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Platelet Function in Hemostasis and Inherited Disorders of Platelet Number and Function

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Concise Guide to Hematology

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Abstract

Hemostasis encompasses mechanisms that lead to cessation of bleeding following injury and involves a series of interrelated and simultaneously occurring events involving the blood vessel, platelets, and plasma coagulation system. Platelets are anucleate fragments derived from megakaryocytes and have major roles in hemostasis. This chapter focuses on platelet structure and function and on inherited disorders of platelet number and function, which are generally associated with an increased bleeding risk with hemostatic challenges.

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Authors and Affiliations

  1. Sol Sherry Thrombosis Research Center and Department of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA

    A. Koneti Rao

  2. Department of Medicine, Penn State College of Medicine, Hershey, PA, USA

    Natthapol Songdej

Authors
  1. A. Koneti Rao
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  2. Natthapol Songdej
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Correspondence to A. Koneti Rao .

Editor information

Editors and Affiliations

  1. Department of Medicine, Case Western Reserve University, Cleveland, OH, USA

    Hillard M. Lazarus

  2. Department of Medicine, University Hospital Cleveland Medical Center, Cleveland, OH, USA

    Alvin H. Schmaier

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Rao, A.K., Songdej, N. (2019). Platelet Function in Hemostasis and Inherited Disorders of Platelet Number and Function. In: Lazarus, H., Schmaier, A. (eds) Concise Guide to Hematology. Springer, Cham. https://doi.org/10.1007/978-3-319-97873-4_14

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  • DOI: https://doi.org/10.1007/978-3-319-97873-4_14

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-97872-7

  • Online ISBN: 978-3-319-97873-4

  • eBook Packages: MedicineMedicine (R0)

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