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Effect of white-to-white corneal diameter on biomechanical indices assessed by Pentacam Scheimpflug corneal tomography and corneal visualization Scheimpflug technology

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Abstract

Purpose

To provide evidence for more accurate evaluation of refractive surgery candidates in clinics, this retrospective study investigated the effect of corneal diameter on the biomechanical indices assessed by Pentacam Scheimpflug cornea tomography (Pentacam) and corneal visualization Scheimpflug technology (Corvis ST).

Methods

The relevant data were collected of 132 eyes from 132 participants with moderate myopia who were candidates for refractive surgery. Eligible participants were apportioned to 2 groups based on the white-to-white (WTW) corneal diameter: Group A, ≤ 11.5 mm, and Group B, ≥ 11.6 mm. A single clinician performed Pentacam and Corvis ST imaging on each subject for 3 consecutive measurements, and the means were used for statistical analyses.

Results

Each group comprised 66 eyes. As measured by Pentacam, the 2 groups were comparable regarding Df and Da. For other measurements, Group A had significantly higher K1, K2, Db, Dp, Dt, Do, PPImin, PPImax, PPIavg, while Group B had significantly higher CCT, BFSf, BFSb, and ARTmax. Corvis ST data included DA ratio, SPA1, CBI, TBI, and ARTh. Only the latter showed a significant difference, with ARTh of group A (437.04 ± 76.60) larger than group B (470.46 ± 103.36, p = 0.04).

Conclusion

In a Chinese population, WTW corneal diameter showed effect on biomechanical indices assessed by Pentacam and Corvis ST. Personalized evaluation of these measurements based on corneal diameter should improve the sensitivity and specificity for screening of keratoconus by these devices.

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Data availability and material

The datasets generated and analyzed during the present study are available from the corresponding author on reasonable request.

Abbreviations

ARTh:

Ambrósio relational thickness to the horizontal profile

ARTmax:

Maximum Ambrósio relational thickness

BAD:

Belin/Ambrósio enhanced ectasia display

BFSb:

Best-fit sphere of the posterior surface of the cornea

BFSf:

Best-fit sphere of the anterior surface of the cornea

CBI:

Corneal biomechanical index

CCT:

Central corneal thickness

Corvis ST:

Corneal visualization Scheimpflug technology

Da:

Ambrósio′s relational thickness maximum

DA:

Deformation amplitude

Db:

Back elevation difference map

Df:

Front elevation difference map

Do:

Deviation overall

Dp:

Pachymetric progression index

Dt:

Minimum thickness

K1:

Keratometry in flat meridian

K2:

Keratometry in steep meridian

KC:

Keratoconus

LVC:

Laser vision correction

Pentacam:

Pentacam Scheimpflug cornea tomography

SPA1:

Stiffness parameter at first applanation

TBI:

Tomographic and biomechanical index

PPIavg:

Average pachymetric progression index

PPImax:

Maximum average pachymetric progression index

PPImin:

Minimum average pachymetric progression index

WTW:

White-to-white

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Authors and Affiliations

  1. Department of Refractive Surgery, Hefei Bright Eye Hospital, No. 299 Feixi Road, Hefei, 230000, China

    Qinghong Lin & Zhengwei Shen

Authors
  1. Qinghong Lin
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  2. Zhengwei Shen
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Contributions

QL conceived and designed research; QL and ZS collected data and conducted research; QL analyzed and interpreted data; QL wrote the initial paper; ZS revised the paper; ZS had primary responsibility for final content. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Zhengwei Shen.

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The authors declare that they have no conflicts of interest.

Ethical approval

The study protocol adhered to the tenets of the Declaration of Helsinki and was approved by the ethics committee of Shanghai Bright Eye Hospital, Shanghai, China. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Written informed consent was obtained from all individual participants included in the study.

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Lin, Q., Shen, Z. Effect of white-to-white corneal diameter on biomechanical indices assessed by Pentacam Scheimpflug corneal tomography and corneal visualization Scheimpflug technology. Int Ophthalmol 42, 1537–1543 (2022). https://doi.org/10.1007/s10792-021-02144-x

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  • DOI: https://doi.org/10.1007/s10792-021-02144-x

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