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Laparoscopic versus open distal pancreatectomy for benign and low-grade malignant lesions of the pancreas: a single-center comparative study

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Abstract

Purpose

The purpose of the study was to compare the outcomes of laparoscopic distal pancreatectomy (LDP) and open distal pancreatectomy (ODP) for benign and low-grade malignant lesions to determine the safety and efficacy of LDP.

Methods

This retrospective comparative study included 67 consecutive patients who underwent LDP (n = 32) and ODP (n = 35) for benign or low-grade malignant lesions of the pancreas from January 2012 to March 2017. Thirty-five patients who were eligible for LDP in the ODP group were carefully selected. The clinical outcomes were compared in an intention-to-treat analysis.

Results

LDP was associated with significantly less operative blood loss (182 ± 232 vs. 505 ± 376 ml, P < 0.001) but a longer operation time (327 ± 89 vs. 173 ± 48 min, P < 0.001), than ODP. There were no significant differences between the 2 groups in the overall morbidity rates defined by Clavien–Dindo classification ≥ grade II (13% vs. 11%), clinically relevant postoperative pancreatic fistula rates (6% vs. 9%), and lengths of postoperative hospital stay (11 vs. 11 days).

Conclusion

The study showed that LDP was safe and feasible. LDP should be considered as the first-line treatment for benign and low-grade malignant lesions in the left side of the pancreas.

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Acknowledgements

No grant support was provided for this study.

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Authors and Affiliations

  1. Department of Surgery, Kindai University Faculty of Medicine, 377-2 Ohno-higashi, Osakasayama, Osaka, 589-8511, Japan

    Ippei Matsumoto, Keiko Kamei, Shumpei Satoi, Takaaki Murase, Masataka Matsumoto, Kohei Kawaguchi, Yuta Yoshida, Toshimitsu Iwasaki, Atsushi Takebe, Takuya Nakai & Yoshifumi Takeyama

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  1. Ippei Matsumoto
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  2. Keiko Kamei
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  3. Shumpei Satoi
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  4. Takaaki Murase
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  5. Masataka Matsumoto
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  6. Kohei Kawaguchi
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  7. Yuta Yoshida
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  11. Yoshifumi Takeyama
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Correspondence to Ippei Matsumoto.

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Cite this article

Matsumoto, I., Kamei, K., Satoi, S. et al. Laparoscopic versus open distal pancreatectomy for benign and low-grade malignant lesions of the pancreas: a single-center comparative study. Surg Today 49, 394–400 (2019). https://doi.org/10.1007/s00595-018-1743-7

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  • DOI: https://doi.org/10.1007/s00595-018-1743-7

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