Abstract
Purpose
Many surgeons are performing total knee arthroplasty (TKA) with an aim to reproducing native anatomical coronal alignment. Yet, it remains unclear if primary osteoarthritic and non-osteoarthritic populations have similar knee coronal alignment. This study aims to describe and compare the distribution of femoral and tibial coronal alignment in a large primary osteoarthritic cohort and a young non-osteoarthritic cohort.
Methods
This is a retrospective analysis of a monocentric prospectively gathered data, from 1990 to 2019, of 2859 consecutive primary osteoarthritic knees in 2279 patients. Patients underwent standardized long-leg radiographs. Femoral mechanical angle (FMA) and tibial mechanical angle (TMA) were digitally measured using software. Femoral, tibial and knee phenotypes were analyzed, and descriptive data were reported. Data were compared to a young non-osteoarthritic population previously described.
Results
In osteoarthritic knees, the mean FMA was 91° ± 2.9° (range 86°–100°) and the mean TMA was 87° ± 3.1° (range 80°–94°). No significant difference was observed for FMA and TMA between genders. The most common femoral and tibial phenotypes were varus (38.7%) and neutral (37.1%). The most frequent knee phenotype was a varus femoral phenotype with a neutral tibial phenotype (15.5%), which is different to the non-osteoarthritic population.
Conclusion
This study showed the wide distribution of knee phenotypes in a large osteoarthritic cohort. There was more varus distribution of the femoral coronal alignment compared to a non-osteoarthritic population, suggesting consideration and potential adaptation of the realignment strategy of the femoral component during TKA.
Level of evidence
III.
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References
Bellemans J, Colyn W, Vandenneucker H, Victor J (2012) The Chitranjan Ranawat award: is neutral mechanical alignment normal for all patients? The concept of constitutional varus. Clin Orthop Relat Res 470:45–53
Berend ME, Ritter MA, Meding JB, Faris PM, Keating EM, Redelman R, Faris GW, Davis KE (2004) Tibial component failure mechanisms in total knee arthroplasty. Clin Orthop Relat Res 428:26–34
Boonen B, Kerens B, Schotanus MGM, Emans P, Jong B, Kort NP (2016) Inter-observer reliability of measurements performed on digital long-leg standing radiographs and assessment of validity compared to 3D CT-scan. Knee 23:20–24
Brouwer RW, Jakma TSC, Brouwer KH, Verhaar JN (2007) Pitfalls in determining knee alignment: a radiographic cadaver study. J Knee Surg 20:210–215
Collins M, Lavigne M, Girard J, Vendittoli P-A (2012) Joint perception after hip or knee replacement surgery. Orthop Traumatol Surg Res 98:275–280
Cooke D, Scudamore A, Li J, Wyss U, Bryant T, Costigan P (1997) Axial lower-limb alignment: comparison of knee geometry in normal volunteers and osteoarthritis patients. Osteoarthr Cartil 5:39–47
Gbejuade HO, White P, Hassaballa M, Porteous AJ, Robinson JR, Murray JR (2014) Do long leg supine CT scanograms correlate with weight-bearing full-length radiographs to measure lower limb coronal alignment? Knee 21:549–552
Hess S, Moser LB, Amsler F, Behrend H, Hirschmann MT (2019) Highly variable coronal tibial and femoral alignment in osteoarthritic knees: a systematic review. Knee Surg Sports Traumatol Arthrosc 27:1368–1377
Hirschmann MT, Hess S, Behrend H, Amsler F, Leclercq V, Moser LB (2019) Phenoty** of hip-knee-ankle angle in young non-osteoarthritic knees provides better understanding of native alignment variability. Knee Surg Sports Traumatol Arthrosc 27:1378–1384
Hirschmann MT, Konala P, Amsler F, Iranpour F, Friederich NF, Cobb JP (2011) The position and orientation of total knee replacement components: a comparison of conventional radiographs, transverse 2D-CT slices and 3D-CT reconstruction. J Bone Jt Surg Br 93:629–633
Hirschmann MT, Moser LB, Amsler F, Behrend H, Leclercq V, Hess S (2019) Phenoty** the knee in young non-osteoarthritic knees shows a wide distribution of femoral and tibial coronal alignment. Knee Surg Sports Traumatol Arthrosc 27:1385–1393
Hirschmann MT, Moser LB, Amsler F, Behrend H, Leclerq V, Hess S (2019) Functional knee phenotypes: a novel classification for phenoty** the coronal lower limb alignment based on the native alignment in young non-osteoarthritic patients. Knee Surg Sports Traumatol Arthrosc 27:1394–1402
Jabalameli M, Moghimi J, Yeganeh A, Nojomi M (2015) Parameters of lower extremities alignment view in Iranian adult population. Acta Med Iran 53:293–296
Lazennec JY, Chometon Q, Folinais D, Robbins CB, Pour AE (2017) Are advanced three-dimensional imaging studies always needed to measure the coronal knee alignment of the lower extremity? Int Orthop 41:917–924
Longstaff LM, Sloan K, Stamp N, Scaddan M, Beaver R (2009) Good alignment after total knee arthroplasty leads to faster rehabilitation and better function. J Arthroplasty 24:570–578
Lonner JH, Laird MT, Stuchin SA (1996) Effect of rotation and knee flexion on radiographic alignment in total knee arthroplasties. Clin Orthop Relat Res 331:102–106
Magnussen RA, Weppe F, Demey G, Servien E, Lustig S (2011) Residual varus alignment does not compromise results of TKAs in patients with preoperative varus. Clin Orthop Relat Res 469:3443–3450
Nam D, Nunley RM, Barrack RL (2014) Patient dissatisfaction following total knee replacement: a growing concern? Bone Jt J 96-B:96–100
Oussedik S, Abdel MP, Victor J, Pagnano MW, Haddad FS (2020) Alignment in total knee arthroplasty. Bone Jt J 102B:276–279
Paley D, Tetsworth K (1992) Mechanical axis deviation of the lower limbs. Preoperative planning of uniapical angular deformities of the tibia or femur. Clin Orthop Relat Res 280:48–64
Parratte S, Pagnano MW, Trousdale RT, Berry DJ (2010) Effect of postoperative mechanical axis alignment on the 15-year survival of modern, cemented total knee replacements. J Bone Jt Surg Am 92:2143–2149
Ritter MA, Faris PM, Keating EM, Meding JB (1994) Postoperative alignment of total knee replacement. Its effect on survival. Clin Orthop Relat Res 299:153–156
Rivière C, Iranpour F, Auvinet E, Aframian A, Asare K, Harris S, Cobb J, Parratte S (2017) Mechanical alignment technique for TKA: are there intrinsic technical limitations? Orthop Traumatol Surg Res 103:1057–1067
Rivière C, Iranpour F, Auvinet E, Howell S, Vendittoli P-A, Cobb J, Parratte S (2017) Alignment options for total knee arthroplasty: a systematic review. Orthop Traumatol Surg Res 103:1047–1056
Rivière C, Lazic S, Boughton O, Wiart Y, Vïllet L, Cobb J (2018) Current concepts for aligning knee implants: patient-specific or systematic? EFORT Open Rev 3:1–6
Slevin O, Amsler F, Hirschmann MT (2017) No correlation between coronal alignment of total knee arthroplasty and clinical outcomes: a prospective clinical study using 3D-CT. Knee Surg Sports Traumatol Arthrosc 25:3892–3900
Sorin G, Pasquier G, Drumez E, Arnould A, Migaud H, Putman S (2016) Reproducibility of digital measurements of lower-limb deformity on plain radiographs and agreement with CT measurements. Orthop Traumatol Surg Res 102:423–428
Tew M, Waugh W (1985) Tibiofemoral alignment and the results of knee replacement. J Bone Jt Surg Br 67:551–556
Victor J, Van Doninck D, Labey L, Van Glabbeek F, Parizel P, Bellemans J (2009) A common reference frame for describing rotation of the distal femur: a CT-based kinematic study using cadavers. J Bone Jt Surg Br 91:683–690
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Prof. Sébastien Lustig has performed consultancy work for Medacta, Heraeus, Corin, Amplitude, Groupe Lépine, Depuy Synthes, Smith&Nephew, Stryker. Prof. Sébastien Lustig receives institutional research support from Corin and Amplitude. Prof. Sébastien Lustig is a board member of KSSTA and Maitrise Orthopédique. The other authors declare that they have no conflicts of interest.
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The French advisory committee on health research data processing (Comité Consultatif sur le Traitement de l’Information en matière de Recherche dans le domaine de la Santé [CCTIRS]) approved this study on the 24th January 2012 and then 9 March 2015 (approval #11681).
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Sappey-Marinier, E., Batailler, C., Swan, J. et al. Primary osteoarthritic knees have more varus coronal alignment of the femur compared to young non-arthritic knees in a large cohort study. Knee Surg Sports Traumatol Arthrosc 30, 428–436 (2022). https://doi.org/10.1007/s00167-020-06083-5
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DOI: https://doi.org/10.1007/s00167-020-06083-5