Abstract
This study aimed to evaluate hydrogel properties produced by electrospraying alginate/AHSG (Alyssum homolocarpum seed gum) dispersions at different mixing ratios (0:100, 25:75, 50:50, 75:25, and 100:0). The results revealed that the ζ-potential and electrical conductivity of dispersions decreased with increasing the alginate to AHSG ratio. The dispersions were able to be atomized from the tip of the nozzle without the need for surfactant addition. The apparent viscosity increased with increasing alginate to AHSG ratio. The size of particles decreased, and their sphericity increased when the alginate to AHSG ratio increased. Intermolecular hydrogen bonds were formed between alginate and AHSG. The thermal stability of hydrogel increased as the alginate to AHSG ratio increased. At a mixing ratio of 75 alginate:25 AHSG, the porous structure of alginate hydrogel beads reduced. The XRD spectrum indicated that the crystalline structure of gums transformed into the amorphous state after the electrospraying.
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References
Abruzzo A, Bigucci F, Cerchiara T, Saladini B, Gallucci MC, Cruciani F, Luppi B (2013) Chitosan/alginate complexes for vaginal delivery of chlorhexidine digluconate. Carbohyd Polym 91(2):651–658. https://doi.org/10.1016/j.carbpol.2012.08.074
Alborzi S, Lim LT, Kakuda Y (2010) Electrospinning of sodium alginate-pectin ultrafine fibers. J Food Sci 75(1):C100–C107. https://doi.org/10.1111/j.1750-3841.2009.01437.x
Balanč B, Kalušević A, Drvenica I, Coelho MT, Djordjević V, Alves VD, Bugarski B (2016) Calcium–alginate–inulin microbeads as carriers for aqueous carqueja extract. J Food Sci 81(1):E65–E75. https://doi.org/10.1111/1750-3841.13167
Belščak-Cvitanović A, Komes D, Karlović S, Djaković S, Špoljarić I, Mršić G, Ježek D (2015) Improving the controlled delivery formulations of caffeine in alginate hydrogel beads combined with pectin, carrageenan, chitosan and psyllium. Food Chem 167:378–386. https://doi.org/10.1016/j.foodchem.2014.07.011
Bhattarai RS, Bachu RD, Boddu SH, Bhaduri S (2019) Biomedical applications of electrospun nanofibers: drug and nanoparticle delivery. Pharmaceutics 11(1):5. https://doi.org/10.3390/pharmaceutics11010005
Binsi PK, Nayak N, Sarkar PC, Jeyakumari A, Ashraf PM, Ninan G, Ravishankar CN (2017) Structural and oxidative stabilization of spray dried fish oil microencapsulates with gum Arabic and sage polyphenols: characterization and release kinetics. Food Chem 219:158–168. https://doi.org/10.1016/j.foodchem.2016.09.126
Bock N, Dargaville TR, Woodruff MA (2012) Electrospraying of polymers with therapeutic molecules: state of the art. Prog Polym Sci 37(11):1510–1551. https://doi.org/10.1016/j.progpolymsci.2012.03.002
Bonino CA, Krebs MD, Saquing CD, Jeong SI, Shearer KL, Alsberg E, Khan SA (2011) Electrospinning alginate-based nanofibers: from blends to crosslinked low molecular weight alginate-only systems. Carbohyd Polym 85(1):111–119. https://doi.org/10.1016/j.carbpol.2011.02.002
Borgogna M, Bellich B, Cesàro A (2011) Marine polysaccharides in microencapsulation and application to aquaculture:“from sea to sea.” Mar Drugs 9(12):2572–2604. https://doi.org/10.3390/md9122572
Bourbon AI, Pinheiro AC, Ribeiro C, Miranda C, Maia JM, Teixeira JA, Vicente AA (2010) Characterization of galactomannans extracted from seeds of Gleditsia triacanthos and Sophora japonica through shear and extensional rheology: comparison with guar gum and locust bean gum. Food Hydrocolloids 24(2–3):184–192. https://doi.org/10.1016/j.foodhyd.2009.09.004
Brunchi CE, Bercea M, Morariu S, Dascalu M (2016) Some properties of xanthan gum in aqueous solutions: effect of temperature and pH. J Polym Res 23(7):1–8. https://doi.org/10.1007/s10965-016-1015-4
Castillo-Orozco E, Kar A, Kumar R (2017) Electrospray mode transition of microdroplets with semiconductor nanoparticle suspension. Sci Rep 7(1):1–10. https://doi.org/10.1038/s41598-017-05175-6
Chan ES, Wong SL, Lee PP, Lee JS, Ti TB, Zhang Z, Yim ZH (2011) Effects of starch filler on the physical properties of lyophilized calcium–alginate beads and the viability of encapsulated cells. Carbohyd Polym 83(1):225–232. https://doi.org/10.1016/j.carbpol.2010.07.044
Coia KA, Stauffer KR (1987) Shelf life study of oil/water emulsions using various commercial hydrocolloids. J Food Sci 52(1):166–172. https://doi.org/10.1111/j.1365-2621.1987.tb13997.x
Córdoba AL, Deladino L, Martino M (2013) Effect of starch filler on calcium-alginate hydrogels loaded with yerba mate antioxidants. Carbohyd Polym 95(1):315–323. https://doi.org/10.1016/j.carbpol.2013.03.019
de Oliveira EF, Paula HC, de Paula RC (2014) Alginate/cashew gum nanoparticles for essential oil encapsulation. Colloids Surf B 113:146–51. https://doi.org/10.1016/j.colsurfb.2013.08.038
Dickinson, E., Galazka, V. B., & Anderson, D. M. (1991). Emulsifying behaviour of gum arabic. Part 2: effect of the gum molecular weight on the emulsion droplet-size distribution. Carbohydrate Polymers, 14(4), 385–392.https://doi.org/10.1016/0144-8617(91)90004-V
Fernández de La Mora J (2007) The fluid dynamics of Taylor cones. Annu Rev Fluid Mech 39:217–243
Flamminii F, Di Mattia CD, Nardella M, Chiarini M, Valbonetti L, Neri L, Pittia P (2020) Structuring alginate beads with different biopolymers for the development of functional ingredients loaded with olive leaves phenolic extract. Food Hydrocolloids 108:105849. https://doi.org/10.1016/j.foodhyd.2020.105849
Fundueanu G, Nastruzzi C, Carpov A, Desbrieres J, Rinaudo M (1999) Physico-chemical characterization of Ca-alginate microparticles produced with different methods. Biomaterials 20(15):1427–1435. https://doi.org/10.1016/S0142-9612(99)00050-2
George M, Abraham TE (2007) pH sensitive alginate–guar gum hydrogel for the controlled delivery of protein drugs. Int J Pharm 335(1–2):123–129. https://doi.org/10.1016/j.ijpharm.2006.11.009
Gómez-Estaca J, Balaguer MP, Gavara R, Hernandez-Munoz P (2012) Formation of zein nanoparticles by electrohydrodynamic atomization: Effect of the main processing variables and suitability for encapsulating the food coloring and active ingredient curcumin. Food Hydrocolloids 28(1):82–91. https://doi.org/10.1016/j.foodhyd.2011.11.013
Gómez-Mascaraque LG, Perez-Masiá R, González-Barrio R, Periago MJ, López-Rubio A (2017) Potential of microencapsulation through emulsion-electrospraying to improve the bioaccesibility of β-carotene. Food Hydrocolloids 73:1–12. https://doi.org/10.1016/j.foodhyd.2017.06.019
Han T, Yarin AL, Reneker DH (2008) Viscoelastic electrospun jets: initial stresses and elongational rheometry. Polymer 49(6):1651–1658. https://doi.org/10.1016/j.polymer.2008.01.035
Härdelin L, Thunberg J, Perzon E, Westman G, Walkenström P, Gatenholm P (2012) Electrospinning of cellulose nanofibers from ionic liquids: the effect of different cosolvents. J Appl Polym Sci 125(3):1901–1909. https://doi.org/10.1002/app.36323
Hayati I, Bailey AI, Tadros TF (1987) Investigations into the mechanisms of electrohydrodynamic spraying of liquids: I. Effect of electric field and the environment on pendant drops and factors affecting the formation of stable jets and atomization. J Colloid Interface Sci 117(1):205–221. https://doi.org/10.1016/0021-9797(87)90185-8
Jiang Z, Gan Y, Shi Y (2020) An improved model for prediction of the cone-jet formation in electrospray with the effect of space charge. J Aerosol Sci 139:105463. https://doi.org/10.1016/j.jaerosci.2019.105463
Khoshakhlagh K, Koocheki A, Mohebbi M, Allafchian A (2017) Development and characterization of electrosprayed Alyssum homolocarpum seed gum nanoparticles for encapsulation of d-limonene. J Colloid Interface Sci 490:562–575. https://doi.org/10.1016/j.jcis.2016.11.067
Koocheki A, Mortazavi SA, Shahidi F, Razavi SMA, Taherian AR (2009) Rheological properties of mucilage extracted from Alyssum homolocarpum seed as a new source of thickening agent. J Food Eng 91(3):490–496. https://doi.org/10.1016/j.jfoodeng.2008.09.028
Kowalewski TA, Błoński S, Barral S (2005) Experiments and modelling of electrospinning process. Bulletin of the polish academy of sciences: Technical sciences 385-394.https://doi.org/10.1016/S0021-8502(02)00088-5
Kumar P, Kapur PC, Saraf DN (1975) Effect of zeta potential on apparent viscosity of settling suspensions. Colloid Polym Sci 253(9):738–743. https://doi.org/10.1007/BF02464457
Kusuktham B, Prasertgul J, Srinun P (2014) Morphology and property of calcium silicate encapsulated with alginate beads. SILICON 6(3):191–197. https://doi.org/10.1007/s12633-013-9173-z
Larimi SG, Darzi HH, Darzi GN (2012) Fabrication and characterization of polyaniline/xanthan gum nanocomposite: Conductivity and thermal properties. Synth Met 162(1–2):171–5. https://doi.org/10.1016/j.synthmet.2011.11.027
Larosa C, Salerno M, de Lima JS, Meri RM, da Silva MF, de Carvalho LB, Converti A (2018) Characterisation of bare and tannase-loaded calcium alginate beads by microscopic, thermogravimetric, FTIR and XRD analyses. Int J Biol Macromol 115:900–906. https://doi.org/10.1016/j.ijbiomac.2018.04.138
Leyva-Porras C, Cruz-Alcantar P, Espinosa-Solís V, Martínez-Guerra E, Piñón-Balderrama CI, Compean Martínez I, Saavedra-Leos MZ (2020) Application of differential scanning calorimetry (DSC) and modulated differential scanning calorimetry (MDSC) in food and drug industries. Polymers 12(1):5. https://doi.org/10.3390/polym12010005
Loureiro dos Santos, L. A. Natural polymeric biomaterials: processing and properties. Reference Module in Materials Science and Materials Engineering. (2017)1–6.
Maiti S, Kumari L (2016) Smart nanopolysaccharides for the delivery of bioactives. In: Holban AM, Grumezescu A (ed) Nanoarchitectonics for Smart Delivery and Drug Targeting. USA, William Andrew Publishers, Inc., pp 67–92
Marcotte M, Piette JPG, Ramaswamy HS (1998) Electrical conductivities of hydrocolloid solutions. J Food Process Eng 21(6):503–520. https://doi.org/10.1111/j.1745-4530.1998.tb00466.x
Matalanis A, Jones OG, McClements DJ (2011) Structured biopolymer-based delivery systems for encapsulation, protection, and release of lipophilic compounds. Food Hydrocolloids 25(8):1865–1880. https://doi.org/10.1016/j.foodhyd.2011.04.014
McClements DJ (2015) Food emulsions: principles, practices, and techniques. CRC press
Morales-Sánchez E, Reyes-Vega ML, Gaytán-Martínez M, Figueroa-Cárdenas JD, Velázquez G (2015) Relationship between electrical conductivity and water activity of starch-water composites. In Water Stress in Biological, Chemical, Pharmaceutical and Food Systems (pp. 527–531). Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2578-0_48
Moreira R, Chenlo F, Silva C, Torres MD, Díaz-Varela D, Hilliou L, Argence H (2012) Surface tension and refractive index of guar and tragacanth gums aqueous dispersions at different polymer concentrations, polymer ratios and temperatures. Food Hydrocolloids 28(2):284–290. https://doi.org/10.1016/j.foodhyd.2012.01.007
Pawar SN, Edgar KJ (2012) Alginate derivatization: A review of chemistry, properties and applications. Biomaterials 33(11):3279–305. https://doi.org/10.1016/j.biomaterials.2012.01.007
Pérez-Masiá R, Lagaron JM, López-Rubio A (2014) Development and optimization of novel encapsulation structures of interest in functional foods through electrospraying. Food Bioprocess Technol 7(11):3236–3245. https://doi.org/10.1007/s11947-014-1304-z
Piras CC, Smith DK (2020) Multicomponent polysaccharide alginate-based bioinks. J Mater Chem B 8(36):8171–8188. https://doi.org/10.1039/D0TB01005G
Pongjanyakul T, Puttipipatkhachorn S (2007) Xanthan–alginate composite gel beads: molecular interaction and in vitro characterization. Int J Pharm 331(1):61–71. https://doi.org/10.1016/j.ijpharm.2006.09.011
Ramos PE, Silva P, Alario MM, Pastrana LM, Teixeira JA, Cerqueira MA, Vicente AA (2018) Effect of alginate molecular weight and M/G ratio in beads properties foreseeing the protection of probiotics. Food Hydrocolloids 77:8–16. https://doi.org/10.1016/j.foodhyd.2017.08.031
Rastogi R, Sultana Y, Aqil M, Ali A, Kumar S, Chuttani K, Mishra AK (2007) Alginate microspheres of isoniazid for oral sustained drug delivery. Int J Pharm 334(1–2):71–77. https://doi.org/10.1016/j.ijpharm.2006.10.024
Rezaeinia H, Ghorani B, Emadzadeh B, Tucker N (2019) Electrohydrodynamic atomization of Balangu (Lallemantia royleana) seed gum for the fast-release of Mentha longifolia L. essential oil: characterization of nano-capsules and modeling the kinetics of release. Food Hydrocolloids 93:374–385. https://doi.org/10.1016/j.foodhyd.2019.02.018
Rinaudo M (2008) Main properties and current applications of some polysaccharides as biomaterials. Polym Int 57(3):397–430. https://doi.org/10.1002/pi.2378
Santos C, Silva CJ, Büttel Z, Guimarães R, Pereira SB, Tamagnini P, Zille A (2014) Preparation and characterization of polysaccharides/PVA blend nanofibrous membranes by electrospinning method. Carbohydr Polym 99:584–92. https://doi.org/10.1016/j.carbpol.2013.09.008
Sarmento B, Ferreira D, Veiga F, Ribeiro A (2006) Characterization of insulin-loaded alginate nanoparticles produced by ionotropic pre-gelation through DSC and FTIR studies. Carbohyd Polym 66(1):1–7. https://doi.org/10.1016/j.carbpol.2006.02.008
Shekarforoush E, Faralli A, Ndoni S, Mendes AC, Chronakis IS (2017) Electrospinning of xanthan polysaccharide. Macromol Mater Eng 302(8):1700067. https://doi.org/10.1002/mame.201700067
Shewan HM, Stokes JR (2013) Review of techniques to manufacture micro-hydrogel particles for the food industry and their applications. J Food Eng 119(4):781–792. https://doi.org/10.1016/j.jfoodeng.2013.06.046
Smith DP (1986) The electrohydrodynamic atomization of liquids. IEEE Transactions on Industry Aupplications 3:527–535
Soares PA, Bourbon AI, Vicente AA, Andrade CA, Barros W Jr, Correia MT, Carneiro-da-Cunha MG (2014) Development and characterization of hydrogels based on natural polysaccharides: Policaju and chitosan. Mater Sci Eng, C 42:219–226. https://doi.org/10.1016/j.msec.2014.05.009
Steffe JF (1996) Rheological methods in food process engineering. Freeman press, pp 255
Stijnman AC, Bodnar I, Tromp RH (2011) Electrospinning of food-grade polysaccharides. Food Hydrocolloids 25(5):1393–1398. https://doi.org/10.1016/j.foodhyd.2011.01.005
Trotta M, Cavalli R, Trotta C, Bussano R, Costa L (2010) Electrospray technique for solid lipid-based particle production. Drug Dev Ind Pharm 36(4):431–438. https://doi.org/10.3109/03639040903241817
Vardhanabhuti B, Ikeda S (2006) Isolation and characterization of hydrocolloids from monoi (Cissampelos pareira) leaves. Food Hydrocolloids 20(6):885–891. https://doi.org/10.1016/j.foodhyd.2005.09.002
Wang B, Wan Y, Zheng Y, Lee X, Liu T, Yu Z, ... Gao B (2019) Alginate-based composites for environmental applications: a critical review. Crit Rev Environ Sci Technol 49(4):318–356.https://doi.org/10.1080/10643389.2018.1547621
Wu Y, Clark RL (2008) Electrohydrodynamic atomization: a versatile process for preparing materials for biomedical applications. J Biomater Sci Polym Ed 19(5):573–601. https://doi.org/10.1163/156856208784089616
Zhang S, Campagne C, Salaün F (2019) Influence of solvent selection in the electrospraying process of polycaprolactone. Appl Sci 9(3):402. https://doi.org/10.3390/app9030402
Zhang Z, Zhang R, Zou L, McClements DJ (2016) Protein encapsulation in alginate hydrogel beads: effect of pH on microgel stability, protein retention and protein release. Food Hydrocolloids 58:308–315. https://doi.org/10.1016/j.foodhyd.2016.03.015
Zong X, Kim K, Fang D, Ran S, Hsiao BS, Chu B (2002) Structure and process relationship of electrospun bioabsorbable nanofiber membranes. Polymer 43(16):4403–4412
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The authors greatly thank Ferdowsi University of Mashhad for financial and laboratory support (grant number: 3/48395).
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Mousavi, F., Koocheki, A., Ghorani, B. et al. Rheological properties, electrical conductivity, and surface activity of alginate/AHSG (Alyssum homolocarpum seed gum) blend and their effect on the formation of electrosprayed hydrogel beads. Rheol Acta 61, 649–661 (2022). https://doi.org/10.1007/s00397-022-01353-0
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DOI: https://doi.org/10.1007/s00397-022-01353-0