Zusammenfassung

Bei der akuten Pankreatitis handelt es sich um eine potenziell tödlich verlaufende Erkrankung mit individuell unterschiedlich ausgeprägter systemischer Beteiligung. Aus diesem Grund kommen der frühzeitigen Diagnose und nachfolgenden Risikostratifikation im klinischen Management dieser häufigen gastroenterologischen Erkrankung entscheidende Rollen zu. Schwere Verlaufsformen treten in etwa 20% der Fälle auf und bedürfen zumeist intensivmedizinischer Überwachung und interdisziplinärer Behandlung. Therapeutisch stehen in der Akutphase die adäquate Flüssigkeitssubstitution und suffiziente Schmerztherapie im Vordergrund. Im Hinblick auf den Einsatz von Antibiotika und die Anpassung der Ernährung hat sich in den letzten Jahren ein Paradigmenwechsel vollzogen. Je nach Schwere der Erkrankung und möglichen Komplikationen können auch endoskopisch-/radiologisch-interventionelle Maßnahmen oder eine operative Versorgung notwendig werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

eBook
EUR 24.27
Price includes VAT (France)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

Literatur

  1. Tenner 5, Baillie J, DeWitt J, Vege 55 (2013) American College of Gastroenterology guideline: management of acute pancreatitis. Am JGastroenterol 108:1400-1415, 141–6

    Google Scholar 

  2. Banks PA, Freeman ML (2006) Practice guidelines in acute pancreatitis. Am JGastroenteroI101:2379–2400

    Google Scholar 

  3. Yadav D, Lowenfels AB (2006) Trends in the epidemiology of the first attack of acute pancreatitis: asystematic review. Pancreas 33:323–330

    PubMed  Google Scholar 

  4. Bittinger M, Messmann H (2011) Acute pancreatitis. Med Klin Intensivmed Notfmed 106:221–230

    PubMed  Google Scholar 

  5. Pandol SJ, Saluja AK, Imrie CW, Banks PA (2007) Acute pancreatitis: bench to the bedside. Gastroenterology 132:1127–1151

    Article  PubMed  Google Scholar 

  6. Banks PA, Bollen TL, Dervenis Cet al (2013) Classification of acute pancreatitis - 2012: revision of the Atlanta c1assification and definitions by international consensus. Gut 62:1 0211–1

    Article  Google Scholar 

  7. Runzi M, Layer P, BuchlerMW et al (2000) The therapy of acute pancreatitis. General guidelines. Working group of the Society for ScientificMedical Specialties. ZGastroenterol 38:571–581

    Google Scholar 

  8. Dervenis C, Johnson CD, Bassi Cet al (1999) Diagnosis, objective assessment of severity, and management of acute pancreatitis. Santorini consensus conference. Int JPancreatol 25:195–210

    Google Scholar 

  9. Brown A, Orav J, Banks PA (2000) Hemoconcentration is an early marker for organ failure and necrotizing pancreatitis. Pancreas 20:367–372

    Article  PubMed  Google Scholar 

  10. Hecker M, Weigand MA, Mayer K (2012) Acute respiratory distress syndrome. lnternist (Berl) 53:557–566

    Google Scholar 

  11. Huber W, Umgelter A, ReindlWet al (2008) Volume assessment in patients with necrotizing pancreatitis: a comparison of intrathoracic blood volume index, central venous pressure, and hematocrit, and their correlation to cardiac index and extravascular lung water index. Crit Care Med 36:2348–2354

    Google Scholar 

  12. Thompson DR (2001) Narcotic analgesic effects on the sphincter of Oddi: a review of the data and therapeutic implications in treating pancreatitis. Am JGastroenterol 96:1266–1272

    Google Scholar 

  13. Kahl 5, Zimmermann 5, Pross Met al (2004) Procaine hydrochloride fails to relieve pain in patients with acute pancreatitis. Digestion 69:5–9

    Google Scholar 

  14. Villatoro E, Mulla M, Larvin M (2010) Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis. Cochrane Database Syst Rev:CD002941

    Google Scholar 

  15. AI-Omran M, Albalawi ZH, Tashkandi MF, AI-Ansary LA (2010) Enteral versus parenteral nutrition for acute pancreatitis. Cochrane Database Syst Rev:CD002837

    Google Scholar 

  16. Eatock FC, Chong P, Menezes Net al (2005) A randomized study of earIy nasogastric versus nasojejunal feeding in severe acute pancreatitis. Am JGastroenteroI100:432–439

    Google Scholar 

  17. Hecker M, FelbingerT, Mayer K (2012) Nutrition in intensive care medicine. Anaesthesist 61 :553–564

    Article  PubMed  Google Scholar 

  18. Hecker M, FelbingerTW, Mayer K (2013) Nutrition in intensive care medicine: part 2: special nutritional problems. Anaesthesist 62:233–241

    PubMed  Google Scholar 

  19. Besselink MG, Santvoort HC van, Buskens Eet al (2008) Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, doubleblind, placebo-controlled trial. Lancet371 :651–659

    Google Scholar 

  20. Seifert H, Biermer M, SchmittWet al (2009) Transluminal endoscopic necrosectomy after acute pancreatitis: amuIticentre study with long-term follow-up (the GEPARD Study). Gut 58:1260–1266

    Google Scholar 

  21. Santvoort HC van, Besselink MG, Bakker OJ et al (2010) A step-up approach or open necrosectomyfor necrotizing pancreatitis. NEngl J Med 362:1491–1502

    Google Scholar 

  22. Santvoort HC van, Bakker OJ, Bollen TL et al (2011) Aconservative and minimally invasive approach to necrotizing pancreatitis improves outcome. Gastroenterology 141:1254126–3

    Google Scholar 

  23. Garg PK, Sharma M, Madan Ket al (2010) Primary conservative treatment results in mortality comparable to surgery in patients with infected pancreatic necrosis. C1in Gastroenterol Hepatol 8:1089-1 094.e2

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hecker, M. et al. (2015). Akute Pankreatitis. In: Weiterbildung Anästhesiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46515-8_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-46515-8_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-46514-1

  • Online ISBN: 978-3-662-46515-8

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Navigation