Leiomyosarcoma of the Inferior Vena Cava

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Tropical Cardiovascular Pathology
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Abstract

Only 2% of leiomyosarcomas have a vascular origin and over 50% of these tumors affect the inferior vena cava, which are predominantly present in women. The clinical presentation depends on the location of the tumor, patterns of growth, and degree of differentiation. Despite the sarcomatous nature, the tumors are often slowly growing with an insidious presentation and consequent delayed diagnosis. We report a very large caval tumor mimicking a thrombus in a young woman with luminal and extra-luminal growth and extension into the right atrium.

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Further Reading

  • Joung HS, Nooromid MJ, Eskandari MK, Wayne JD. Surgical approach, management, and oncologic outcomes of primary leiomyosarcoma of the inferior vena cava: an institutional case series. J Surg Oncol. 2020;122:1348–55.

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  • Nabati M, Azizi S. Leiomyosarcoma of the inferior vena cava presenting as a cardiac mass. J Clin Ultrasound. 2018;46:430–3.

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  • Rusu CB, Gorbatâi L, Szatmari L, Koren R, Bungărdean CI, Feciche BO, et al. Leiomyosarcoma of the inferior vena cava. Our experience and a review of the literature. Rom J Morphol Embryol. 2020;61:227–33.

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  • Suneetha KP, Gudaganatti SB, Gayathri J. Rare case presentation of leiomyosarcoma as IVC thrombus. Indian J Surg Oncol. 2019;10:540–1.

    Article  CAS  Google Scholar 

  • Wang MX, Menias CO, Elsherif SB, Segaran N, Ganeshan D. Current update on IVC leiomyosarcoma. Abdom Radiol (NY). 2021;46:5284–96.

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Vaideeswar, P. (2022). Leiomyosarcoma of the Inferior Vena Cava. In: Vaideeswar, P. (eds) Tropical Cardiovascular Pathology. Springer, Singapore. https://doi.org/10.1007/978-981-19-3720-0_56

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  • DOI: https://doi.org/10.1007/978-981-19-3720-0_56

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-3719-4

  • Online ISBN: 978-981-19-3720-0

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