Anatomy of Portal Vein System

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Portal Vein Thrombosis

Abstract

The abdomen is unique to have two venous systems—the systemic and portal system. The systemic venous network drains directly into the inferior vena cava, whereas the portal system delivers the blood to the liver via the hepatic portal vein. The portal venous blood gets filtered through the hepatic sinusoids to enter the hepatic veins and finally the inferior vena cava. The mesenteric and splenic veins are its main tributaries but smaller veins from the stomach, pancreas, and gallbladder also contribute to this system. The portal venous system is subject to various congenital and acquired disorders, most importantly portal venous obstruction/thrombosis and portal hypertension. Proper understanding of the anatomy of the portal venous system is imperative for the diagnosis, management, and effective treatment planning of these disorders. Variant anatomy and congenital anomalies of the portal venous system are particularly important to identify in the context of consideration of liver transplantation or hepatic resections and interventional procedures like transjugular intrahepatic portosystemic shunt, portal vein embolization, etc. In this chapter, we will review the embryology and anatomy of the portal venous system, discuss its complex tributaries, and also succinctly learn about relevant anatomical and topographical variants in light of their significance prior to surgical or interventional treatments.

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References

  1. Carneiro C, Brito J, Bilreiro C, et al. All about portal vein: a pictorial display to anatomy, variants and physiopathology. Insights Imaging. 2019;10:38.

    Article  Google Scholar 

  2. Collardeau-Frachon S, Scoazec JY. Vascular development and differentiation during human liver organogenesis. Anat Rec (Hoboken). 2008;291(6):614–27. https://doi.org/10.1002/ar.20679.

    Article  Google Scholar 

  3. Marks C. Developmental basis of the portal venous system. Am J Surg. 1969;117(5):671–81.

    Article  CAS  Google Scholar 

  4. Sharma M, Babu CS, Garg S, Rai P. Portal venous system and its tributaries: a radial endosonographic assessment. Endosc Ultrasound. 2012;1(2):96–107. https://doi.org/10.7178/eus.02.008.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Rameshbabu CS, Wani ZA, Rai P, Abdulqader A, Garg S, Sharma M. Standard imaging techniques for assessment of portal venous system and its tributaries by linear endoscopic ultrasound: a pictorial essay. Endosc Ultrasound. 2013;2(1):16–34. https://doi.org/10.7178/eus.04.005.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Sharma M, Rameshbabu CS. Collateral pathways in portal hypertension. J Clin Exp Hepatol. 2012;2(4):338–52. https://doi.org/10.1016/j.jceh.2012.08.001.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Rajesh S, Mukund A, Arora A. Imaging diagnosis of splanchnic venous thrombosis. Gastroenterol Res Pract. 2015;2015:101029. https://doi.org/10.1155/2015/101029.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Philips CA, Arora A, Shetty R, Kasana V. A comprehensive review of portosystemic collaterals in cirrhosis: historical aspects, anatomy, and classifications. Int J Hepatol. 2016;2016:6170243. https://doi.org/10.1155/2016/6170243.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Bandali MF, et al. Portal hypertension: imaging of portosystemic collateral pathways and associated image-guided therapy. World J Gastroenterol. 2017;23(10):1735–46. https://doi.org/10.3748/wjg.v23.i10.1735.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Arora A, Rajesh S, Meenakshi YS, Sureka B, Bansal K, Sarin SK. Spectrum of hepatofugal collateral pathways in portal hypertension: an illustrated radiological review. Insights Imaging. 2015;6(5):559–72. https://doi.org/10.1007/s13244-015-0419-8.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Abby Philips C, Sahney A. Oesophageal and gastric varices: historical aspects, classification and grading: everything in one place. Gastroenterol Rep (Oxf). 2016;4(3):186–95. https://doi.org/10.1093/gastro/gow018.

    Article  Google Scholar 

  12. Smith CS, Sheehy N, McEniff N, Keogan MT. Magnetic resonance portal venography: use of fast acquisition true FISP imaging in the detection of portal vein thrombosis. Clin Radiol. 2007;62(12):1180–8.

    Article  CAS  Google Scholar 

  13. Sureka B, Patidar Y, Bansal K, Rajesh S, Agrawal N, Arora A. Portal vein variations in 1000 patients: surgical and radiological importance. Br J Radiol. 2015;88:20150326.

    Article  Google Scholar 

  14. Guerra A, De Gaetano AM, Infante A, et al. Imaging assessment of portal venous system: pictorial essay of normal anatomy, anatomic variants and congenital anomalies. Eur Rev Med Pharmacol Sci. 2017;21(20):4477–86.

    CAS  PubMed  Google Scholar 

  15. Koc Z, Ulusan S, Oguzkurt L, Tokmak N. Venous variants and anomalies on routine abdominal multi-detector row CT. Eur J Radiol. 2007;61(2):267–78. https://doi.org/10.1016/j.ejrad.2006.09.008.

    Article  PubMed  Google Scholar 

  16. Koç Z, Oğuzkurt L, Ulusan S. Portal vein variations: clinical implications and frequencies in routine abdominal multidetector CT. Diagn Interv Radiol. 2007;13(2):75–80.

    PubMed  Google Scholar 

  17. Akgul E, Inal M, Soyupak S, Binokay F, Aksungur E, Oguz M. Portal venous variations. Prevalence with contrast-enhanced helical CT. Acta Radiol. 2002;43(3):315–9. https://doi.org/10.1080/j.1600-0455.2002.430314.x.

    Article  CAS  PubMed  Google Scholar 

  18. Schmidt S, Demartines N, Soler L, Schnyder P, Denys A. Portal vein normal anatomy and variants: implication for liver surgery and portal vein embolization. Semin Interv Radiol. 2008;25(2):86–91. https://doi.org/10.1055/s-2008-1076688.

    Article  Google Scholar 

  19. Nakamura TN, Tanaka K, Kiuchi T, et al. Anatomical variations and surgical strategies in right lobe living donor liver transplantation: lessons from 120 cases. Transplantation. 2002;73:1896–903.

    Article  Google Scholar 

  20. Iqbal S, Iqbal R, Iqbal F. Surgical implications of portal vein variations and liver segmentations: a recent update. J Clin Diagn Res. 2017;11(2):AE01–5. https://doi.org/10.7860/JCDR/2017/25028.9453.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Kamel IR, Kruskal JB, Pomfret EA, Keogan MT, Warmbrand G, Raptopoulos V. Impact of multidetector CT on donor selection and surgical planning before living adult right lobe liver transplantation. AJR. 2001;176:193–200.

    Article  CAS  Google Scholar 

  22. Covey AM, Brody LA, Getrajdman GI, Sofocleous CT, Brown KT. Incidence, patterns, and clinical relevance of variant portal vein anatomy. Am J Roentgenol. 2004;183:1055–64. https://doi.org/10.2214/ajr.183.4.1831055.

    Article  Google Scholar 

  23. Gunasekaran SS, Gaba RC. Anatomic variations of the right portal vein: prevalence, imaging features, and implications for successful transjugular intrahepatic portosystemic shunt creation. J Clin Imaging Sci. 2017;7:14.

    Article  Google Scholar 

  24. Saad N, Darcy M, Saad W. Portal anatomic variants relevant to transjugular intrahepatic portosystemic shunt. Tech Vasc Interv Radiol. 2008;11(4):203–7. https://doi.org/10.1053/j.tvir.2009.04.008.

    Article  PubMed  Google Scholar 

  25. Farsad K, Kaufman JA. Novel image guidance techniques for portal vein targeting during transjugular intrahepatic portosystemic shunt creation. Tech Vasc Interv Radiol. 2016;19(1):10–20. https://doi.org/10.1053/j.tvir.2016.01.002.

    Article  PubMed  Google Scholar 

  26. Zhuang ZW, Teng GJ, Jeffery RF, Gemery JM, Janne d’Othee B, Bettmann MA. Long-term results and quality of life in patients treated with transjugular intrahepatic portosystemic shunts. AJR Am J Roentgenol. 2002;179(6):1597–603.

    Article  Google Scholar 

  27. Vignali C, Bargellini I, Grosso M, et al. TIPS with expanded polytetrafluoroethylene-covered stent: results of an Italian multicenter study. AJR Am J Roentgenol. 2005;185(2):472–80.

    Article  Google Scholar 

  28. Kanterman RY, Darcy MD, Middleton WD, Sterling KM, Teefey SA, Pilgram TK. Doppler sonography findings associated with transjugular intrahepatic portosystemic shunt malfunction. AJR Am J Roentgenol. 1997;168(2):467–72.

    Article  CAS  Google Scholar 

  29. Camelo R, Luz JH, Gomes FV, Coimbra E, Costa NV, Bilhim T. Portal vein embolization with PVA and coils before major hepatectomy: single-center retrospective analysis in sixty-four patients. J Oncol. 2019;2019:4634309. https://doi.org/10.1155/2019/4634309.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Anwar AS, Srikala J, Papalkar AS, Parveez MQ, Sharma A. Study of anatomical variations of hepatic vasculature using multidetector computed tomography angiography. Surg Radiol Anat. 2020;42:1449–57. https://doi.org/10.1007/s00276-020-02532-5.

    Article  PubMed  Google Scholar 

  31. Franchi-Abella S, Gonzales E, Ackermann O, et al. Congenital portosystemic shunts: diagnosis and treatment. Abdom Radiol (NY). 2018;43(8):2023–36. https://doi.org/10.1007/s00261-018-1619-8.

    Article  Google Scholar 

  32. DiPaola F, Trout AT, Walther AE, et al. Congenital portosystemic shunts in children: associations, complications, and outcomes. Dig Dis Sci. 2020;65(4):1239–51. https://doi.org/10.1007/s10620-019-05834-w.

    Article  PubMed  Google Scholar 

  33. Bernard O, Franchi-Abella S, Branchereau S, Pariente D, Gauthier F, Jacquemin E. Congenital portosystemic shunts in children: recognition, evaluation, and management. Semin Liver Dis. 2012;32(4):273–87. https://doi.org/10.1055/s-0032-1329896.

    Article  CAS  PubMed  Google Scholar 

  34. Stringer MD. The clinical anatomy of congenital portosystemic venous shunts. Clin Anat. 2008;21(2):147–57.

    Article  Google Scholar 

  35. Howard ER, Davenport M. Congenital extrahepatic portocaval shunts—the Abernethy malformation. J Pediatr Surg. 1997;32(3):494–7. https://doi.org/10.1016/s0022-3468(97)90614-x.

    Article  CAS  PubMed  Google Scholar 

  36. Eduardo Alonso-Gamarra, Manuel ParrĂłn, Ana PĂ©rez, Consuelo Prieto, Loreto Hierro, Manuel LĂłpez-SantamarĂ­a Clinical and radiologic manifestations of congenital extrahepatic portosystemic shunts: a comprehensive review. Radiographics 2011: 31: 707

    Article  Google Scholar 

  37. Bhargava P, Vaidya S, Kolokythas O, Katz DS, Dighe M. Hepatic vascular shunts: embryology and imaging appearances. Br J Radiol. 2011;84:1142–52.

    Article  CAS  Google Scholar 

  38. Lupescu I, Masala N, Capsa R, Câmpeanu N, Georgescu SA. CT and MRI of acquired portal venous system anomalies. J Gastrointestin Liver Dis. 2006;15(4):393–8.

    PubMed  Google Scholar 

  39. Zhang DY, Weng SQ, Dong L, Shen XZ, Qu XD. Portal hypertension induced by congenital hepatic arterioportal fistula: report of four clinical cases and review of the literature. World J Gastroenterol. 2015;21(7):2229–35. https://doi.org/10.3748/wjg.v21.i7.2229.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Norton SP, Jacobson K, Moroz SP, et al. The congenital intrahepatic arterioportal fistula syndrome: elucidation and proposed classification. J Pediatr Gastroenterol Nutr. 2006;43(2):248–55. https://doi.org/10.1097/01.mpg.0000221890.13630.ad.

    Article  PubMed  Google Scholar 

  41. Gallego C, Velasco M, Pilar Marcuello P, Tejedor D, De Campo L, Friera A. Congenital and acquired anomalies of the portal venous system. Radiographics. 2002;22:141–59.

    Article  Google Scholar 

  42. Lopez-Machado E, Mallorquin-Jimenez F, Medina-Benitez A, Ruiz-Carazo E, Cubero-Garcia M. Aneurysms of the portal venous system: ultrasonography and CT findings. Eur J Radiol. 1998;26:210–4.

    Article  CAS  Google Scholar 

  43. Laurenzia A, Ettorrea GM, Lionettib R, Meniconia LR, Colasantia M, Vennareccia G. Portal vein aneurysm: what to know. Dig Liver Dis. 2015;47(11):918–23.

    Article  Google Scholar 

  44. Rusu S, Zaghal A, Choudhry MS. Surgical decision making in preduodenal portal vein: report of two cases in neonates. Eur J Pediatr Surg Rep. 2018;6(1):e40–2. https://doi.org/10.1055/s-0038-1661409.

    Article  Google Scholar 

  45. Kim SH, Cho YH, Kim HY. Preduodenal portal vein: a 3-case series demonstrating varied presentations in infants. J Korean Surg Soc. 2013;85(4):195–7. https://doi.org/10.4174/jkss.2013.85.4.195.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Arora A, Velayutham P, Rajesh S, Patidar Y, Mukund A, Bharathy KG. Circumportal pancreas: a clinicoradiological and embryological review. Surg Radiol Anat. 2014;36(4):311–9. https://doi.org/10.1007/s00276-013-1189-y.

    Article  PubMed  Google Scholar 

  47. Kabir T, Xuan ZTZ, Chung AYF. Circumportal pancreas: a report of two cases. Ann Hepatobil Pancreat Surg. 2019;23(3):300–4. https://doi.org/10.14701/ahbps.2019.23.3.300.

    Article  Google Scholar 

  48. Ohtsuka T, Mori Y, Ishigami K, Fujimoto T, Miyasaka Y, Nakata K, et al. Clinical significance of circumportal pancreas, a rare congenital anomaly, in pancreatectomy. Am J Surg. 2017;214:267–72.

    Article  Google Scholar 

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Das, R., Chambers, J., Arora, A. (2021). Anatomy of Portal Vein System. In: Qi, X., **e, W. (eds) Portal Vein Thrombosis. Springer, Singapore. https://doi.org/10.1007/978-981-33-6538-4_1

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  • DOI: https://doi.org/10.1007/978-981-33-6538-4_1

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