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Copper (II) complexes with (E)-N′(3,5-di-tert-butyl-2-hydroxybenzilidene)-2-hydroxybenzohydrazide, their bactericidal and fungicidal activity

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Abstract

Mononuclear complexes of Copper(II) with (E)-N′(3,5-di-tert-butyl-2-hydroxybenzili- dene)-2-hydroxybenzohydrazide (H3sahz)2, Cu(Hsahz)(H2O) and Cu(Hsahz)(DMF) were synthesized. The structure of the complexes was studied by elemental analysis, IR and EPR spectroscopy, and single-crystal X-ray analysis. It was shown that the complexes have a square-planar structure, in which the ligand is tridentate and dianionic. The coordination of Cu(II) ion is formed by the oxygen atom of the phenol group of 3,5-di-tert-butyl salicylic aldehyde, amidic oxygen atom is in enolic form, the oxygen atom of the DMF molecule and the nitrogen atom of the azomethine group. When recrystallizing from DMF/acetonitrile/ethanol = 1:2:4 solution, the water molecule in the complex is easily exchanged with the DMF molecule. The results of these studies showed that the complexes have a stronger antibacterial and antifungal effect than the ligand.

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Authors and Affiliations

  1. Institute of Catalysis and Inorganic Chemistry, Ministry of Science and Education of the Republic of Azerbaijan, Baku, Azerbaijan

    Perizad Amrulla Fatullayeva, Ajdar Akper Medjidov, Rayyat Huseyn Ismayilov, Gulu Qanimet Abbasova & Esmira Arif Aga Quliyeva

  2. Institute of Radiation Problems, Ministry of Science and Education of the Republic of Azerbaijan, Baku, Azerbaijan

    Asim Sabri Abdullayev & Mahammad Allahverdi Bayramov

  3. Gazakh Branch of Baku State University, Baku, Azerbaijan

    Sevinc Rafiq Lahicova

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  1. Perizad Amrulla Fatullayeva
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Contributions

F.P. synthesized the ingredients. She participated in the discussion of the article. M.A. participated in the organization and discussion of the article. R.I. participated in the organization and discussion of the article. A.A. participated in the study of the physicochemical properties of the synthesized substances. S.L. He had a role in the study of the biological activity of substances. A.G. Participated in drawing infrared spectra. G.E. He played a role in drawing electronic spectra. M.B. played a role in drawing EPR spectra.

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Correspondence to Perizad Amrulla Fatullayeva.

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Fatullayeva, P.A., Medjidov, A.A., Ismayilov, R.H. et al. Copper (II) complexes with (E)-N′(3,5-di-tert-butyl-2-hydroxybenzilidene)-2-hydroxybenzohydrazide, their bactericidal and fungicidal activity. Transit Met Chem 49, 129–136 (2024). https://doi.org/10.1007/s11243-023-00568-1

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