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Use of Micellar Electrokinetic Chromatography to Analyze Sesquiterpene Lactones from Laurus nobilis L.

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Pharmaceutical Chemistry Journal Aims and scope

A micellar electrokinetic chromatographic method for quantitative determination of sesquiterpene lactones (costunolide and dehydrocostuslactone) from Laurus nobilis leaves was developed. It was shown that urea had to be added to the leading electrolyte in order to increase the analysis selectivity. The developed method was used to establish the costunolide and dehydrocostuslactone contents in various leaf samples as 0.5757 and 0.0399%, respectively, calculated per absolute dry raw material. The main validation characteristics of the developed method were also determined.

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Authors and Affiliations

  1. Pyatigorsk Medical Pharmaceutical Institute, Branch of Volgograd State Medical University, Pyatigorsk, Stavropol Krai, 357532, Russia

    S. P. Senchenko, N. M. Nasukhova, L. A. Agova & D. A. Konovalov

Authors
  1. S. P. Senchenko
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  2. N. M. Nasukhova
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  3. L. A. Agova
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  4. D. A. Konovalov
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 50, No. 5, pp. 39 – 41, May, 2016.

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Senchenko, S.P., Nasukhova, N.M., Agova, L.A. et al. Use of Micellar Electrokinetic Chromatography to Analyze Sesquiterpene Lactones from Laurus nobilis L.. Pharm Chem J 50, 320–322 (2016). https://doi.org/10.1007/s11094-016-1444-8

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  • DOI: https://doi.org/10.1007/s11094-016-1444-8

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