Log in

Recent advances in pharmaceuticals and personal care products in the surface water and sediments in China

  • Review Article
  • Published:
Frontiers of Environmental Science & Engineering Aims and scope Submit manuscript

Abstract

Pharmaceuticals and personal care products (PPCPs) have been regarded as an emerging problem in the surface water environment in the past few decades. In China, although related studies were initiated several years ago, an increasing number of studies on this topic have been conducted in recent years. These studies have expanded knowledge of their occurrence, behavior and associated risk in the surface water environment in China. This review compiles the most recent literature related to the studies of PPCPs in the surface water environment in China. It includes PPCP occurrence in surface water and sediments, their geographical distribution, and outcomes of the associated risk assessment. It shows that antibiotics have received much more attention in both surface water and sediments than other PPCPs. Compared to other countries; most antibiotics in the collected sediments in China showed higher contamination levels. Many more study areas have been covered in recent years; however, attention has been given to only specific areas. Environmental risk assessment based on risk quotients indicated that sulfamethoxazole presents the most significant environmental risk to relevant aquatic organisms; followed by ofloxacin, ciprofloxacin, enrofloxacin, 17α-ethynylestradiol, ibuprofen and diclofenac. Despite limited research on the environmental risk assessment of PPCPs in sediments, higher risks posed by PPCPs in the sediments rather than surface water were identified highlighting the need for further risk assessment of PPCPs in sediment samples.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Germany)

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Daughton C G, Ternes T A. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environmental Health Perspectives, 1999, 107(Suppl 6): 907–938

    Article  CAS  Google Scholar 

  2. Corbel V, Stankiewicz M, Pennetier C, Fournier D, Stojan J, Girard E, Dimitrov M, Molgó J, Hougard J M, Lapied B. Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet. BMC Biology, 2009, 7(1): 47

    Article  Google Scholar 

  3. Ricart M, Guasch H, Alberch M, Barceló D, Bonnineau C, Geiszinger A, Farré M, Ferrer J, Ricciardi F, Romaní A M, Morin S, Proia L, Sala L, Sureda D, Sabater S. Triclosan persistence through wastewater treatment plants and its potential toxic effects on river biofilms. Aquatic Toxicology (Amsterdam, Netherlands), 2010, 100(4): 346–353

    Article  CAS  Google Scholar 

  4. European Commission. Directive 2000/60/EC of the European Parliament and of the Council establishing a framework for the Community action in the field of water policy, 23 October 2000. Official Journal of the European Communities, 2000, 12: L327

    Google Scholar 

  5. Barbosa M O, Moreira N F F, Ribeiro A R, Pereira M F R, Silva A M T. Occurrence and removal of organic micropollutants: An overview of the watch list of EU Decision 2015/495. Water Research, 2016, 94: 257–279

    Article  CAS  Google Scholar 

  6. Schwab B W, Hayes E P, Fiori J M, Mastrocco F J, Roden N M, Cragin D, Meyerhoff R D, D’Aco V J, Anderson P D. Human pharmaceuticals in US surface waters: a human health risk assessment. Regulatory Toxicology and Pharmacology, 2005, 42(3): 296–312

    Article  CAS  Google Scholar 

  7. Kümmerer K. Antibiotics in the aquatic environment: a review—Part I. Chemosphere, 2009, 75(4): 417–434

    Article  Google Scholar 

  8. Mompelat S, Le Bot B, Thomas O. Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water. Environment International, 2009, 35(5): 803–814

    Article  CAS  Google Scholar 

  9. Liu J L, Wong M H. Pharmaceuticals and personal care products (PPCPs): a review on environmental contamination in China. Environment International, 2013, 59(3): 208–224

    Article  CAS  Google Scholar 

  10. Bu Q, Wang B, Huang J, Deng S, Yu G. Pharmaceuticals and personal care products in the aquatic environment in China: a review. Journal of Hazardous Materials, 2013, 262(22): 189–211

    Article  CAS  Google Scholar 

  11. Yang G, Fan M, Zhang G. Emerging contaminants in surface waters in China: a short review. Environmental Research Letters, 2014, 9(7): 1–13

    Article  Google Scholar 

  12. Yin L N, Wang B, Ma R X, Yuan H L, Yu G. Enantioselective environmental behavior and effect of chiral PPCPs. Progress in Chemistry., 2016, 28(5): 744–753

    Google Scholar 

  13. Chen M, Yi Q T, Hong J J, Zhang L M, Lin K D, Yuan D X. Simultaneous determination of 32 antibiotics and 12 pesticides in sediment using ultrasonic-assisted extraction and high performance liquid chromatography-tandem mass spectrometry. Analytical Methods, 2015, 7(5): 1896–1905

    Article  CAS  Google Scholar 

  14. Chen Z F, Ying G G, Lai H J, Chen F, Su H C, Liu Y S, Peng F Q, Zhao J L. Determination of biocides in different environmental matrices by use of ultra-high-performance liquid chromatographytandem mass spectrometry. Analytical and Bioanalytical Chemistry, 2012, 404(10): 3175–3188

    Article  CAS  Google Scholar 

  15. Hu X, He K, Zhou Q. Occurrence, accumulation, attenuation and priority of typical antibiotics in sediments based on long-term field and modeling studies. Journal of Hazardous Materials, 2012, 225–226: 91–98

    Article  Google Scholar 

  16. Huang Q, Wang Z, Wang C, Peng X. Chiral profiling of azole antifungals in municipal wastewater and recipient rivers of the Pearl River Delta, China. Environmental Science and Pollution Research International, 2013, 20(12): 8890–8899

    Article  CAS  Google Scholar 

  17. Huang S, Zhu F, Jiang R, Zhou S, Zhu D, Liu H, Ouyang G. Determination of eight pharmaceuticals in an aqueous sample using automated derivatization solid-phase microextraction combined with gas chromatography-mass spectrometry. Talanta, 2015, 136: 198–203

    Article  CAS  Google Scholar 

  18. Liang X, Chen B, Nie X, Shi Z, Huang X, Li X. The distribution and partitioning of common antibiotics in water and sediment of the Pearl River Estuary, South China. Chemosphere, 2013, 92(11): 1410–1416

    Article  CAS  Google Scholar 

  19. Shi H, Yang Y, Liu M, Yan C, Yue H, Zhou J. Occurrence and distribution of antibiotics in the surface sediments of the Yangtze Estuary and nearby coastal areas. Marine Pollution Bulletin, 2014, 83(1): 317–323

    Article  CAS  Google Scholar 

  20. Shi X, Zhou J L, Zhao H, Hou L, Yang Y. Application of passive sampling in assessing the occurrence and risk of antibiotics and endocrine disrupting chemicals in the Yangtze Estuary, China. Chemosphere, 2014, 111: 344–351

    Article  CAS  Google Scholar 

  21. Song H, Zeng X, Yu Z, Zhang D, Cao S, Shao W, Sheng G, Fu J. Enantiomeric composition of polycyclic musks in sediments from the Pearl River and Suzhou Creek. Environmental Science and Pollution Research International, 2015, 22(3): 1679–1686

    Article  CAS  Google Scholar 

  22. Xu W, Yan W, Li X, Zou Y, Chen X, Huang W, Miao L, Zhang R, Zhang G, Zou S. Antibiotics in riverine runoff of the Pearl River Delta and Pearl River Estuary, China: concentrations, mass loading and ecological risks. Environmental Pollution, 2013, 182(6): 402–407

    Article  CAS  Google Scholar 

  23. Zhang X, Zhang D, Zhang H, Luo Z, Yan C. Occurrence, distribution, and seasonal variation of estrogenic compounds and antibiotic residues in Jiulongjiang River, South China. Environmental Science and Pollution Research International, 2012, 19(5): 1392–1404

    Article  CAS  Google Scholar 

  24. Yang X, Chen F, Meng F, **e Y, Chen H, Young K, Luo W, Ye T, Fu W. Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China. Environmental Science and Pollution Research International, 2013, 20(8): 5864–5875

    Article  CAS  Google Scholar 

  25. Ma R, Wang B, Lu S, Zhang Y, Yin L, Huang J, Deng S, Wang Y, Yu G. Characterization of pharmaceutically active compounds in Dongting Lake, China: occurrence, chiral profiling and environmental risk. Science of the Total Environment, 2016, 557–558: 268–275

    Article  Google Scholar 

  26. Wang B, Dai G, Deng S, Huang J, Wang Y, Yu G. Linking the environmental loads to the fate of PPCPs in Bei**g: considering both the treated and untreated wastewater sources. Environmental Pollution, 2015, 202: 153–159

    Article  CAS  Google Scholar 

  27. Dai G, Wang B, Fu C, Dong R, Huang J, Deng S, Wang Y, Yu G. Pharmaceuticals and personal care products (PPCPs) in urban and suburban rivers of Bei**g, China: occurrence, source apportionment and potential ecological risk. Environmental Science. Processes & Impacts, 2016, 18(4): 445–455

    Article  CAS  Google Scholar 

  28. Ma R, Wang B, Yin L, Zhang Y, Deng S, Huang J, Wang Y, Yu G. Characterization of pharmaceutically active compounds in Bei**g, China: occurrence pattern, spatiotemporal distribution and its environmental implication. Journal of Hazardous Materials, 2016, 10.1016/j.jhazmat.2016.05.030

    Google Scholar 

  29. Wang D, Sui Q, Zhao W T, Lu S G, Qiu Z F, Yu G. Pharmaceutical and personal care products in the surface water of China: a review. China Environmental Science, 2014, 59(59): 743–751(in Chinese)

    Google Scholar 

  30. Luo Y, Mao D, Rysz M, Zhou Q, Zhang H, Xu L, J J Alvarez P. Trends in antibiotic resistance genes occurrence in the Haihe River, China. Environmental Science & Technology, 2010, 44(19): 7220–7225

    Article  Google Scholar 

  31. Lu Z H, Na G S, Gao H, Wang L J, Bao C G, Yao Z W. Fate of sulfonamide resistance genes in estuary environment and effect of anthropogenic activities. Science of the Total Environment, 2015, 527–528: 429–438

    Article  Google Scholar 

  32. Lin L, Yuan K, Liang X, Chen X, Zhao Z, Yang Y, Zou S, Luan T, Chen B. Occurrences and distribution of sulfonamide and tetracycline resistance genes in the Yangtze River Estuary and nearby coastal area. Marine Pollution Bulletin, 2015, 100(1): 304–310

    Article  CAS  Google Scholar 

  33. Li W, Shi Y, Gao L, Liu J, Cai Y. Occurrence of antibiotics in water, sediments, aquatic plants, and animals from Baiyangdian Lake in North China. Chemosphere, 2012, 89(11): 1307–1315

    Article  CAS  Google Scholar 

  34. Duan Y P, Dai C M, Zhang Y L, Chen L. Selective trace enrichment of acidic pharmaceuticals in real water and sediment samples based on solid-phase extraction using multi-templates molecularly imprinted polymers. AnalyticaChimicaActa, 2013, 758: 93–100

    CAS  Google Scholar 

  35. Lu G, Yang X, Li Z, Zhao H, Wang C. Contamination by metals and pharmaceuticals in northern Taihu Lake (China) and its relation to integrated biomarker response in fish. Ecotoxicology (London, England), 2013, 22(1): 50–59

    Article  CAS  Google Scholar 

  36. Zhu S, Chen H, Li J. Sources, distribution and potential risks of pharmaceuticals and personal care products in Qingshan Lake basin, Eastern China. Ecotoxicology and Environmental Safety, 2013, 96(6): 154–159

    Article  CAS  Google Scholar 

  37. Wei Y M, Zhang Y, Xu J, Guo C S, Li L, Fan W H. Simultaneous quantification of several classes of antibiotics in water, sediments, and fish muscles by liquid chromatography–tandem mass spectrometry. Frontiers of Environmental Science and Engineering, 2014, 8(3): 357–371

    Article  CAS  Google Scholar 

  38. Xu J, Zhang Y, Zhou C B, Guo C S, Wang D M, Du P, Luo Y, Wan J, Meng W. Distribution, sources and composition of antibiotics in sediment, overlying water and pore water from Taihu Lake, China. Science of the Total Environment, 2014, 497–498: 267–273

    Article  Google Scholar 

  39. Tong L, Huang S, Wang Y, Liu H, Li M. Occurrence of antibiotics in the aquatic environment of Jianghan Plain, central China. Science of the Total Environment, 2014, 497-498: 180–187

    Article  CAS  Google Scholar 

  40. Cheng D M, Liu X H, Wang L, Gong WW, Liu G N, Fu WJ, Cheng M. Seasonal variation and sediment–water exchange of antibiotics in a shallower large lake in North China. Science of the Total Environment, 2014, 476–477: 266–275

    Article  Google Scholar 

  41. Tang J, Shi T, Wu X, Cao H, Li X, Hua R, Tang F, Yue Y. The occurrence and distribution of antibiotics in Lake Chaohu, China: seasonal variation, potential source and risk assessment. Chemosphere, 2015, 122: 154–161

    Article  CAS  Google Scholar 

  42. Lei X, Lu J, Liu Z, Tong Y, Li S. Concentration and distribution of antibiotics in water-sediment system of Bosten Lake, **njiang. Environmental Science and Pollution Research International, 2015, 22(3): 1670–1678

    Article  CAS  Google Scholar 

  43. Zhang R, Zhang G, Zheng Q, Tang J, Chen Y, Xu W, Zou Y, Chen X. Occurrence and risks of antibiotics in the Laizhou Bay, China: impacts of river discharge. Ecotoxicology and Environmental Safety, 2012, 80(2): 208–215

    Article  CAS  Google Scholar 

  44. Zhang R, Tang J, Li J, Zheng Q, Liu D, Chen Y, Zou Y, Chen X, Luo C, Zhang G. Antibiotics in the offshore waters of the Bohai Sea and the Yellow Sea in China: occurrence, distribution and ecological risks. Environmental Pollution, 2013, 174(5): 71–77

    Article  CAS  Google Scholar 

  45. Zheng Q, Zhang R, Wang Y, Pan X, Tang J, Zhang G. Occurrence and distribution of antibiotics in the Beibu Gulf, China: impacts of river discharge and aquaculture activities. Marine Environmental Research, 2012, 78(8): 26–33

    Article  CAS  Google Scholar 

  46. Zhang H, Liu P, Feng Y, Yang F. Fate of antibiotics during wastewater treatment and antibiotic distribution in the effluentreceiving waters of the Yellow Sea, northern China. Marine Pollution Bulletin, 2013, 73(1): 282–290

    Article  CAS  Google Scholar 

  47. Na G, Fang X, Cai Y, Ge L, Zong H, Yuan X, Yao Z, Zhang Z. Occurrence, distribution, and bioaccumulation of antibiotics in coastal environment of Dalian, China. Marine Pollution Bulletin, 2013, 69(1–2): 233–237

    Article  CAS  Google Scholar 

  48. Lv M, Sun Q, Hu A, Hou L, Li J, Cai X, Yu C P. Pharmaceuticals and personal care products in a mesoscale subtropical watershed and their application as sewage markers. Journal of Hazardous Materials, 2014, 280: 696–705

    Article  CAS  Google Scholar 

  49. Yan Q, Gao X, Chen Y P, Peng X Y, Zhang Y X, Gan X M, Zi C F, Guo J S. Occurrence, fate and ecotoxicological assessment of pharmaceutically active compounds in wastewater and sludge from wastewater treatment plants in Chongqing, the Three Gorges Reservoir Area. Science of the Total Environment, 2014, 470–471(2): 618–630

    Article  Google Scholar 

  50. Sui Q, Huang J, Deng S, Chen W, Yu G. Seasonal variation in the occurrence and removal of pharmaceuticals and personal care products in different biological wastewater treatment processes. Environmental Science & Technology, 2011, 45(8): 3341–3348

    Article  CAS  Google Scholar 

  51. Sui Q, Wang D, Zhao W T, Huang J, Yu G, Cao X Q, Qiu Z F, Lu S G. Removal of pharmaceutical and personal care products by sequential ultraviolet and ozonation process in a full-scale wastewater treatment plant. Frontiers of Environmental Science and Engineering, 2014, 8(1): 62–68

    Article  CAS  Google Scholar 

  52. Sui Q, Wang D, Zhao W, Huang J, Yu G, Cao X, Qiu Z, Lu S. Pharmaceuticals and consumer products in four wastewater treatment plants in urban and suburb areas of Shanghai. Environmental Science and Pollution Research International, 2015, 22(8): 6086–6094

    Article  CAS  Google Scholar 

  53. Li X W, Shi H C, Li K X, Zhang L, Gan Y P. Occurrence and fate of antibiotics in advanced wastewatertreatment facilities and receiving rivers in Bei**g, China. Frontiers of Environmental Science and Engineering, 2014, 8(6): 888–894

    Article  CAS  Google Scholar 

  54. Du J, Fan Y, Qian X. Occurrence and behavior of pharmaceuticals in sewagetreatment plants in eastern China. Frontiers of Environmental Science and Engineering, 2015, 9(4): 725–730

    Article  CAS  Google Scholar 

  55. Xue B, Zhang R, Wang Y, Liu X, Li J, Zhang G. Antibiotic contamination in a typical develo** city in south China: occurrence and ecological risks in the Yongjiang River impacted by tributary discharge and anthropogenic activities. Ecotoxicology and Environmental Safety, 2013, 92(3): 229–236

    Article  CAS  Google Scholar 

  56. Chen Y, Leung K S Y, Wong J W C, Selvam A. Preliminary occurrence studies of antibiotic residues in Hong Kong and Pearl River Delta. Environmental Monitoring and Assessment, 2013, 185(1): 745–754

    Article  CAS  Google Scholar 

  57. Zhang X, Li Y, Liu B, Wang J, Feng C, Gao M, Wang L. Prevalence of veterinary antibiotics and antibiotic-resistant Escherichia coli in the surface water of a livestock production region in northern China. PLoS ONE, 2014, 9(11): e111026

    Article  Google Scholar 

  58. Chen K, Zhou J L. Occurrence and behavior of antibiotics in water and sediments from the Huangpu River, Shanghai, China. Chemosphere, 2014, 95(5): 604–612

    Article  CAS  Google Scholar 

  59. Liu J, Lu G, **e Z, Zhang Z, Li S, Yan Z. Occurrence, bioaccumulation and risk assessment of lipophilic pharmaceutically active compounds in the downstream rivers of sewage treatment plants. Science of the Total Environment, 2015, 511: 54–62

    Article  CAS  Google Scholar 

  60. Dai G, Wang B, Huang J, Dong R, Deng S, Yu G. Occurrence and source apportionment of pharmaceuticals and personal care products in the Beiyun River of Bei**g, China. Chemosphere, 2015, 119 (119C): 1033–1039

    Article  CAS  Google Scholar 

  61. Jiang L, Hu X, Yin D, Zhang H, Yu Z. Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China. Chemosphere, 2011, 82(6): 822–828

    Article  CAS  Google Scholar 

  62. Chen Z F, Ying G G, Liu Y S, Zhang Q Q, Zhao J L, Liu S S, Chen J, Peng F J, Lai H J, Pan C G. Triclosan as a surrogate for household biocides: an investigation into biocides in aquatic environments of a highly urbanized region. Water Research, 2014, 58(7): 269–279

    Article  CAS  Google Scholar 

  63. Zhao J L, Ying G G, Liu Y S, Chen F, Yang J F, Wang L. Occurrence and risks of triclosan and triclocarban in the Pearl River system, South China: from source to the receiving environment. Journal of Hazardous Materials, 2010, 179(1–3): 215–222

    Article  CAS  Google Scholar 

  64. Yang J F, Ying G G, Zhao J L, Tao R, Su H C, Chen F. Simultaneous determination of four classes of antibiotics in sediments of the Pearl Rivers using RRLC-MS/MS. Science of the Total Environment, 2010, 408(16): 3424–3432

    Article  CAS  Google Scholar 

  65. Yang Y, Fu J, Peng H, Hou L, Liu M, Zhou J L. Occurrence and phase distribution of selected pharmaceuticals in the Yangtze Estuary and its coastal zone. Journal of Hazardous Materials, 2011, 190(1–3): 588–596

    Article  CAS  Google Scholar 

  66. Luo Y, Xu L, Rysz M, Wang Y, Zhang H, Alvarez P J J. Occurrence and transport of tetracycline, sulfonamide, quinolone, and macrolide antibiotics in the Haihe River Basin, China. Environmental Science & Technology, 2011, 45(5): 1827–1833

    Article  CAS  Google Scholar 

  67. Zhao J L, Zhang Q Q, Chen F, Wang L, Ying G G, Liu Y S, Yang B, Zhou L J, Liu S, Su H C, Zhang R Q. Evaluation of triclosan and triclocarban at river basin scale using monitoring and modeling tools: implications for controlling of urban domestic sewage discharge. Water Research, 2013, 47(1): 395–405

    Article  CAS  Google Scholar 

  68. Bai Y, Meng W, Xu J, Zhang Y, Guo C. Occurrence, distribution and bioaccumulation of antibiotics in the Liao River Basin in China. Environmental Science. Processes & Impacts, 2014, 16(3): 586–593

    Article  CAS  Google Scholar 

  69. Kim S C, Carlson K. Quantification of human and veterinary antibiotics in water and sediment using SPE/LC/MS/MS. Analytical and Bioanalytical Chemistry, 2007, 387(4): 1301–1315

    Article  CAS  Google Scholar 

  70. Arikan O A, Rice C, Codling E. Occurrence of antibiotics and hormones in a major agricultural watershed. Desalination, 2008, 226 (1–3): 121–133

    Article  CAS  Google Scholar 

  71. Vazquez-Roig P, Andreu V, Blasco C, Picó Y. Risk assessment on the presence of pharmaceuticals in sediments, soils and waters of the Pego-Oliva Marshlands (Valencia, eastern Spain). Science of the Total Environment, 2012, 440(3): 24–32

    Article  CAS  Google Scholar 

  72. Matongo S, Birungi G, Moodley B, Ndungu P. Pharmaceutical residues in water and sediment of Msunduzi River, KwaZulu-Natal, South Africa. Chemosphere, 2015, 134: 133–140

    Article  CAS  Google Scholar 

  73. Zhou J, Broodbank N. Sediment-water interactions of pharmaceutical residues in the river environment.Water Research, 2014, 48(1): 61–70

  74. Zhou X F, Dai C M, Zhang Y L, Surampalli R Y, Zhang T C. A preliminary study on the occurrence and behavior of carbamazepine (CBZ) in aquatic environment of Yangtze River Delta, China. Environmental Monitoring and Assessment, 2011, 173(1–4): 45–53

    Article  CAS  Google Scholar 

  75. Wang P H, Yuan T, Hu J Y, Tan Y M. Determination of cephalosporin antibiotics in water samples by optimised solid phase extraction and high performance liquid chromatography with ultraviolet detector. International Journal of Environmental Analytical Chemistry, 2011, 91(13): 1267–1281

    Article  CAS  Google Scholar 

  76. Wolf A, Bergmann A, Wilken R D, Gao X, Bi Y, Chen H, Schüth C. Occurrence and distribution of organic trace substances in waters from the Three Gorges Reservoir, China. Environmental Science and Pollution Research International, 2013, 20(10): 7124–7139

    Article  CAS  Google Scholar 

  77. Wu C, Huang X, Witter J D, Spongberg A L, Wang K, Wang D, Liu J. Occurrence of pharmaceuticals and personal care products and associated environmental risks in the central and lower Yangtze river, China. Ecotoxicology and Environmental Safety, 2014, 106: 19–26

    Article  CAS  Google Scholar 

  78. Yan C, Yang Y, Zhou J, Liu M, Nie M, Shi H, Gu L. Antibiotics in the surface water of the Yangtze Estuary: occurrence, distribution and risk assessment. Environmental Pollution, 2013, 175(8): 22–29

    Article  CAS  Google Scholar 

  79. Bu Q, Wang B, Huang J, Liu K, Deng S, Wang Y, Yu G. Estimating the use of antibiotics for humans across China. Chemosphere, 2016, 144: 1384–1390

    Article  CAS  Google Scholar 

  80. Hernando M D, Mezcua M, Fernández-Alba A R, Barceló D. Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta, 2006, 69(2): 334–342

    Article  CAS  Google Scholar 

  81. Zhang R, Tang J, Li J, Cheng Z, Chaemfa C, Liu D, Zheng Q, Song M, Luo C, Zhang G. Occurrence and risks of antibiotics in the coastal aquatic environment of the Yellow Sea, North China. Science of the Total Environment, 2013, 450–451(2): 197–204

    Article  Google Scholar 

  82. Jiang Y, Li M, Guo C, An D, Xu J, Zhang Y, ** B. Distribution and ecological risk of antibiotics in a typical effluent-receiving river (Wangyang River) in north China. Chemosphere, 2014, 112: 267–274

    Article  CAS  Google Scholar 

  83. Li N, Zhang X, Wu W, Zhao X. Occurrence, seasonal variation and risk assessment of antibiotics in the reservoirs in North China. Chemosphere, 2014, 111: 327–335

    Article  CAS  Google Scholar 

  84. Gunnarsson L, Jauhiainen A, Kristiansson E, Nerman O, Larsson D G. Evolutionary conservation of human drug targets in organisms used for environmental risk assessments. Environmental Science & Technology, 2008, 42(15): 5807–5813

    Article  CAS  Google Scholar 

  85. Wang B, Huang J, Deng S B, Yang X L, Yu G. Addressing the environmental risk of persistent organic pollutants in China. Frontiers of Environmental Science and Engineering, 2012, 6(1): 2–16

    Article  Google Scholar 

  86. Backhaus T, Faust M. Predictive environmental risk assessment of chemical mixtures: a conceptual framework. Environmental Science & Technology, 2012, 46(5): 2564–2573

    Article  CAS  Google Scholar 

  87. Wen Z H, Chen L, Meng X Z, Duan Y P, Zhang Z S, Zeng E Y. Occurrence and human health risk of wastewater-derived pharmaceuticals in a drinking water source for Shanghai, East China. Science of the Total Environment, 2014, 490: 987–993

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Wentao Zhao or Qian Sui.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhao, W., Guo, Y., Lu, S. et al. Recent advances in pharmaceuticals and personal care products in the surface water and sediments in China. Front. Environ. Sci. Eng. 10, 2 (2016). https://doi.org/10.1007/s11783-016-0868-4

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11783-016-0868-4

Keywords

Navigation