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Oxidative Coupling Reactions Between Hydrocarbons and Organometallic Reagents (The Second Generation)

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Transition Metal Catalyzed Oxidative Cross-Coupling Reactions

Part of the book series: Lecture Notes in Chemistry ((LNC,volume 102))

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Abstract

The development of new methods which enable the functionalization of C–H bonds is an important challenge to the continued advance of chemical synthesis. In recent years, by viewing C–H bonds as “nucleophiles”, the merge of C–H functionalization with oxidative cross-coupling reactions opens a new chapter in organic synthesis with many exciting opportunities. This chapter summarizes the developments and advancements in the emerging area of oxidative coupling reactions between hydrocarbons and various organometallic reagents (the second-generation oxidative couplings). The structure of this chapter is organized by the hybridization of the C–H bonds, as well as the differences between organometallic reagents.

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  1. Department of Chemistry and Shenzhen Grubbs Institute, Southern University of Science and Technology, Shenzhen, Guangdong, China

    Chuan He

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  1. College of Chemistry & Molecular Sciences, Wuhan University, Wuhan, China

    Aiwen Lei

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He, C. (2019). Oxidative Coupling Reactions Between Hydrocarbons and Organometallic Reagents (The Second Generation). In: Lei, A. (eds) Transition Metal Catalyzed Oxidative Cross-Coupling Reactions. Lecture Notes in Chemistry, vol 102. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58104-9_3

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