A new isochroman analogue, named monascuspilorin (1), was obtained from the n-BuOH-soluble fraction of the 95% EtOH extract of red mold rice fermented with the fungus Monascus pilosus BCRC 38072 (Eurotiaceae). The structure of the new compound was elucidated by comprehensive spectroscopic analysis, especially HR-ESI-MS and NMR experiments.
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs10600-017-1907-5/MediaObjects/10600_2017_1907_Fig1_HTML.gif)
Similar content being viewed by others
References
R. E. Mudgett, Monascus, in: Natural Food Colorants: Science and Technology, G. J. Lauro, F. J. Francis (eds.), Marcel Dekker, New York, 2000, p. 31.
J. Ma, Y. Li, Q. Ye, J. Li, Y. Hua, D. Ju, D. Zhang, R. Cooper, and M. Chang, J. Agric. Food Chem., 48, 5220 (2000).
Y. C. Su, J. J. Wang, T. T. Lin, and T. M. Pan, J. Ind. Microbiol. Biotechnol., 30, 40 (2003).
H. C. Wong and P. E. Koehler, J. Food Sci., 46, 589 (1981).
Y. Aniya, I. I. Ohtani, T. Higa, C. Miyagi, H. Gibo, M. Shimabukuro, H. Nakanish, and J. Taira, Free Radic. Biol. Med., 286, 999 (1999).
G. F. Wu and X. C. Wu, Acta Microbiol. Sin., 40, 394 (2000).
P. J. Blanc, M. O. Loret, and G. Goma, Biotechnol. Lett., 17, 291 (1995).
Ming-Der Wu, Ming-Jen Cheng, Tai-Wei Liu, Yen-Lin Chen, Hing-Yuen Chan, Hui-** Chen, Wen-Jung Wu, Kai-** Chen, and Gwo-Fang Yuan, Chem. Nat. Compd., 51, 554 (2015).
K. Tsuji, T. Ichikawa, N. Tanabe, S. Abe, S. Tarui, and Y. Nakagawa, Nippon. Nogeikagaku Kaishi., 66, 1241 (1992).
A. Endo, J. Med. Chem., 28, 401 (1985).
T. Akihisa, H. Tokuda, K. Yasukawa, M. Ukiya, A. Kiyota, N. Sakamoto, T. Suzuki, N. Tanabe, and H. Nishino, J. Agric. Food Chem., 53, 562 (2005).
M. J. Cheng, M. D. Wu, I. S. Chen, and G. F. Yuan, Chem. Pharm. Bull., 56, 394 (2008).
S. Jongrungruangchok, P. Kittakoop, B. Yongsmith, R. Bavovada, S. Tanasupawat, N. Lartpornmatulee, and Y. Thebtaranonth, Phytochemistry, 65, 2569 (2004).
Z. Huang, Y. Xu, L. Li, and Y. Li, J. Agric. Food Chem., 56, 112 (2008).
P. Juzlova, T. Rezanka, L. Martinkova, and V. Kren, Phytochemistry, 43, 151 (1996).
L. L. Li, J. P. Chen, and L. Y. Kong, Chin. J. Nat. Med., 4, 32 (2006).
D. Wild, G. Toth, and H. U. Humpf, J. Agric. Food Chem., 51, 5493 (2003).
K. Sato, Y. Goda, S. S. Sakamoto, H. Shibata, T. Maitani, and T. Yamada, Chem. Pharm. Bull., 45, 227 (1997).
M. O. Loret and S. Morel, J. Agric. Food Chem., 58, 1800 (2010).
W. A. Ayer and S. Miao, Can. J. Chem., 71, 487 (1993).
Acknowledgment
This investigation was supported by a grant from the Ministry of Economic Affairs of the Republic of China.
Author information
Authors and Affiliations
Corresponding authors
Additional information
Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2017, pp. 39–41.
Rights and permissions
About this article
Cite this article
Cheng, MJ., Wu, MD., Chan, HY. et al. New Metabolite Isolated from the Fungus Monascus pilosus . Chem Nat Compd 53, 44–47 (2017). https://doi.org/10.1007/s10600-017-1907-5
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-017-1907-5