SpringerLink
Log in

Noninvasive Ventilation in Patients with Solid Malignancies

  • Chapter
Noninvasive Mechanical Ventilation

  • 3399 Accesses

Abstract

Acute respiratory failure (ARF) refers to a rapidly progressive inability of the respiratory system to perform one or both of its gas exchange functions, which includes oxygenation and carbon dioxide elimination. This is usually life threatening especially when it occurs in patients with underlying malignancy. In patients with acute leukemia or lymphoma, the incidence of ARF ranges from 10 to 20 % and increases to 40 % in those with neutropenia or bone marrow transplantation [1, 2]. ARF in patients with solid tumors has a lower incidence of about 1–5 %, with about 44–50 % mortality when these patients were admitted to the intensive care unit (ICU) and required some form of ventilation [3–6]. Recent studies have shown that, in patients with ARF, noninvasive ventilation (NIV) can prevent the need for invasive mechanical ventilation, hence reducing the risks associated with this form of ventilation as well as reducing ICU and hospital stay [7–10]. There have also been reports of lower 30-day mortality with the use of NIV compared with invasive mechanical ventilation [11]. The purpose of this chapter is to provide an overview of the use of NIV in patients with solid malignancies emphasizing on indications and outcome.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Lemiale V, et al. Identifying cancer subjects with acute respiratory failure at high risk for intubation and mechanical ventilation. Respir Care. 2014;59(10):1517–23.

    Article  PubMed  Google Scholar 

  2. Chaoui D, et al. Incidence and prognostic value of respiratory events in acute leukemia. Leukemia. 2004;18(4):670–5.

    Article  CAS  PubMed  Google Scholar 

  3. Muller AM, Gazzana MB, Silva DR. Outcomes for patients with lung cancer admitted to intensive care units. Rev Bras Ter Intensiva. 2013;25(1):12–6.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Azoulay E. A new standard of care for critically ill patients with cancer. Chest. 2014;146(2):241–4.

    Article  PubMed  Google Scholar 

  5. Azoulay E, et al. The prognosis of acute respiratory failure in critically ill cancer patients. Medicine (Baltimore). 2004;83(6):360–70.

    Article  Google Scholar 

  6. Azoulay E, Schlemmer B. Diagnostic strategy in cancer patients with acute respiratory failure. Intensive Care Med. 2006;32(6):808–22.

    Article  PubMed  Google Scholar 

  7. Gristina GR, et al. Noninvasive versus invasive ventilation for acute respiratory failure in patients with hematologic malignancies: a 5-year multicenter observational survey. Crit Care Med. 2011;39(10):2232–9.

    Article  PubMed  Google Scholar 

  8. Conti G, et al. Noninvasive ventilation for the treatment of acute respiratory failure in patients with hematologic malignancies: a pilot study. Intensive Care Med. 1998;24(12):1283–8.

    Article  CAS  PubMed  Google Scholar 

  9. Rabbat A, et al. Prognosis of patients with acute myeloid leukaemia admitted to intensive care. Br J Haematol. 2005;129(3):350–7.

    Article  PubMed  Google Scholar 

  10. Hilbert G, et al. Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure. N Engl J Med. 2001;344(7):481–7.

    Article  CAS  PubMed  Google Scholar 

  11. Turkoglu M, et al. Acute respiratory distress syndrome in patients with hematological malignancies. Hematology. 2013;18(3):123–30.

    Article  PubMed  Google Scholar 

  12. Sirithanakul K, et al. Pulmonary complications following hematopoietic stem cell transplantation: diagnostic approaches. Am J Hematol. 2005;80(2):137–46.

    Article  PubMed  Google Scholar 

  13. Soares M, et al. Characteristics and outcomes of cancer patients requiring mechanical ventilatory support for >24 hrs. Crit Care Med. 2005;33(3):520–6.

    Article  PubMed  Google Scholar 

  14. Tognet E, et al. Treatment of acute respiratory failure with non-invasive intermittent positive pressure ventilation in haematological patients. Clin Intensive Care. 1994;5(6):282–8.

    CAS  PubMed  Google Scholar 

  15. Hilbert G, et al. Noninvasive continuous positive airway pressure in neutropenic patients with acute respiratory failure requiring intensive care unit admission. Crit Care Med. 2000;28(9):3185–90.

    Article  CAS  PubMed  Google Scholar 

  16. Azoulay E, et al. Improved survival in cancer patients requiring mechanical ventilatory support: impact of noninvasive mechanical ventilatory support. Crit Care Med. 2001;29(3):519–25.

    Article  CAS  PubMed  Google Scholar 

  17. Principi T, et al. Noninvasive continuous positive airway pressure delivered by helmet in hematological malignancy patients with hypoxemic acute respiratory failure. Intensive Care Med. 2004;30(1):147–50.

    Article  PubMed  Google Scholar 

  18. Rocco M, et al. Noninvasive ventilation by helmet or face mask in immunocompromised patients: a case-control study. Chest. 2004;126(5):1508–15.

    Article  PubMed  Google Scholar 

  19. Depuydt PO, et al. The impact of the initial ventilatory strategy on survival in hematological patients with acute hypoxemic respiratory failure. J Crit Care. 2010;25(1):30–6.

    Article  PubMed  Google Scholar 

  20. Mehta S, Hill NS. Noninvasive ventilation. Am J Respir Crit Care Med. 2001;163(2):540–77.

    Article  CAS  PubMed  Google Scholar 

  21. Azoulay E, et al. Acute respiratory distress syndrome in patients with malignancies. Intensive Care Med. 2014;40(8):1106–14.

    Article  PubMed  Google Scholar 

  22. Azevedo LC, et al. Outcomes for patients with cancer admitted to the ICU requiring ventilatory support: results from a prospective multicenter study. Chest. 2014;146(2):257–66.

    Article  PubMed  Google Scholar 

  23. Adda M, et al. Predictors of noninvasive ventilation failure in patients with hematologic malignancy and acute respiratory failure. Crit Care Med. 2008;36(10):2766–72.

    Article  PubMed  Google Scholar 

  24. British Thoracic Society Standards of Care Committee. Non-invasive ventilation in acute respiratory failure. Thorax. 2002;57(3):192–211.

    Article  Google Scholar 

  25. Hess DR. The evidence for noninvasive positive-pressure ventilation in the care of patients in acute respiratory failure: a systematic review of the literature. Respir Care. 2004;49(7):810–29.

    PubMed  Google Scholar 

  26. Skillrud DM, Offord KP, Miller RD. Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study. Ann Intern Med. 1986;105(4):503–7.

    Article  CAS  PubMed  Google Scholar 

  27. Tockman MS, et al. Airways obstruction and the risk for lung cancer. Ann Intern Med. 1987;106(4):512–8.

    Article  CAS  PubMed  Google Scholar 

  28. Vestbo J, et al. Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE). Eur Respir J. 2008;31(4):869–73.

    Article  CAS  PubMed  Google Scholar 

  29. Confalonieri M, et al. Acute respiratory failure in patients with severe community-acquired pneumonia. A prospective randomized evaluation of noninvasive ventilation. Am J Respir Crit Care Med. 1999;160(5 Pt 1):1585–91.

    Article  CAS  PubMed  Google Scholar 

  30. Ferrer M, et al. Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial. Am J Respir Crit Care Med. 2003;168(12):1438–44.

    Article  PubMed  Google Scholar 

  31. Organized jointly by the American Thoracic Society, the European Respiratory Society, the European Society of Intensive Care Medicine, and the Société de Réanimation de Langue Française, and approved by ATS Board of Directors. International Consensus Conferences in Intensive Care Medicine: noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med. 2001;163(1):283–91.

    Article  Google Scholar 

  32. Curtis JR, et al. Noninvasive positive pressure ventilation in critical and palliative care settings: understanding the goals of therapy. Crit Care Med. 2007;35(3):932–9.

    Article  PubMed  Google Scholar 

  33. Azoulay E, et al. Palliative noninvasive ventilation in patients with acute respiratory failure. Intensive Care Med. 2011;37(8):1250–7.

    Article  PubMed  Google Scholar 

  34. Nava S, Study Authors. Non-invasive ventilation for end-of-life oncology patients–authors’ reply. Lancet Oncol. 2013;14(6):e201.

    Article  PubMed  Google Scholar 

  35. Marik PE. Noninvasive positive-pressure ventilation in patients with malignancy. Am J Hosp Palliat Care. 2007;24(5):417–21.

    Article  PubMed  Google Scholar 

  36. Yu KY, et al. Noninvasive positive pressure ventilation for the treatment of acute respiratory distress syndrome following esophagectomy for esophageal cancer: a clinical comparative study. J Thorac Dis. 2013;5(6):777–82.

    PubMed Central  PubMed  Google Scholar 

  37. Lefebvre A, et al. Noninvasive ventilation for acute respiratory failure after lung resection: an observational study. Intensive Care Med. 2009;35(4):663–70.

    Article  PubMed  Google Scholar 

  38. Auriant I, et al. Noninvasive ventilation reduces mortality in acute respiratory failure following lung resection. Am J Respir Crit Care Med. 2001;164(7):1231–5.

    Article  CAS  PubMed  Google Scholar 

  39. Baumann HJ, Klose H, Simon M, Ghadban T, Braune SA, Hennigs JK, Kluge S. Fiberoptic bronchoscopy in patients with acute hypoxemic respiratory failure requiring noninvasive ventilation–a feasibility study. Crit Care. 2011;15(4):R179.

    Article  PubMed Central  PubMed  Google Scholar 

  40. Simon M, Braune S, Frings D, Wiontzek AK, Klose H, Kluge S. High-flow nasal cannula oxygen versus non-invasive ventilation in patients with acute hypoxaemic respiratory failure undergoing flexible bronchoscopy – a prospective randomised trial. Crit Care. 2014;18(6):712.

    Article  PubMed Central  PubMed  Google Scholar 

  41. Esquinas A, Zuil M, Scala R, Chiner E. Bronchoscopy during non-invasive mechanical ventilation: a review of techniques and procedures. Arch Bronconeumol. 2013;49(3):105–12.

    Article  PubMed  Google Scholar 

  42. Cabrini L, Esquinas A, Pasin L, Nardelli P, Frati E, Pintaudi M, Matos P, Landoni G, Zangrillo A. An international survey on noninvasive ventilation use for acute respiratory failure in general non-monitored wards. Respir Care. 2015;60(4):586–92.

    Article  PubMed  Google Scholar 

  43. Antonelli M, et al. A multiple-center survey on the use in clinical practice of noninvasive ventilation as a first-line intervention for acute respiratory distress syndrome. Crit Care Med. 2007;35(1):18–25.

    Article  PubMed  Google Scholar 

  44. Bello G, De Pascale G, Antonelli M. Noninvasive ventilation: practical advice. Curr Opin Crit Care. 2013;19(1):1–8.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University School of Medicine, Detroit, MI, USA

    Pascal Kingah MD & Ayman O. Soubani MD

  2. Medical ICU, Harper University Hospital, 3990 John R-3 Hudson, Detroit, MI, 48201, USA

    Ayman O. Soubani MD

  3. Pulmonary and Critical Care, Karmanos Cancer Center, Detroit, MI, USA

    Ayman O. Soubani MD

Authors
  1. Pascal Kingah MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ayman O. Soubani MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ayman O. Soubani MD .

Editor information

Editors and Affiliations

  1. Murcia, Spain

    Antonio M. Esquinas

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Kingah, P., Soubani, A.O. (2016). Noninvasive Ventilation in Patients with Solid Malignancies. In: Esquinas, A. (eds) Noninvasive Mechanical Ventilation. Springer, Cham. https://doi.org/10.1007/978-3-319-21653-9_67

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-21653-9_67

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-21652-2

  • Online ISBN: 978-3-319-21653-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation