Abstract
More than 800,000 patients undergo coronary artery bypass grafting (CABG) each year worldwide (Nalysnyk et al. Heart 89:767–772, 2003). In the recent years, there have been major advances in techniques used in CABG surgery in order to assure better success rates and reduce complication rates. Thus, there has been a move toward arterial graft revascularization as compared to venous grafts in order to allow longer patency rates. In addition, newer methods such as minimal access and off cardiopulmonary bypass (CPB) surgery are now in routine practice in many centers around the world with an aim to reduce the rates of postoperative morbidity and length of hospital stay. Despite such advances, patients that present for CABG are older and increasingly frail with multiple cardiac and other comorbidities compared to those patients operated on in the last century. Hence, the risk of significant postoperative morbidity and mortality still exists and is even expected to increase in the coming years (Nalysnyk et al. Heart 89:767–772, 2003). In this chapter we will be discussing the complications of CABG surgery.
Her Majesty the Queen in Right of United Kingdom
####Daniela Graf on 2013-11-19 17:09:50####
Similar content being viewed by others
Abbreviations
- Intra-aortic balloon pump (IABP):
-
This is a device that is positioned in the descending aorta. It inflates in diastole thereby reducing the work of the heart/impedance by reducing the afterload and improves coronary circulation (Bojar 2011; Chikwe et al. 2006).
- Cardiopulmonary bypass (CPB):
-
This machine is used to perfuse organs during cardioplegic cardiac arrest during cardiac surgery. It includes heparinized circuit of a venous pipe and an arterial pipe, a mechanical pump, a blood reservoir, and an oxygenator. The venous pipe takes blood from the right heart. The blood is oxygenated and pumped back into the body via the arterial pipe (Bojar 2011).
- Deep hypothermic circulatory arrest:
-
In cardiac surgery patients who undergo major aortic procedures, e.g., arch surgery, and run the risk of cerebral hypoperfusion/injury undergo circulatory arrest with cooling to as low as 18°. With every 10° C of temperature reduction, there is 50 % reduction in cellular metabolism, thereby reducing the risk of ischemic injury to the brain (Bojar 2011).
- Cardioplegia:
-
A cold (4° C), high potassium content solution given at the time of cardiopulmonary bypass surgery to cause a diastolic cardiac arrest. The fluid leads to significant reduction in myocardial cellular metabolism and thereby reducing cardiac ischemia during the operation. The fluid also contains nutrition necessary for the myocardial cell survival (Bojar 2011; Chikwe et al. 2006).
References
Baerman JM, Kirsh MM, de Buitleir M, Hyatt L, Juni JE, Pitt E et al (1987) Natural history of determinants of conduction defects following coronary artery bypass surgery. Ann Thorac Surg 44(2):150–153
Blessing F, Jaeger BR, Oberhoffer M, Reichart B, Seidel D (2003) Prevention of early graft occlusion after coronary bypass grafting by post-operative reduction of plasma fibrinogen by H.E.L.P. apheresis. Z Kardiol 92(3):42–47
Bojar RM (2011) Manual of perioperative care in adult cardiac surgery, 5th edn. Wiley, Oxford
Borger MA, Rao V, Weisel RD, Ivanov J, Cohen G, Scully HE et al (1998) Deep sternal wound infection: risk factors and outcomes. Ann Thorac Surg 65(4):1050–1056
Bouchard D, Carrier M, Demers P, Cartier R, Pellerin M, Perrault LP et al (2010) Statin in combination with beta-blocker therapy reduces postoperative stroke after coronary artery bypass surgery. Ann Thorac Surg 91(3):645–659
Chaudhuri A, Shekar K, Coulter C (2012) Postoperative deep sternal wound infection: making an early microbiological diagnosis. Eur J Cardiothorac Surg 41(6):1304–1308
Chikwe J, Beddow E, Glenville B (2006) Cardiothoracic surgery. Oxford University Press, Oxford
de Oliveira Sá MPB, Nogueira JRC, Ferraz PE, Figueiredo OJ, Cavalcante WCP, Cavalcante TCP et al (2012) Risk factors for low cardiac output syndrome after coronary artery bypass grafting surgery. Rev Bras Cir Cardiovasc 27(2):217–223
Dyke CM, Bhatia D, Lorenz TJ, Marso SP, Tardiff BE, Hogeboom C et al (2000) Immediate coronary artery bypass surgery after platelet inhibition with eptifibatide: results from PURSUIT. Ann Thorac Surg 70(3):866–871
Friberg O, Svedjeholm R, Kallman J, Soderguist B (2007) Incidence, microbiological findings and clinical presentation of sternal wound infection after cardiac surgery with or without local gentamicin prophylaxis. Eur J Clin Microbiol Infect Dis 26(2):91–97
Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM (1988) CDC definitions of nosocomial infections, 1988. Am J Infect Control 16(3):128–140
Khorsandi M, Muhammad I, Shaikhrezai K, Pessotto R (2012) Is it worth placing ventricular pacing wires in all patients post-coronary artery bypass grafting? Interact Cardiovasc Thorac Surg 15(3):489–493
Klein A, Vuylsteke A, Nashef SAM (2008) Core topics in cardiothoracic critical care. Cambridge University Press, Cambridge
Kumar G, Iyer PU (2010) Management of perioperative low cardiac output state without extracorporeal life support: What is feasible? Ann Pediatr Cardiol 3(2):147–158
Lador A, Nasir H, Mansur N, Sharoni E, Biderman P, Leibovici L et al (2012) Antibiotic prophylaxis in cardiac surgery: systematic review and meta-analysis. J Antimicrob Chemother 67(3):541–550
Li Y, Walicki D, Mathiesen C, Jenny D, Li Q, Isayev Y et al (2009) Strokes after cardiac surgery and relationship to carotid stenosis. JAMA 66(9):1091–1096
Lu JCY, Grayson AD, Jha P, Srinivasan AK, Fabri BM (2003) Risk factors for sternal wound infection and mid-term survival following coronary artery bypass surgery. Eur J Cardiothorac Surg 23:943–949
Maganti MD, Rao V, Borger MA, Ivanov J, TE D (2005) Predictors of low cardiac output syndrome after isolated aortic valve surgery. Circulation 112:448–452
Mauerman WJ, Sampathkumar P (2008) Sternal wound infections. Best Pract Res Clin Anesthesiol 22(3):423–436
Mehran R, Rao SV, Bhatt DL, Gibson M, Caixeta A, Eikelboom J et al (2011) Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the bleeding academic research consortium. Circulation 123:2736–2747
Pires LA, Wagshal AB, Lancey R, Huang SKS (1995) Arrhythmias and conduction disturbances after coronary artery bypass graft surgery: epidemiology, management, and prognosis. Am Heart J 129(4):799–808
Rao V, Ivanov J, RD W, Ikonomidis JS, Christakis GT, David TE (1996) Predictors of low cardiac output syndrome after coronary artery bypass. J Thorac Cardiovasc Surg 112(1):38–51
Rasmussen C, Thiis JJ, Clemmensen P, Efsen F, Arendrup HC, Saunamäki K et al (1997) Significance and management of early graft failure after coronary artery bypass grafting feasibility and results of acute angiography and re-vascularization. Eur J Cardiothorac Surg 12:847–852
Ricotta JJ, Faggioli GL, Castilone A, Hassett JM (1994) Risk factors for stroke after cardiac surgery: buffalo cardiac-cerebral study group. J Vasc Surg 21(2):359–364
Rosseel PMJ, Santman FW, Bouter F, Dott CS (1997) Postcardiac surgery low cardiac output syndrome: dopexamine or dobutamine? Intensive Care Med 23:962–968
Selnes OA, Gottesman RF, Grega MA, Baumgartner WA, Zeger SL, McKhann GM (2012) Cognitive and neurological outcomes after coronary-artery bypass surgery. New England J Med 366(3):250–257
Singh K, Anderson E, Harper JG (2011) Overview and management of sternal wound infection. Semin Plast Surg 25(1):25–33
Storey RF (2011) Early mechanisms of graft occlusion. J Am Coll Cardiol 57(9):1078–1080
Tang GHL, Maganti M, Weisel RD, Borger MA (2004) Prevention and management of deep sternal wound infection. Semin Thorac Cardiovasc Surg 16(1):62–69
Tarakji KG, Sabik JF, Bhudia SK, Batizy LH, Blackstone EH (2011) Temporal onset, risk factors, and outcomes associated with stroke after coronary artery bypass grafting. JAMA 305(4):381–390
Toumpoulis IK, Anagnostopoulos CE, DeRose JJ, Swistel DG (2005) The impact of deep sternal wound infection on long term survival after coronary artery bypass grafting. Chest 127:464–471
Walts AE, Fishbein MC, Sustaita H, Matloff JM (1982) Ruptured atheromatous plaques in saphenous vein coronary artery bypass grafts: a mechanism of acute, thrombotic, late graft occlusion. Circulation 65(1):197–201
Wijns W, Kolh P, Danchin N, Di Mario C, Falk V, Folliguet T et al (2010) The guidelines on myocardial revascularization. Eur Heart J 31:2501–2555
Williams NS, Bulstrode CJK, O’Connell PR (2010) Bailey & love’s short practice of surgery, 25th edn. Hodder Arnold, London
Zhao DX, Leacche M, Balaguer JM, Boudoulas KD, Damp JA, Greelish JP et al (2008) Routine intraoperative completion angiography after coronary artery bypass grafting and 1-stop hybrid revascularization results from a fully integrated hybrid catheterization laboratory/operating room. J Am Coll Cardiol 53(3):232–241
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Her Majesty the Queen in Right of United Kingdom
About this entry
Cite this entry
Khorsandi, M., Shaikhrezai, K., Zamvar, V. (2014). Complications of Coronary Artery Bypass Grafting Surgery. In: Lanzer, P. (eds) PanVascular Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37393-0_233-1
Download citation
DOI: https://doi.org/10.1007/978-3-642-37393-0_233-1
Received:
Accepted:
Published:
Publisher Name: Springer, Berlin, Heidelberg
Online ISBN: 978-3-642-37393-0
eBook Packages: Springer Reference MedicineReference Module Medicine
Publish with us
Chapter history
-
Latest
Complications of Coronary Artery Bypass Grafting Surgery- Published:
- 08 July 2014
DOI: https://doi.org/10.1007/978-3-642-37393-0_233-2
-
Original
Complications of Coronary Artery Bypass Grafting Surgery- Published:
- 08 April 2014
DOI: https://doi.org/10.1007/978-3-642-37393-0_233-1