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Comparison of acquisition rate and agreement of axial length with two swept-source optical coherence tomographers and a partial coherence interferometer

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Abstract

Purpose

To assess the acquisition rate and agreement of axial length (AL) measurements with the OA-2000, Anterion, and IOLMaster 500 in cataractous patients.

Methods

In total, 298 eyes of 191 cataractous patients were enrolled and scanned with the three devices in random order. The success rate of AL measurements per device was calculated and a chi-square test was utilized to identify the differences in acquisition rate between the three devices. Logistic regression analysis was applied to evaluate the association of different cataract types and severity with the AL measurement acquisition rate. Bland–Altman plots were mapped to appraise the agreement of AL values.

Results

AL measurements were successfully achieved in 288 eyes (96.64%) with the OA-2000, in 282 eyes (94.30%) with the Anteiron, and in 246 eyes (82.55%) with the IOLMaster 500. Significant differences in the acquisition rate were found between either of the SS-OCT devices and IOLMaster 500 by chi-square analysis (P < 0.001). No significant difference was noted between OA-2000 and Anterion. Increasing severity of posterior subcapsular cataract was associated with a higher failure rate with the IOLMaster 500. Bland–Altman analysis identified good agreement between the three biometers with narrow 95% limits of agreement.

Conclusions

The OA-2000 and Anterion showed similarly higher acquisition rate of AL measurements than IOLMaster 500 in cataractous patients. Good agreement for AL values was found between the three biometers in cataractous patients.

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Funding

This study was funded by the Wenzhou Key Team of Scientific and Technological Innovation (grant number C20170002), Wenzhou Public Welfare Science and Technology Projects (grant number Y20170192), Young Talents Programme of Zhejiang Medical and Health Science and Technology Project (grant number 2019RC223), Engineering Development Project of Ophthalmology and Optometry (grant number GCKF201601), Nature and Science Foundation of China (grant number 81570869), and Zhejiang Provincial Foundation of China for Distinguished Young Talents in Medicine and Health (grant number 2010QNA018). The funding organization had no role in the design or conduct of this research.

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Correspondence to A-Yong Yu.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the Ethics Committee of the Eye Hospital of Wenzhou Medical University and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Cheng, SM., Yan, Wt., Zhang, JS. et al. Comparison of acquisition rate and agreement of axial length with two swept-source optical coherence tomographers and a partial coherence interferometer. Graefes Arch Clin Exp Ophthalmol 260, 2905–2911 (2022). https://doi.org/10.1007/s00417-022-05681-y

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