.8%) of 57 in those without (p = 0.91). In 17 patients who received DVT prophylaxis, 2 (11.8%) exhibited hemorrhage compared to 13 (17.1%) of 76 who did not (p = 0.59). No post-EVD hemorrhage had attributable neurologic morbidity.

Conclusion

Our results, demonstrating no significant risk factor related to EVD-associated hemorrhage rates, support the safety of EVD placement in the peri-endovascular treatment period.

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Authors and Affiliations

  1. Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA

    Jack M. Leschke, Mazen Noufal & Osama Zaidat

  2. Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA

    Andrew Lozen, Akinwunmi Oni-Orisan, Glen A. Pollock & Wade M. Mueller

  3. Department of Biomedical Engineering, Marquette University, 1250 W Wisconsin Ave, Milwaukee, WI, 53233, USA

    Mayank Kaushal

Authors
  1. Jack M. Leschke
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Correspondence to Mayank Kaushal.

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Leschke, J.M., Lozen, A., Kaushal, M. et al. Hemorrhagic Complications Associated with Ventriculostomy in Patients Undergoing Endovascular Treatment for Intracranial Aneurysms: A Single-Center Experience. Neurocrit Care 27, 11–16 (2017). https://doi.org/10.1007/s12028-016-0350-y

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  • DOI: https://doi.org/10.1007/s12028-016-0350-y

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