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Magnetic nanoparticles based cancer therapy: current status and applications

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Abstract

Nanotechnology holds a promising potential for develo** biomedical nanoplatforms in cancer therapy. The magnetic nanoparticles, which integrate uniquely appealing features of magnetic manipulation, nanoscale heat generator, localized magnetic field and enzyme-mimics, prompt the development and application of magnetic nanoparticles-based cancer medicine. Considerable success has been achieved in improving the magnetic resonance imaging (MRI) sensitivity, and the therapeutic function of the magnetic nanoparticles should be given adequate attention. This work reviews the current status and applications of magnetic nanoparticles based cancer therapy. The advantages of magnetic nanoparticles that may contribute to improved therapeutics efficacy of clinic cancer treatment are highlighted here.

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Acknowledgements

The authors acknowledge financial support provided by the National Natural Science Foundation of China (81571809, 81771981, 31400663, and 21376192) and the Natural Science Foundation of Shaanxi Province (2015JM2063 and 2017JM2031).

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Authors and Affiliations

  1. Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, **’an, 710069, China

    Huan Zhang, Yi Fan Zhang, Fei Gao, Ga Long Li, Yuan He, Ming Li Peng & Hai Ming Fan

  2. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Bei**g, 100190, China

    **ao Li Liu

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  1. Huan Zhang
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Correspondence to Hai Ming Fan.

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Zhang, H., Liu, X.L., Zhang, Y.F. et al. Magnetic nanoparticles based cancer therapy: current status and applications. Sci. China Life Sci. 61, 400–414 (2018). https://doi.org/10.1007/s11427-017-9271-1

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