Exposure of male Wistar rats to oxygen atmosphere at moderate pressure (1.10-1.15 atm) for 4 h resulted in significant, transient, and reversible decrease in hemolytic resistance of peripheral blood erythrocytes. In 2 days after oxygen exposure, the bone marrow released young erythrocytes with enhanced hemolytic resistance as a compensation for oxygen injury. These findings suggest that normobaric oxygen load can be viewed as a stress factor of moderate intensity.
Similar content being viewed by others
References
Azhikova AK, Zhuravleva GF. Research of hematologic indicators of rats is normal and in the conditions of thermal influence. Sovremen. Problemy Nauki Obrazovaniya. 2016;(2):284-292. Russian.
Borovskaya MK, Kuznetsov EE, Gorokhova VG, Koriakina LB, Kurilskaya TE, Pivovarov JuI. Structural and functional characteristics of membrane’s erythrocyte and its change at pathologies of various genesis. Byull. Vost.-Sib. Nauch. Tsentra Sib. Otdel. Ross. Akad. Med. Nauk. 2010;(3):334-354. Russian.
Vakhrushev YaM, Shkatova EYu. Laboratory Diagnostic Methods. Rostov-on-Don, 2007. Russian.
Izmest’eva OS, Luzyanina AA, Ershova IL, Zhavoronkov LP. Study of the effect of low-dose gamma irradiation on the functional state of peripheral blood erythrocytes in rats. Radiats. Biol. Radioekol. 2014;54(5):493-499. Russian.
Kamilov RF, Shakirova ED, Koudriavtsev VP, Shakirov DF. Acid and osmotic resistance of RBC in workers engaged into rubber and technical rubber production in petrochemical industry. Med. Truda Prom Ekol. 2008;(9):41-44. Russian.
Kozak MV. Age-related changes in erythrocyte osmotic resistance. Vestn. Nizhegorod. Univer. im. N. I. Lobachevskogo. 2010;(2-2):648-652. Russian.
Luniova SN, Yerofeyeva TN, Stogov MV, Romanenko SA, Nikolaichouck EV. Lipid peroxidation in treatment of closed shaft fractures using hyperbaric oxygenation. Genii Ortopedii. 2004;(4):37-40. Russian.
Minnulin IP, Logunov KV, Kuleshov VI, Artemov SL, Artemova YuI. Organization and features of hyperbaric oxygenation at the inpatient stage of emergency medical care. Skoraya Med. Pomoshch. 2014;15(3):32-40. Russian.
Roitman EV, Demet’eva II, Azizova OA, Nikitina NA, Gageva EV, Lopukhin YuM. Changes in the rheological properties of the blood and osmotic resistance of erythrocytes during activation of free-radical processes. Klin. Lab. Diagnost. 2001;(3):42-49. Russian.
Manual on Hyperbaric Medicine. Baidon SA, Gramenitskii AB, Rubinchik BA, eds. Moscow, 2008. Russian.
Ryabchenko NI, Dzikovskaya LA, Izmest’eva OS, Zhavoronkov LP. Effects of Exposure of Animals to Oxygen Atmosphere at Low Pressure on Lipid Peroxidation and Antioxidant Defense. Bull. Exp. Biol. Med. 2018;165(5):640-643. doi: https://doi.org/10.1007/s10517-018-4231-6
Trikulenko AV, Pinishko UV. Kinetics of acid lysis of erythrocytes of different age populations in the presence of ligands of some integral proteins of plasma membranes. Gematol. Transfuziol. 1999;44(1):16-18. Russian.
del Portillo I, Vázquez S, Mendoza J, Moreno R. Oxygen Therapy in Critical Care: A Double Edged Sword. Health. 2014;6(15):2035-2046. doi: https://doi.org/10.4236/health.2014.615238
Kallet RH, Matthay MA. Hyperoxic acute lung injury. Respir. Care. 2013;58(1):123-141. doi: https://doi.org/10.4187/respcare.01963
Revin VV, Gromova NV, Revina ES, Grunyushkin IP, Tuchkov AY, Samonova AY, Kukina AN, Moskovkin AA, Bourdon JC, Zhelev N. The effect of experimental hyperoxia on erythrocytes’ oxygen-transport function. Biotechnol. Biotechnol. Equipment. 2018;32(5):1236-1250. doi: https://doi.org/10.1080/13102818.2017.1414633
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 169, No. 2, pp. 156-160, February, 2020
Rights and permissions
About this article
Cite this article
Izmest’eva, O.S., Dzikovskaya, L.A. & Zhavoronkov, L.P. Effect of Rat Exposure to Moderate Pressure Oxygen Atmosphere on Resistance of Erythrocytes against Hemolysis. Bull Exp Biol Med 169, 201–204 (2020). https://doi.org/10.1007/s10517-020-04850-5
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-020-04850-5