Abstract
Nanotechnology is a rapidly growing field of science and technology, which deals with development of new solutions by understanding and controlling matter at nanoscale level. Silver nanoparticles (AgNPs) are one of the most recognized nanomaterials that are incorporated in a wide range of extensive applications due to their unique properties. Over the past years, scientific interest in using AgNPs in the field of plant biotechnology and agriculture has gained momentum. Acknowledging this aspect of application of AgNPs, the present review delved into the numerous research studies conducted to explore the effects of AgNPs on in-vitro seed germination, plant propagation and metabolite production highlighting their positive as well as the negative aspects. The suggested mechanism of action of AgNPs on plants and limitations faced in applying these nanoparticles on a commercial scale are also discussed. While AgNPs have demonstrated massive potential in plant tissue culture, their application in enhancing overall plant growth have demonstrated conflicting outcomes in different plant species. This clearly highlights that there is a need for more in-depth research in order to understand the intricate complexities involved in nanoparticle action and their inherent phytotoxic nature.
Key message
The current review article provides a detailed outlook about the studies that have investigated the in-vitro applications of silver nanoparticles in facilitating seed germination, promotion of plant growth and metabolite production. The probable mechanism of action of AgNPs has also been discussed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abdi G, Salehi H, Khosh-Khui M (2008) Nano silver: a novel nanomaterial for removal of bacterial contaminants in valerian (Valeriana officinalis L.) tissue culture. Acta Physiol Plant 30:709–714. https://doi.org/10.1007/s11738-008-0169-z
Abou El-Nour KMM, Eftaiha A, Al-Warthan A, Ammar RAA (2010) Synthesis and applications of silver nanoparticles. Arab J Chem 3:135–140. https://doi.org/10.1016/j.arabjc.2010.04.008
Aghdaei M, Salehi H, Sarmast MK (2012) Effects of silver nanoparticles on Tecomella undulata (Roxb.) Seem. micropropagation. Adv Hort Sci 26:21–24
Al-Huqail AA, Hatata MM, AL-Huqail AA, Ibrahim MM (2018) Preparation, characterization of silver phyto nanoparticles and their impact on growth potential of Lupinus termis L. seedlings. Saudi J Biol Sci 25(2):313–319. https://doi.org/10.1016/j.sjbs.2017.08.013
Ali A, Mohammad S, Khan MA, Raja NI, Arif M, Kamil A, Mashwani ZUR (2019) Silver nanoparticles elicited in vitro callus cultures for accumulation of biomass and secondary metabolites in Caralluma tuberculata. Artif Cells Nanomed Biotechnol 47:715–724. https://doi.org/10.1080/21691401.2019.1577884
Almutairi ZM, Alharbi A (2015) Effect of silver nanoparticles on seed germination of crop plants. J Adv Agric 4:283–288. https://doi.org/10.24297/jaa.v4i1.4295
Alshehddi LAA, Bokhari N (2020) Influence of gold and silver nanoparticles on the germination and growth of Mimusops laurifolia seeds in the South-Western regions in Saudi Arabia. Saudi J Biol Sci 27(1):574–580. https://doi.org/10.1016/j.sjbs.2019.11.013
Amooaghaie R, Tabatabaei F, Ahadi AM (2015) Role of hematin and sodium nitroprusside in regulating Brassica nigra seed germination under nanosilver and silver nitrate stresses. Ecotoxicol Environ Saf 113:259–270. https://doi.org/10.1016/j.ecoenv.2014.12.017
Arab MM, Yadollahi A, Hosseini-Mazinani M, Bagheri S (2014) Effects of antimicrobial activity of silver nanoparticles on in vitro establishment of G×N15 (hybrid of almond×peach) rootstock. J Genet Eng Biotechnol 12(2):103–110. https://doi.org/10.1016/j.jgeb.2014.10.002
Awwad A, Salem N (2012) Green synthesis of silver nanoparticles by mulberry leaves extract. Nanosci Nanotechnol 2:125–128. https://doi.org/10.5923/j.nn.20120204.06
Barbasz A, Kreczmer B, Oc ́wieja M (2016) Effects of exposure of callus cells of two wheat varieties to silver nanoparticles and silver salt (AgNO3). Acta Physiol Plant 38:76. https://doi.org/10.1007/s11738-016-2092-z
Bayramzadeh V, Ghadiri M, Davoodi M (2019) Effects of silver nanoparticle exposure on germination and early growth of Pinus sylvestris and Alnus subcordata. Sains Malaysiana 48:937–944. https://doi.org/10.17576/jsm-2019-4805-02
Begum S, Zahid A, Khan T, ZamanAli NZW (2020) Comparative analysis of the effects of chemically and biologically synthesized silver nanoparticles on biomass accumulation and secondary metabolism in callus cultures of Fagonia indica. Physiol Mol Biol Plants 26:1739–1750. https://doi.org/10.1007/s12298-020-00851-w
Bhat P, Bhat A (2016) Silver nanoparticles for enhancement of accumulation of capsaicin in suspension culture of Capsicum sp. J Exp Sci 7:1–6. https://doi.org/10.19071/jes.2016.v7.3001
Biba R, Matić D, Lyons DM, Štefanić PP, Cvjetko P, Tkalec M, Pavoković D, Letofsky-Papst I, Balen B (2020) Coating-dependent effects of silver nanoparticles on tobacco seed germination and early growth. Int J Mol Sci 21:3441. https://doi.org/10.3390/ijms21103441
Bijali J, Acharya K (2020) Current trends in nano-technological interventions on plant growth and development: a review. IET Nanobiotechnol 14:113–119. https://doi.org/10.1049/iet-nbt.2019.0008
Castro-González CG, Sánchez-Segura L, Gómez-Merino FC, Bello-Bello JJ (2019) Exposure of stevia (Stevia rebaudiana B) to silver nanoparticles in vitro: transport and accumulation. Sci Rep 9:10372. https://doi.org/10.1038/s41598-019-46828-y
Chung IM, Rajakumar G, Thiruvengadam M (2018a) Effect of silver nanoparticles on phenolic compounds production and biological activities in hairy root cultures of Cucumis anguria. Acta Biol Hung 69:97–109. https://doi.org/10.1556/018.68.2018.1.8
Chung IM, Rekha K, Rajakumar G, Thiruvengadam M (2018b) Influence of silver nanoparticles on the enhancement and transcriptional changes of glucosinolates and phenolic compounds in genetically transformed root cultures of Brassica rapa ssp. rapa. Bioprocess Biosyst Eng 41(11):1665–1677. https://doi.org/10.1007/s00449-018-1991-3
Cvjetko P, Zovko M, ŠTefanić PP, Biba R, Tkalec M, Domijan AM, Vrček IV, Letofsky-Papst I, ŠIkić S, Balen B (2017) Phytotoxic effects of silver nanoparticles in tobacco plants. Environ Sci Pollut Res 25(6):5590–5602. https://doi.org/10.1007/s11356-017-0928-8
De M, Ghosh PS, Rotello VM (2008) Applications of nanoparticles in biology. Adv Mater 20:4225–4241. https://doi.org/10.1002/adma.200703183
Ealia SAM, Saravanakumar MP (2017) A review on the classification, characterisation, synthesis of nanoparticles and their application. IOP Conf Ser Mater Sci Eng 263:032019. https://doi.org/10.1088/1757-899X/263/3/032019
Ejaz M, Raja NI, Mashwani ZUR, Ahmad MS, Hussain M, Iqbal M (2018) Effect of silver nanoparticles and silver nitrate on growth of rice under biotic stress. IET Nanobiotechnol 12:927–932. https://doi.org/10.1049/iet-nbt.2018.0057
El-Kosary S, Abd Allatif AM, Stino RG, Hassan MM, Kinawy AA (2020) Effect of silver nanoparticles on micropropagation of Date Palm (Phoenix Dactylifera L, Cv Sewi And Medjool). Plant Arch 20(2):9701–9706
El-Temsah YS, Joner EJ (2012) Impact of Fe and Ag nanoparticles on seed germination and differences in bioavailability during exposure in aqueous suspension and soil. Environ Toxicol 27:42–49. https://doi.org/10.1002/tox.20610
Evlakov PM, Fedorova OA, Grodetskaya TA, Zakharova OV, Gusev AA, Krutyakov YA, Baranov OY (2020) Influence of copper oxide and silver nanoparticles on microclonal sprouts of Downy Birch (Betula pubescens Ehrh.). Nanotechnol Russia 15(7–8):476–482. https://doi.org/10.1134/s1995078020040035
Ewais EA, Desouky SA, Elshazly EH (2015) Evaluation of callus responses of Solanum nigrum L. exposed to biologically synthesized silver nanoparticles. Nanosci Nanotechnol 5:45–56. https://doi.org/10.5923/j.nn.20150503.01
Fakhrfeshani M, Bagheri A, Sharifi A (2012) Disinfecting effects of nano silver fluids in Gerbera (Gerbera jamesonii) Capitulum tissue culture. J Biol Environ Sci 6:121–127
Fazal H, Abbasi BH, Ahmad N, Ali M (2016) Elicitation of medicinally important antioxidant secondary metabolites with silver and gold nanoparticles in callus cultures of Prunella vulgaris L. Appl Biochem Biotechnol 180:1076–1092. https://doi.org/10.1007/s12010-016-2153-1
Garibo D, Borbón-Nuñez HA, de León JND, Mendoza EG, Estrada I, Toledano-Magaña Y, Tiznado H, Ovalle-Marroquin M, Soto-Ramos AG, Blanco A, Rodríguez JA, Romo OA, Chávez-Almazán LA, Susarrey-Arce A (2020) Green synthesis of silver nanoparticles using Lysiloma acapulcensis exhibit high-antimicrobial activity. Sci Rep 10:12805. https://doi.org/10.1038/s41598-020-69606-7
Golkar P, Moradi M, Garousi GA (2019) Elicitation of stevia glycosides using salicylic acid and silver nanoparticles under callus culture. Sugar Tech 21:569–577. https://doi.org/10.1007/s12355-018-0655-6
Gorczyca A, Pociecha E, Kasprowicz M, Niemiec M (2015) Effect of nanosilver in wheat seedlings and Fusarium culmorum culture systems. Eur J Plant Pathol 142:251–261. https://doi.org/10.1007/s10658-015-0608-9
Gouran A, Jirani M, Mozafari AA, Saba MK, Ghaderi N, Zaheri S (2014) Effect of silver nanoparticles on grapevine leaf explants sterilization at in vitro conditions. In: 2nd national conference on nanotechnology from theory to application, Isfahan, Iran, vol 20, pp 1–6
Govorov AO, Carmeli I (2007) Hybrid structures composed of photosynthetic system and metal nanoparticles: plasmon enhancement effect. Nano Lett 7:620–625. https://doi.org/10.1021/nl062528t
Guilger-Casagrande M, Lima R (2019) Synthesis of silver nanoparticles mediated by fungi: a review. Front Bioeng Biotechnol 7:287. https://doi.org/10.3389/fbioe.2019.00287
Gupta D, Chauhan P (2017) Green synthesis of silver nanoparticles involving extract of plants of different taxonomic groups. J Nanomed Res 5:00110. https://doi.org/10.15406/jnmr.2017.05.00110
Gupta N, Upadhyaya CP, Singh A, Abd-Elsalam KA, Prasad R (2018) Applications of silver nanoparticles in plant protection. In: Abd-Elsalam K, Prasad R (eds) Nanobiotechnology applications in plant protection. Nanotechnology in the life sciences. Springer, Cham. https://doi.org/10.1007/978-3-319-91161-8_9
Gurunathan S, Han JW, Kim ES, Park JH, Kim JH (2015) Reduction of graphene oxide by resveratrol: a novel and simple biological method for the synthesis of an effective anticancer nanotherapeutic molecule. Int J Nanomed 10:2951–2969. https://doi.org/10.2147/IJN.S79879
Hamouda RA, Hussein MH, Abo-elmagd RA, Bawazir SS (2019) Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica. Sci Rep 9:13071. https://doi.org/10.1038/s41598-019-49444-y
Harish KK, Nagasamy V, Himangshu B, Anuttam K (2018) Metallic nanoparticle: a review. Biomed J Sci Tech Res 4:3765–3775. https://doi.org/10.26717/BJSTR.2018.04.001011
Hasan S (2015) A review on nanoparticles: their synthesis and types. Res J Recent Sci 4:1–3
Hasan M, Mehmood K, Mustafa G, Zafar A, Tariq T, Hassan SG, Loomba S, Zia M, Mazher A, Mahmood N, Shu X (2021) Phytotoxic evaluation of phytosynthesized silver nanoparticles on lettuce. Coatings 11(2):225. https://doi.org/10.3390/coatings11020225
Hashim K, Salih A (2014) The effect of (AgNO3) NPs on increasing of secondary metabolites of Calendula officinalis L. in vitro. Int J Pharm Therap 5:267–272
Hojjat S, Hojjat H (2015) Effect of nano silver on seed germination and seedling growth in fenugreek seed. Int J Food Eng 1:106–110. https://doi.org/10.18178/ijfe.1.2.106-110
Homaee MB, Ehsanpour AA (2015) Physiological and biochemical responses of potato (Solanum tuberosum) to silver nanoparticles and silver nitrate treatments under in vitro conditions. Ind J Plant Physiol 20:353–359. https://doi.org/10.1007/s40502-015-0188-x
Homaee MB, Ehsanpour AA (2016) Silver nanoparticles and silver ions: Oxidative stress responses and toxicity in potato (Solanum tuberosum L) grown in vitro. Hortic Environ Biotechnol 57:544–553. https://doi.org/10.1007/s13580-016-0083-z
Ibrahim E, Fouad H, Zhang M, Zhang Y, Qiu W, Yan C, Li B, Mo J, Chen J (2019) Biosynthesis of silver nanoparticles using endophytic bacteria and their role in inhibition of rice pathogenic bacteria and plant growth promotion. RSC Adv 9:29293–29299. https://doi.org/10.1039/C9RA04246F
Jadczak P, Kulpa D, Bihun M, Przewodowski W (2019) Positive effect of AgNPs and AuNPs in in vitro cultures of Lavandula angustifolia Mill. Plant Cell Tissue Organ Cult 139:191–197. https://doi.org/10.1007/s11240-019-01656-w
Jadczak P, Kulpa D, Drozd R, Przewodowski W, Przewodowska A (2020) Effect of AuNPs and AgNPs on the antioxidant system and antioxidant activity of lavender (Lavandula angustifolia Mill.) from in vitro cultures. Molecules 25(23):5511. https://doi.org/10.3390/molecules25235511
Jamshidi M, Ghanati F (2017) Taxanes content and cytotoxicity of hazel cells extract after elicitation with silver nanoparticles. Plant Physiol Biochem 110:178–184. https://doi.org/10.1016/j.plaphy.2016.04.026
Jamshidi M, Ghanati F, Rezaei A, Bemani E (2016) Change of antioxidant enzymes activity of hazel (Corylus avellana L.) cells by AgNPs. Cytotechnology 68:525–530. https://doi.org/10.1007/s10616-014-9808-y
Jasim B, Thomas R, Mathew J, Radhakrishnan EK (2017) Plant growth and diosgenin enhancement effect of silver nanoparticles in Fenugreek (Trigonella foenum-graecum L.). Saudi Pharmaceutical Journal 25:443–447. https://doi.org/10.1016/j.jsps.2016.09.012
Jeevanandam J, Barhoum A, Chan YS, Dufresne A, Danquah MK (2018) Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations Beilstein J Nanotechnol 9:1050–1074. doi:https://doi.org/10.3762/bjnano.9.98
Jhanzab H, Razzaq A, Rehman A, Hafeez A, Yasmeen F (2015) Silver nano-particles enhance the growth, yield and nutrient use efficiency of wheat. Int J Agron Agric Res 7:15–22
Kaabipour S, Hemmati S (2021) A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures. Beilstein J Nanotechnol 12:102–136. https://doi.org/10.3762/bjnano.12.9
Kale SK, Parishwad GV, Husainy ASN, Patil AS (2021) Emerging agriculture applications of silver nanoparticles. FAF. https://doi.org/10.30919/esfaf438
Kalsaitkar P, Tanna J, Kumbhare A, Akre S, Warade C, Gandhare N (2014) Silver nanoparticles induced effect on in-vitro callus production in Bacopa monnieri. Asian J Biol Life Sci 3:167–172
Karuppanapandian T, Wang HW, Prabakaran N, Jeyalakshmi K, Kwon M, Manoharan K, Kim W (2011) 2, 4-dichlorophenoxyacetic acid-induced leaf senescence in mung bean (Vigna radiata L. Wilczek) and senescence inhibition by co-treatment with silver nanoparticles. Plant Physiol Biochem 49:168–177. https://doi.org/10.1016/j.plaphy.2010.11.007
Ke M, Li Y, Qu Q, Ye Y, Peijnenburg W, Zhang Z, Xu N, Lu T, Sun L, Qian H (2020) Offspring toxicity of silver nanoparticles to Arabidopsis thaliana flowering and floral development. J Hazard Mater 386:121975. https://doi.org/10.1016/j.jhazmat.2019.121975
Khan NA (2006) Ethylene action in plants. Springer, Berlin
Kim D, Gopal J, Sivanesan I (2017) Nanomaterials in plant tissue culture: the disclosed and undisclosed. RSC Adv 7:36492. https://doi.org/10.1039/C7RA07025J
Kokina I, Gerbreders V, Sledevskis E, Bulanovs A (2013) Penetration of nanoparticles in flax (Linum usitatissimum L.) calli and regenerants. J Biotechnol 165:127–132. https://doi.org/10.1016/j.jbiotec.2013.03.011
Kulkarni N, Muddapur U (2014) Biosynthesis of metal nanoparticles: a review. J Nanotechnol 2014:1–8. https://doi.org/10.1155/2014/510246
Kumari M, Mukherjee A, Chandrasekaran N (2009) Genotoxicity of silver nanoparticles in Allium cepa. Sci Total Environ 407:5243–5246. https://doi.org/10.1016/j.scitotenv.2009.06.024
Lade B, Shanware A (2020) Phytonanofabrication: methodology and factors affecting biosynthesis of nanoparticles. Smart Nanosyst Biomed Optoelectron Catal. https://doi.org/10.5772/intechopen.90918
Lamsa K, Kim SW, Jung JH, Kim YS, Kim KS, Lee YS (2011) Inhibition effects of silver nanoparticles against powdery mildews on cucumber and pumpkin. Mycobiology 39:26–32
Lee WM, Kwak JI, An YJ (2012) Effect of silver nanoparticles in crop plants Phaseolus radiatus and Sorghum bicolor: Media effect on phytotoxicity. Chemosphere 86(5):491–499. https://doi.org/10.1016/j.chemosphere.2011.10.013
Li C, Shuford KL, Park Q, Cai W, Li Y, Lee EJ, Cho SO (2007a) High-yield synthesis of single-crystalline gold nano-octahedra. Angew Chem Int Ed Engl 46:3264–3268. https://doi.org/10.1002/anie.200604167
Li S, Shen Y, **e A, Yu X, Qiu L, Zhang L, Zhang Q (2007b) Green synthesis of silver nanoparticles using Capsicum annuum L. extract. Green Chem 9:852–858. https://doi.org/10.1039/b615357g
Li M, Liu H, Dang F, Hintelmann H, Yin B, Zhou D (2020) Alteration of crop yield and quality of three vegetables upon exposure to silver nanoparticles in sludge-amended soil. ACS Sustain Chem Eng 8:2472–2480. https://doi.org/10.1021/acssuschemeng.9b06721
Ltd RAM (2021) Nanotechnology—global market trajectory & analytics. Research and Markets Ltd 2021. https://www.researchandmarkets.com/reports/338364/nanotechnology_global_market_trajectory_and
Ma X, Geiser-Lee J, Deng Y, Kolmakov A (2010) Interactions between engineered nanoparticles (ENPs) and plants: phytotoxicity, uptake and accumulation. Sci Total Environ 408:3053–3061. https://doi.org/10.1016/j.scitotenv.2010.03.031
Mafuné F, Kohno JY, Takeda Y, Kondow T, Sawabe H (2000) Formation and size control of silver nanoparticles by laser ablation in aqueous solution. J Phys Chem B 104:9111–9117. https://doi.org/10.1021/jp001336y
Mahendran D, Kavi Kishor PB, Geetha N, Venkatachalam P (2018) Phycomolecule-coated silver nanoparticles and seaweed extracts induced high-frequency somatic embryogenesis and plant regeneration from Gloriosa superba L. J Appl Phycol 30:1425–1436. https://doi.org/10.1007/s10811-017-1293-1
Mahna N, Vahed SZ, Khani S (2013) Plant in vitro culture goes nano: nanosilver-mediated decontamination of ex vitro explants. J Nanomed Nanotechol 4:161. https://doi.org/10.4172/2157-7439.1000161
Mallick K, Witcomb MJ, Scurrell MS (2004) Polymer stabilized silver nanoparticles: A photochemical synthesis route. J Mater Sci 39:4459–4463. https://doi.org/10.1023/B:JMSC.0000034138.80116.50
Manh Cuong D, Du Cong P, Tung HT, Ngan HTM, Luan VQ, Phong TH, Khai HD, Phuong TTB, Nhut DT (2021) Silver nanoparticles as an effective stimulant in micropropagation of Panax vietnamensis—a valuable medicinal plant. Plant Cell Tiss Organ Cult 146:577–588. https://doi.org/10.1007/s11240-021-02095-2
Manickavasagam M, Pavan G, Vasudevan V (2019) A comprehensive study of the hormetic influence of biosynthesized AgNPs on regenerating rice calli of indica cv. IR64. Sci Rep 9:8821. https://doi.org/10.1038/s41598-019-45214-y
Marslin G, Sheeba CJ, Franklin G (2017) Nanoparticles alter secondary metabolism in plants via ROS burst. Front Plant Sci 8:1–8. https://doi.org/10.3389/fpls.2017.00832
Mazumdar H (2014) The impact of silver nanoparticles on plant biomass and chlorophyll content. Res Inventy 4:12–20
Mazumdar H, Ahmed GU (2011) Synthesis of silver nanoparticles and its adverse effect on seed germinations in Oryza sativa, Vigna radiata and Brassica campestris. Int J Adv Biotechnol Res 2:404–413
Mirzajani F, Askari H, Hamzelou S, Farzaneh M, Ghassempour A (2013) Effect of silver nanoparticles on Oryza sativa L. and its rhizosphere bacteria. Ecotoxicol Environ Saf 88:48–54. https://doi.org/10.1016/j.ecoenv.2012.10.018
Mishra V, Mishra RK, Dikshit A, Pandey AC (2014) Interactions of nanoparticles with plants: an emerging prospective in the agriculture industry. In: Emerging technologies and management of crop stress tolerance, vol 1. Academic Press, pp 159–180
Mohanraj VJ, Chen Y (2006) Nanoparticles—a review. Trop J Pharm Res 5:561–573. https://doi.org/10.4314/tjpr.v5i1.7
Moola AK, Senthil Kumar T, Ranjitha Kumari BD (2021) Enhancement of Celastrol compound by silver nanoparticles and acetosyringone in Celastrus paniculatus Willd. through adventitious and hairy root culture. J Plant Biochem Biotechnol. https://doi.org/10.1007/s13562-021-00676-y
Mousavi SR, Rezaei M (2011) Nanotechnology in agriculture and food production. J Appl Environ Biol Sci 1:414–419
Mufamadi MS, Mulaudzi RB (2019) Green engineering of silver nanoparticles to combat plant and foodborne pathogens: potential economic impact and food quality. Plant Nanobionics 451(476):451–476. https://doi.org/10.1007/978-3-030-16379-2_16
Mustafa HS, Oraibi AG, Ibrahim KM, Ibrahim NK (2017) Influence of silver and copper nanoparticles on physiological characteristics of Phaseolus vulgaris L. in vitro and in vivo. Int J Curr Microbiol App Sci 6:834–843. https://doi.org/10.20546/ijcmas.2017.601.098
Nair PMG, Chung IM (2015) Physiological and molecular level studies on the toxicity of silver nanoparticles in germinating seedlings of mung bean (Vigna radiata L.). Acta Physiol Plant 37:1719. https://doi.org/10.1007/s11738-014-1719-1
Nartop P (2016) Green sterilization of Rosmarinus officinalis L. stem surfaces with silver nanoparticles synthesized using Rubia tinctorum L. cell culture extracts. Iran J Sci Technol Trans Sci 42(2):411–414. https://doi.org/10.1007/s40995-016-0065-0
Ngan HTM, Cuong DM, Tung HT, Nghiep ND, Le BV, Nhut DT (2020) The effect of cobalt and silver nanoparticles on overcoming leaf abscission and enhanced growth of rose (Rosa hybrida L. ‘Baby Love’) plantlets cultured in vitro. Plant Cell Tissue Org Cult 141:393–405. https://doi.org/10.1007/s11240-020-01796-4
Opoku G, Davies FM, Zetrio EV, Camble EE (1996) Relationship between seed vigor and yield of white beans (Phaseolos vulgaris L.). Plant Var Seeds 9:119–125
Pallavi CM, Srivastava R, Arora S, Sharma AK (2016) Impact assessment of silver nanoparticles on plant growth and soil bacterial diversity. 3 Biotech 6:1–10. https://doi.org/10.1007/s13205-016-0567-7
Parzymies M (2021) Nano-silver particles reduce contaminations in tissue culture but decrease regeneration rate and slows down growth and development of Aldrovanda vesiculosa Explants. Appl Sci 11:3653. https://doi.org/10.3390/app11083653
Parzymies M, Pudelska K, Poniewozik M (2019) The use of nano-silver for disinfection of Pennisetum alopecuroides plant material for tissue culture. Acta Sci Pol Hortorum Cultus 18:127–135. https://doi.org/10.24326/asphc.2019.3.12
Patlolla AK, Berry A, May L, Tchounwou PB (2012) Genotoxicity of silver nanoparticles in Vicia faba: a pilot study on the environmental monitoring of nanoparticles. Int J Environ Res Public Health 9:1649–1662. https://doi.org/10.3390/ijerph9051649
Pittol M, Tomacheski D, Simões DN, Ribeiro VF, Santana RMC (2017) Macroscopic effects of silver nanoparticles and titanium dioxide on edible plant growth. Environ Nanotechnol Monit Manag 8:127–133. https://doi.org/10.1016/j.enmm.2017.07.003
Pokhrel L, Dubey B (2013) Evaluation of developmental responses of two crop plants exposed to silver and zinc oxide nanoparticles. Sci Total Environ 452–453:321–332. https://doi.org/10.1016/j.scitotenv.2013.02.059
Quardos ME, Mar LC (2010) Environmental and human health risks of aerosolized silver nano particles. J Air Waste Manag Assoc 60:770–781. https://doi.org/10.3155/1047-3289.60.7.770
Radchuk V, Borisjuk L (2014) Physical, metabolic and developmental functions of the seed coat. Front Plant Sci 5:510. https://doi.org/10.3389/fpls.2014.00510
Ramezannezhad R, Aghdasi M, Fatemi M (2019) Enhanced production of cichoric acid in cell suspension culture of Echinacea purpurea by silver nanoparticle elicitation. Plant Cell Tissue Organ Cult 139(2):261–273. https://doi.org/10.1007/s11240-019-01678-4
Rostami AA, Shahsavar A (2009) Nano-silver particles eliminate the in vitro contaminations of olive ‘mission’ explants. Asian J Plant Sci 8:505–509
Sadak MS (2019) Impact of silver nanoparticles on plant growth, some biochemical aspects, and yield of fenugreek plant (Trigonella foenum-graecum). Bull Natl Res Cent 43:1–6. https://doi.org/10.1186/s42269-019-0077-y
Safavi K (2012) Evaluation of using nanomaterial in tissue culture media and biological activity. In: 2nd international conference on ecological, environmental and biological sciences (EEBS'2012), Bali, Indonesia, pp 5–8
Saha N, Gupta SD (2018) Promotion of shoot regeneration of Swertia chirata by biosynthesized silver nanoparticles and their involvement in ethylene interceptions and activation of antioxidant activity. Plant Cell Tiss Organ Cult 134:289–300. https://doi.org/10.1007/s11240-018-1423-8
Samanta S, Agarwal S, Nair KK, Harris RA, Swart H (2019) Biomolecular assisted synthesis and mechanism of silver and gold nanoparticles. Mater Res Express 6:082009. https://doi.org/10.1088/2053-1591/ab296b
Sarabi M, Safipour Afshar A, Mahmoodzadeh H (2015) Physiological analysis of silver nanoparticles and AgNO3 effect to Brassica napus L. J Chem Health Risks 5:285–294
Sarmast MK, Salehi H (2016) Silver nanoparticles: an influential element in plant nanobiotechnology. Mol Biotechnol 58:441–449. https://doi.org/10.1007/s12033-016-9943-0
Sarmast MK, Salehi H, Khosh-Khui M (2011) Nano silver treatment is effective in reducing bacterial contaminations of Araucaria Excelsa R. Br. var. glauca explants. Acta Biol Hung 62:477–484. https://doi.org/10.1556/ABiol.62.2011.4.12
Sarmast MK, Niazi A, Salehi H, Abolimoghadam A (2015) Silver nanoparticles affect ACS expression in Tecomella undulata in vitro culture. Plant Cell Tissue Organ Cult 121:227–236. https://doi.org/10.1007/s11240-014-0697-8
Savithramma N, Ankanna S, Bhumi G (2012) Effect of nanoparticles on seed germination and seedling growth of Boswellia Ovalifoliolata—an endemic and endangered medicinal tree taxon. Nano vis 2:61–68
Sehnal K, Hosnedlova B, Docekalova M, Stankova M, Uhlirova D, Tothova Z, Kepinska M, Milnerowicz H, Fernandez C, Ruttkay-Nedecky B, Nguyen HV, Ofomaja A, Sochor J, Kizek R (2019) An assessment of the effect of green synthesized silver nanoparticles using sage leaves (Salvia officinalis L.) on germinated plants of maize (Zea mays L.). Nanomaterials 9:1550. https://doi.org/10.3390/nano9111550
Seif SM, Sorooshzadeh A, Rezazadeh HS, Naghdibadi HA (2011) Effect of nano silver and silver nitrate on seed yield of borage. J Med Plants Res 5:706–710
Selivanov NY, Selivanova OG, Sokolov OI, Sokolova MK, Sokolov AO, Bogatyrev VA, Dykman LA (2017) Effect of gold and silver nanoparticles on the growth of the Arabidopsis thaliana cell suspension culture. Nanotechnol Russia 12:116–124. https://doi.org/10.1134/S1995078017010104
Shakeran Z, Keyhanfar M, Asghari G, Ghanadian M (2015) Improvement of atropine production by different biotic and abiotic elicitors in hairy root cultures of Datura metel. Turk J Biol 39:111–118. https://doi.org/10.3906/biy-1405-25
Shapira P, Youtie J (2015) The economic contributions of nanotechnology to green and sustainable growth. Green Process Nanotechnol. https://doi.org/10.1007/978-3-319-15461-9_15
Sharma P, Bhatt D, Zaidi MG, Saradhi PP, Khanna PK, Arora S (2012) Silver nanoparticle-mediated enhancement in growth and antioxidant status of Brassica juncea. Appl Biochem Biotechnol 167:2225–2233. https://doi.org/10.1007/s12010-012-9759-8
Sharshir SW, Ismail M, Kandeal A, Baz FB, Eldesoukey A, Younes M (2021) Improving thermal, economic, and environmental performance of solar still using floating coal, cotton fabric, and carbon black nanoparticles. Sustain Energy Technol Assess 48:101563. https://doi.org/10.1016/j.seta.2021.101563
Shokri S, Babaei A, Ahmadian M, Hessami S, Arab MM (2014) The effects of different concentrations of Nano-silver on elimination of bacterial contaminations and phenolic exudation of Rose (Rosa hybrida L.) in vitro culture. Int J Farm Alli Sci 3:50–54. https://doi.org/10.17660/ActaHortic.2015.1083.49
Siddiqi KS, Husen A (2021) Plant response to silver nanoparticles: a critical review. Crit Rev Biotechnol. https://doi.org/10.1080/07388551.2021.1975091
Sillen W, Thijs S, Abbamondi GR, Janssen J, Weyens N, White J, Vangronsveld J (2015) Effects of silver nanoparticles on soil microorganisms and maize biomass are linked in the rhizosphere. Soil Biol Biochem 91:14–22. https://doi.org/10.1016/j.soilbio.2015.08.019
Singh A, Singh NB, Hussain I, Singh H, Singh SC (2015) Plant-nanoparticle interaction: an approach to improve agricultural practices and plant productivity. Int J Pharm Sci Invent 4:25–40
Singh AK, Rathod V, Singh D, Mathew J, Kulkarni P (2016) Effect of silver nanoparticles (AgNps) produced by an endophytic fungus Fusarium Semitectum isolated from a medicinal plant Withania Somnifera (Ashwagandha) on seed germination. IJRSAS 2:6–12. https://doi.org/10.20431/2454-6224.0205002
Singh RP, Handa R, Manchanda G (2021) Nanoparticles in sustainable agriculture: an emerging opportunity. J Control Release 329:1234–1248. https://doi.org/10.1016/j.jconrel.2020.10.051
Spinoso-Castillo JL, Chavez-Santoscoy RA, Bogdanchikova N, Perez-Sato JA, Morales-Ramos V, Bello-Bello JJ (2017) Antimicrobial and hormetic effects of silver nanoparticles on in vitro regeneration of vanilla (Vanilla planifolia Jacks Ex Andrews) using a temporary immersion system. Plant Cell Tissue Organ Cult 129:195–207. https://doi.org/10.1007/s11240-017-1169-8
Srivastava LM (2002) Chapter 19—seed germination, mobilization of food reserves, and seed dormancy. In: Plant growth and development. Academic Press, pp 447–471. https://doi.org/10.1016/B978-012660570-9/50161-1
Syu YY, Hung JH, Chen JC, Chuang HW (2014) Impacts of size and shape of silver nanoparticles on Arabidopsis plant growth and gene expression. Plant Physiol Biochem 83:57–64. https://doi.org/10.1016/j.plaphy.2014.07.010
Taghizadeh M, Solgi M (2014) The application of essential oils and silver nanoparticles for sterilization of bermudagrass explants in in vitro culture. Int J Hort Sci Technol 1:131–140
Thangavelu RM, Gunasekaran D, Jesse MI, S.U MR, Sundarajan D, Krishnan K (2018) Nanobiotechnology approach using plant rooting hormone synthesized silver nanoparticle as “nanobullets” for the dynamic applications in horticulture—an in vitro and ex vitro study. Arab J Chem 11(1):48–61. https://doi.org/10.1016/j.arabjc.2016.09.022
Timoteo CO, Paiva R, Dos Reis MV, Claro PIC, Ferraz LM, Marconcini JM, de Oliveira JE (2019) In vitro growth of Physalis peruviana L. affected by silver nanoparticles. 3 Biotech 9:145. https://doi.org/10.1007/s13205-019-1674-z
Tripathi DK, Tripathi A, Shweta Singh S, Singh Y, Vishwakarma K, Yadav G, Sharma S, Singh VK, Mishra RK, Upadhyay RG, Dubey NK, Lee Y, Chauhan DK (2017) Uptake, accumulation and toxicity of silver nanoparticle in autotrophic plants, and heterotrophic microbes: a concentric review. Front Microbiol 8:7. https://doi.org/10.3389/fmicb.2017.00007
Tung HT, Thuong TT, Cuong DM, Luan VQ, Hien VT, Hieu T, Nam NB, Phuong HTN, van The VB, Khai HD, Nhut DT (2021a) Silver nanoparticles improved explant disinfection, in vitro growth, runner formation and limited ethylene accumulation during micropropagation of strawberry (Fragaria × ananassa). Plant Cell Tissue Organ Cult 145(2):393–403. https://doi.org/10.1007/s11240-021-02015-4
Tung HT, Bao HG, Cuong DM, Ngan HTM, Hien VY, Luan VQ, Vinh BVT, Phuong HTN, Nam NB, Trieu LN, Truong NK, Hoang PND, Nhut DT (2021b) Silver nanoparticles as the sterilant in large-scale micropropagation of chrysanthemum. In Vitro Cell Dev Biol Plant. https://doi.org/10.1007/s11627-021-10163-7
Tymoszuk A (2021) Silver nanoparticles effects on in vitro germination, growth, and biochemical activity of tomato, radish, and kale seedlings. Materials 14(18):5340. https://doi.org/10.3390/ma14185340
Tymoszuk A, Miler N (2019) Silver and gold nanoparticles impact on in vitro adventitious organogenesis in chrysanthemum, gerbera and Cape Primrose. Sci Hortic 257:108766. https://doi.org/10.1016/j.scienta.2019.108766
Usman M, Farooq M, Wakeel A, Nawaz A, Cheema SA, Rehman HU, Ashraf I, Sanaullah M (2020) Nanotechnology in agriculture: current status, challenges and future opportunities. Sci Total Environ 721:137778. https://doi.org/10.1016/j.scitotenv.2020.137778
Vannini C, Domingo G, Onelli E, Prinsi B, Marsoni M, Espen L, Bracale M (2013) Morphological and proteomic responses of Eruca sativa exposed to silver nanoparticles or silver nitrate. PLoS ONE 8:e68752. https://doi.org/10.1371/journal.pone.0068752
Vasyukova I, Gusev A, Zakharova O, Baranchikov P, Yevtushenko N (2021) Silver nanoparticles for enhancing the efficiency of micropropagation of gray poplar (Populus × canescens Aiton. Sm.). OP Conf Ser 875(1):012053. https://doi.org/10.1088/1755-1315/875/1/012053
Venkatachalam P, Malar S, Thiyagarajan M, Indiraarulselvi P, Geetha N (2017) Effect of phycochemical coated silver nanocomplexes as novel growth-stimulating compounds for plant regeneration of Alternanthera sessilis L. J Appl Phycol 29:1095–1106. https://doi.org/10.1007/s10811-016-0977-2
Waterworth WM, Bray CM, West CE (2015) The importance of safeguarding genome integrity in germination and seed longevity. J Exp Bot 66:3549–3558. https://doi.org/10.1093/jxb/erv080
Wesołowska A, Jadczak P, Kulpa D, Przewodowski W (2019) Gas chromatography-mass spectrometry (GC-MS) analysis of essential oils from AgNPs and AuNPs elicited Lavandula angustifolia in vitro cultures. Molecules 24(3):606. https://doi.org/10.3390/molecules24030606
Yan A, Chen Zhong C (2019) Impacts of silver nanoparticles on plants: a focus on the phytotoxicity and underlying mechanism. Int J Mol Sci 20:1003. https://doi.org/10.3390/ijms20051003
Yasur J, Rani PU (2013) Environmental effects of nanosilver: impact on castor seed germination, seedling growth, and plant physiology. Environ Sci Pollut Res Int 20:8636–8648. https://doi.org/10.1007/s11356-013-1798-3
Yin L, Cheng Y, Espinasse B, Colman BP, Auffan M, Wiesner M, Rose J, Liu J, Bernhardt ES (2011) More than the ions: the effects of silver nanoparticles on Lolium multiflorum. Environ Sci Technol 45:2360–2367. https://doi.org/10.1021/es103995x
Zahir A, Nadeem M, Ahmad W, Nathalie G, Hano C, Abbasi BH (2019) Chemogenic silver nanoparticles enhance lignans and neolignans in cell suspension cultures of Linum usitatissimum L. Plant Cell Tissue Organ Cult 136:589–596. https://doi.org/10.1007/s11240-018-01539-6
Zakharova O, Vasyukova I, Strekalova N, Gusev A (2019) Effects of silver nanoparticles on morphometric parameters of hairy birch (Betula pubescens) at various stages of micro cloning. OP Conf Ser 392(1):012024. https://doi.org/10.1088/1755-1315/392/1/012024
Zhang C, Yan Q, Cheuk W, Wu J (2004) Enhancement of tanshinone production in Salvia miltiorrhiza hairy root culture by Ag+elicitation and nutrient feeding. Planta Med 70(2):147–151. https://doi.org/10.1055/s-2004-815492
Zhang Q, Li N, Goebl J, Lu ZD, Yin YD (2011) A systematic study of the synthesis of silver nanoplates: Is citrate a “Magic” Reagent? J Am Chem Soc 133:18931–18939. https://doi.org/10.1021/ja2080345
Zhang B, Zheng LP, Li WY, Wang JW (2013) Stimulation of artemisinin production in Artemisia annua hairy roots by Ag-SiO2 core-shell nanoparticles. Curr Nanosci 9:363–370. https://doi.org/10.2174/1573413711309030012
Zhang XF, Liu ZG, Shen W, Gurunathan S (2016) Silver nanoparticles: synthesis, characterization, properties, applications, and therapeutic approaches. Int J Mol Sci 17:1534. https://doi.org/10.3390/ijms17091534
Zheng Y, Hou L, Liu M, Newell SE, Yin G, Yu C, Zhang H, Li X, Gao D, Gao J, Wang R, Liu C (2017) Effects of silver nanoparticles on nitrification and associated nitrous oxide production in aquatic environments. Sci Adv 3:e1603229. https://doi.org/10.1126/sciadv.1603229
Zhu JJ, Liao XH, Zhao XN, Chen HY (2001) Preparation of silver nanorods by electrochemical methods. Mater Lett 49:91–95. https://doi.org/10.1016/S0167-577X(00)00349-9
Zia M, Yaqoob K, Mannan A, Nisa S, Raza G, Rehman RU (2019) Regeneration response of carnation cultivars in response of silver nanoparticles under in vitro conditions. Vegetos 33(1):11–20. https://doi.org/10.1007/s42535-019-00074-9
Zuverza-Mena N, Armendariz R, Peralta-Videa JR, Gardea-Torresdey JL (2016) Effects of silver nanoparticles on radish sprouts: root growth reduction and modifications in the nutritional value. Front Plant Sci 7:90. https://doi.org/10.3389/fpls.2016.00090
Bello-Bello JJ, Chavez-Santoscoy RA, Lecona-Guzmán CA, Bogdanchikova N, Salinas-Ruíz J, Gómez-Merino FC, Pestryakov A (2017) Hormetic Response by Silver Nanoparticles on In Vitro Multiplication of Sugarcane (Saccharum spp. Cv. Mex 69-290) Using a Temporary Immersion System. Dose Response. 15. https://doi.org/10.1177/1559325817744945.
Acknowledgements
The authors would like to express their gratitude to the staff of Kelkar Education Trust’s Scientific Research Centre for their support.
Funding
The authors did not receive funding as assistance for the preparation of this manuscript.
Author information
Authors and Affiliations
Contributions
SM conducted extensive literature review and drafted the sections on effect of silver nanoparticles on in-vitro seed germination and plant growth. JK conducted extensive literature review and drafted the section on the mechanism of action of silver nanoparticles. PD conducted extensive literature review and drafted the section on effect of silver nanoparticles on in-vitro metabolite production in plants. SB provided his expertise in Plant Biotechnology and assisted SK in structuring the manuscript and designing the layout of the review article. As the corresponding author of the review article, SK designed the layout of the manuscript in concordance with SB. Further, she prudently checked every detail written and reviewed by the co-authors and structured the final manuscript.
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Communicated by Mohammad Faisal.
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Mahajan, S., Kadam, J., Dhawal, P. et al. Application of silver nanoparticles in in-vitro plant growth and metabolite production: revisiting its scope and feasibility. Plant Cell Tiss Organ Cult 150, 15–39 (2022). https://doi.org/10.1007/s11240-022-02249-w
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11240-022-02249-w