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Follow-Up of Secundum ASD, Muscular VSD, or PDA Diagnosed During Neonatal Hospitalization

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Abstract

The ideal follow-up of neonates who have a secundum atrial septal defect (ASD), muscular ventricular septal defect (VSD), or patent ductus arteriosus (PDA) remains uncertain. Newborns with findings limited to a secundum ASD, muscular VSD, and/or PDA on their neonatal hospitalization discharge echocardiogram and at least one outpatient follow-up echocardiogram performed between 9-1-17 and 9-1-21 were evaluated and patient follow-up assessed through 9-1-23. 95 infants met inclusion criteria. 43 infants had a secundum ASD, 41 had a muscular VSD, and 54 had a PDA at newborn hospital discharge. 39/95 had more than one intracardiac shunt. 56 were discharged from care, 26 were still in follow-up and 13 were lost to recommended follow-up. No patients received intervention during the follow-up period of 2 to 6 years. Of the 43 infants with a secundum ASD, 16 (37.2%) had demonstrated closure of the ASD, and 13 (30.2%) were discharged from care with an ASD < 3.5 mm in diameter. 3/43 infants with secundum ASD had a defect with a diameter of more than 5 mm at their last echocardiogram. No infant discharged from their neonatal hospitalization with a secundum ASD, muscular VSD, or PDA needed any intervention from 2 to 6 years of follow-up. Ongoing follow-up with echocardiography of those infants with a secundum ASD is of greater value than of those with muscular VSD or PDA.

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Data Availability

No datasets were generated or analysed during the current study.

Abbreviations

ASD:

Atrial septal defect

VSD:

Ventricular septal defect

PDA:

Patent ductus arteriosus

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Acknowledgements

This project was supported by the Clinical and Translational Science Award (CTSA) program, through the NIH National Center for Advancing Translational Sciences (NCATS), grant UL1TR002373. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Funding

No funding was sought to perform this study.

Author information

Authors and Affiliations

  1. Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC, USA

    Jacob Faultersack

  2. Transitional Year Intern, PGY-1, Intermountain Medical Center, Murry, UT, USA

    Christine M. Johnstad

  3. Division of Pediatric Cardiology, Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin, H6/516C, 600 Highland Ave., Madison, WI, 53792, USA

    **ao Zhang, Margaret Greco & John S. Hokanson

Authors
  1. Jacob Faultersack
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  2. Christine M. Johnstad
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  3. **ao Zhang
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  4. Margaret Greco
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  5. John S. Hokanson
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Contributions

All authors contributed to the study conception and design. Material preparation and data collection were performed by Jacob Faultersack, Christine Johnstad and John S. Hokanson. Statistical analysis was performed by **ao Zhang. Analysis of the final data was performed by all authors. The first draft of the manuscript was written by Jacob Faultersack and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to John S. Hokanson.

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Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (XLSX 10 KB)

Supplemental Table 1: Clinical Outcome Based on Indication for Initial Echocardiography

Supplementary file2 (XLSX 9 KB)

Supplemental Table 2: Patients Discharged from Care, In Ongoing Care and Lost to Follow-up

Supplementary file3 (XLSX 10 KB)

Supplemental Table 3: Follow-up Recommendations Based on Neonatal Hospital Discharge Diagnosis

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Faultersack, J., Johnstad, C.M., Zhang, X. et al. Follow-Up of Secundum ASD, Muscular VSD, or PDA Diagnosed During Neonatal Hospitalization. Pediatr Cardiol (2024). https://doi.org/10.1007/s00246-024-03537-2

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  • DOI: https://doi.org/10.1007/s00246-024-03537-2

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