SpringerLink
Log in

Quality of Life after Upper GI Surgery

  • Chapter
  • First Online:
Patient Reported Outcomes and Quality of Life in Surgery

  • 258 Accesses

Abstract

An accurate assessment of health-related quality of life (HRQL) in patients with upper gastroenterological complaints is essential in clinical decision making, by providing insights into patients’ experiences of the disease impact and its treatments on physical, social and emotional health. This may contribute to an improved understanding of the long-term impact of treatments and better comparisons of surgical and medical treatment alternatives. In the present chapter, we aim to assess the impact of upper GI surgery on patient health-related quality of life (HRQL), based on the available literature reports. An organ-based approach was followed to describe differing impacts on patients’ postoperative quality of life. An accurate assessment of HRQL in patients undergoing upper gastrointestinal surgery is an important prognostic tool in clinical decision making for this group of patients. Future research should focus on develo** HRQL guidelines and training programs, in order to carry out high-quality studies which can lead to improved understanding of this important postoperative parameter.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Free ship** worldwide - see info
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Huang ZD, Gu HY, Zhu J, Luo J, Shen XF, Deng QF, Zhang C, Li YB. The application of enhanced recovery after surgery for upper gastrointestinal surgery: meta-analysis. BMC Surg. 2020;20(1):3. https://doi.org/10.1186/s12893-019-0669-3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Carey S, Storey D, Biankin AV, Martin D, Young J, Allman-Farinelli M. Long term nutritional status and quality of life following major upper gastrointestinal surgery - a cross-sectional study. Clin Nutr. 2011;30(6):774–9. Epub 2011 Jul 1. https://doi.org/10.1016/j.clnu.2011.03.003.

    Article  PubMed  Google Scholar 

  3. McCulloch P, Ward J, Tekkis PP, ASCOT group of surgeons, British Oesophago-Gastric Cancer Group. Mortality and morbidity in gastro-oesophageal cancer surgery: initial results of ASCOT multicentre prospective cohort study. BMJ. 2003;327(7425):1192–7. https://doi.org/10.1136/bmj.327.7425.1192.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Allum WH, Bonavina L, Cassivi SD, et al. Surgical treatments for esophageal cancers. Ann N Y Acad Sci. 2014;1325:242–68. https://doi.org/10.1111/nyas.12533.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Karnofsky DA, Burchenal JH. In: Macleod CM, editor. Evaluation of chemotherapeutic agents. New York: Columbia University Press; 1949.

    Google Scholar 

  6. Schag CC, Heinrich RL, Ganz PA. Karnofsky performance status revisited: reliability, validity, and guidelines. J Clin Oncol. 1984;2:187–93.

    Article  CAS  PubMed  Google Scholar 

  7. Jacobs M, Macefield RC, Blazeby JM, Korfage IJ, van Berge Henegouwen MI, de Haes HC, Smets EM, Sprangers MA. Systematic review reveals limitations of studies evaluating health-related quality of life after potentially curative treatment for esophageal cancer. Qual Life Res. 2013;22(7):1787–803. https://doi.org/10.1007/s11136-012-0290-8.

    Article  PubMed  Google Scholar 

  8. Bottomley A, Aaronson NK, European Organisation for Research and Treatment of Cancer. International perspective on health-related quality-of-life research in cancer clinical trials: the European Organisation for Research and Treatment of Cancer experience. J Clin Oncol. 2007;25(32):5082–6. https://doi.org/10.1200/JCO.2007.11.3183.

    Article  PubMed  Google Scholar 

  9. Kluetz PG, Slagle A, Papadopoulos EJ, et al. Focusing on core patient-reported outcomes in cancer clinical trials: symptomatic adverse events, physical function, and disease-related symptoms. Clin Cancer Res. 2016;22:1553–8.

    Article  CAS  PubMed  Google Scholar 

  10. Brăgelmann R, Armbrecht U, Rosemeyer D, Schneider B, Zilly W, Stockbrügger RW. Nutrient malassimilation following total gastrectomy. Scand J Gastroenterol Suppl. 1996;218:26–33. https://doi.org/10.3109/00365529609094727.

    Article  PubMed  Google Scholar 

  11. Carey S, Laws R, Ferrie S, Young J, Allman-Farinelli M. Struggling with food and eating--life after major upper gastrointestinal surgery. Support Care Cancer. 2013;21(10):2749–57. https://doi.org/10.1007/s00520-013-1858-8.

    Article  PubMed  Google Scholar 

  12. Anandavadivelan P, Martin L, Djärv T, Johar A, Lagergren P. Nutrition impact symptoms are prognostic of quality of life and mortality after surgery for oesophageal cancer. Cancers (Basel). 2018;10(9):318. https://doi.org/10.3390/cancers10090318.

    Article  PubMed  Google Scholar 

  13. Aahlin EK, Tranø G, Johns N, Horn A, Søreide JA, Fearon KC, Revhaug A, Lassen K. Health-related quality of life, cachexia and overall survival after major upper abdominal surgery: a prospective cohort study. Scand J Surg. 2017;106(1):40–6. https://doi.org/10.1177/1457496916645962.

    Article  CAS  PubMed  Google Scholar 

  14. Lee MK, Yost KJ, Pierson KE, Blackmon SH. Patient-reported outcome domains for the esophageal CONDUIT report card: a prospective trial to establish domains. Health Qual Life Outcomes. 2018;16(1):197. https://doi.org/10.1186/s12955-018-1023-7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Viklund P, Wengstrom Y, Rouvelas I, Lindblad M, Lagergren J. Quality of life and persisting symptoms after oesophageal cancer surgery. Eur J Cancer. 2006;42(10):1407–14.

    Article  PubMed  Google Scholar 

  16. Chang YL, Tsai YF, Chao YK, Wu MY. Quality-of-life measures as predictors of post-esophagectomy survival of patients with esophageal cancer. Qual Life Res. 2016;25(2):465–75.

    Article  PubMed  Google Scholar 

  17. Davies AR, Pillai A, Sinha P, Sandhu H, Adeniran A, Mattsson F, Choudhury A, Forshaw MJ, Gossage JA, Lagergren J, et al. Factors associated with early recurrence and death after esophagectomy for cancer. J Surg Oncol. 2014;109(5):459–64.

    Article  PubMed  Google Scholar 

  18. Chang YL, Tsai YF, Wu YC, Hsieh MJ. Factors relating to quality of life after esophagectomy for cancer patients in Taiwan. Cancer Nurs. 2014;37(1):4–13.

    Article  PubMed  Google Scholar 

  19. Djarv T, Lagergren P. Six-month postoperative quality of life predicts long-term survival after oesophageal cancer surgery. Eur J Cancer. 2011;47(4):530–5.

    Article  PubMed  Google Scholar 

  20. Zieren HU, Jacobi CA, Zieren J, Müller JM. Quality of life following resection of oesophageal carcinoma. Br J Surg. 1996;83(12):1772–5. https://doi.org/10.1002/bjs.1800831235.

    Article  CAS  PubMed  Google Scholar 

  21. Viklund P, Lindblad M, Lagergren J. Influence of surgery-related factors on quality of life after esophageal or cardia cancer resection. World J Surg. 2005;29(7):841–8. https://doi.org/10.1007/s00268-005-7887-9.

    Article  PubMed  Google Scholar 

  22. Scarpa M, Saadeh LM, Fasolo A, Alfieri R, Cagol M, Cavallin F, et al. Health-related quality of life in patients with oesophageal cancer: analysis at different steps of the treatment pathway. J Gastrointest Surg. 2013;17:421–33. https://doi.org/10.1007/s11605-012-2069-1.

    Article  PubMed  Google Scholar 

  23. Huang Q, Zhong J, Yang T, Li J, Luo K, Zheng Y, et al. Impacts of anastomotic complications on the health-related quality of life after esophagectomy. J Surg Oncol. 2015;111(4):365–70. https://doi.org/10.1002/jso.23837.

    Article  PubMed  Google Scholar 

  24. Schandl A, Lagergren J, Johar A, Lagergren P. Health-related quality of life 10 years after oesophageal cancer surgery. Eur J Cancer. 2016;69:43–50. https://doi.org/10.1016/j.ejca.2016.09.032.

    Article  PubMed  Google Scholar 

  25. Markar SR, Zaninotto G, Castoro C, Johar A, Lagergren P, Elliott JA, Gisbertz SS, Mariette C, Alfieri R, Huddy J, Sounderajah V, Pinto E, Scarpa M, Klevebro F, Sunde B, Murphy CF, Greene C, Ravi N, Piessen G, Brenkman H, Ruurda JP, Van Hillegersberg R, Lagarde S, Wijnhoven B, Pera M, Roig J, Castro S, Matthijsen R, Findlay J, Antonowicz S, Maynard N, McCormack O, Ariyarathenam A, Sanders G, Cheong E, Jaunoo S, Allum W, Van Lanschot J, Nilsson M, Reynolds JV, van Berge Henegouwen MI, Hanna GB. Lasting symptoms after esophageal resection (LASER): European multicenter cross-sectional study. Ann Surg. 2022;275(2):e392–400. https://doi.org/10.1097/SLA.0000000000003917.

    Article  PubMed  Google Scholar 

  26. Boshier PR, Klevebro F, Savva KV, Waller A, Hage L, Hanna GB, Low DE. Assessment of health related quality of life and digestive symptoms in long-term, disease free survivors after esophagectomy. Ann Surg. 2022;275(1):e140–7. https://doi.org/10.1097/SLA.0000000000003829.

    Article  PubMed  Google Scholar 

  27. De Boer AG, Genovesi PI, Sprangers MA, Van Sandick JW, Obertop H, Van Lanschot JJ. Quality of life in long-term survivors after curative transhiatal oesophagectomy for oesophageal carcinoma. Br J Surg. 2000;87(12):1716–21. https://doi.org/10.1046/j.1365-2168.2000.01600.x.

    Article  PubMed  Google Scholar 

  28. Aghajanzadeh M, Safarpour F, Koohsari MR, et al. Functional outcome of gastrointestinal tract and quality of life after esophageal reconstruction of esophagus cancer. Saudi J Gastroenterol. 2009;15(1):24–8.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Tatematsu N, Hasegawa S, Tanaka E, Sakai Y, Tsuboyama T. Impact of oesophagectomy on physical fitness and health-related quality of life in patients with oesophageal cancer. Eur J Cancer Care. 2013b;22(3):308–13. https://doi.org/10.1111/ecc.12030.

    Article  CAS  Google Scholar 

  30. Malmström M, Klefsgard R, Ivarsson B, Roman M, Johansson J. Quality of life measurements as an indicator for timing of support after oesophagectomy for cancer: a prospective study. BMC Health Serv Res. 2015;15:96. https://doi.org/10.1186/s12913-015-0747-x.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Leibman S, Smithers BM, Gotley DC, Martin I, Thomas J. Minimally invasive esophagectomy: short- and long-term outcomes. Surg Endosc. 2006;20(3):428–33. https://doi.org/10.1007/s00464-005-0388-y.

    Article  CAS  PubMed  Google Scholar 

  32. Parameswaran R, Blazeby JM, Hughes R, Mitchell K, Berrisford RG, Wajed SA. Health-related quality of life after minimally invasive oesophagectomy. Br J Surg. 2010;97(4):525–31. https://doi.org/10.1002/bjs.6908.

    Article  CAS  PubMed  Google Scholar 

  33. de Boer AGEM, van Lanschot JJB, van Sandick JW, et al. Quality of life after transhiatal compared with extended transthoracic resection for adenocarcinoma of the esophagus. J Clin Oncol. 2004;22:4202–8.

    Article  PubMed  Google Scholar 

  34. Egberts JH, Schniewind B, Bestmann B, Schafmayer C, Egberts F, Faendrich F, et al. Impact of the site of anastomosis after oncologic esophagectomy on quality of life–a prospective, longitudinal outcome study. Ann Surg Oncol. 2008;15(2):566–75.

    Article  PubMed  Google Scholar 

  35. Wang H, Feng M, Tan L, Wang Q. Comparison of the short-term quality of life in patients with esophageal cancer after subtotal esophagectomy via video-assisted thoracoscopic or open surgery. Dis Esophagus. 2010;23(5):408–14. https://doi.org/10.1111/j.1442-2050.2009.01025.x.

    Article  PubMed  Google Scholar 

  36. Van Heijl M, Sprangers MAG, De Boer AGEM, Lagarde SM, Reitsma HB, Busch ORC, et al. Preoperative and early postoperative quality of life predict survival in potentially curable patients with esophageal cancer. Ann Surg Oncol. 2010;17(1):23–30. https://doi.org/10.1245/s10434-009-0731-y.

    Article  PubMed  Google Scholar 

  37. Sundaram A, Geronimo JC, Willer BL, et al. Survival and quality of life after minimally invasive esophagectomy: a single-surgeon experience. Surg Endosc. 2012;26(1):168–76.

    Article  PubMed  Google Scholar 

  38. Ramakrishnaiah V, Dash NR, Pal S, Sahni P, Kanti CT. Quality of life after oesophagectomy in patients with carcinoma of oesophagus: a prospective study. Indian J Cancer. 2014;51:346–51. https://doi.org/10.4103/0019-509X.146750.

    Article  PubMed  Google Scholar 

  39. Sugawara K, Yoshimura S, Yagi K, Nishida M, Aikou S, Yamagata Y, et al. Long-term health-related quality of life following robot-assisted radical transmediastinal esophagectomy. Surg Endosc. 2019;34:1602. https://doi.org/10.1007/s00464-019-06923-7.

    Article  PubMed  Google Scholar 

  40. van der Sluis PC, van der Horst S, May AM, Schippers C, Brosens LAA, Joore HCA, Kroese CC, Haj Mohammad N, Mook S, Vleggaar FP, Borel Rinkes IHM, Ruurda JP, van Hillegersberg R. Robot-assisted minimally invasive thoracolaparoscopic esophagectomy versus open transthoracic esophagectomy for resectable esophageal cancer: a randomized controlled trial. Ann Surg. 2019;269(4):621–30. https://doi.org/10.1097/SLA.0000000000003031.

    Article  PubMed  Google Scholar 

  41. Sarkaria IS, Rizk NP, Goldman DA, Sima C, Tan KS, Bains MS, et al. Early quality of life outcomes after robotic-assisted minimally invasive and open esophagectomy. Ann Thorac Surg. 2019;108(3):920–8. https://doi.org/10.1016/j.Athoracsur.2018.11.075.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Eyck BM, Klevebro F, van der Wilk BJ, Johar A, Wijnhoven BPL, van Lanschot JJB, Lagergren P, Markar SR, Lagarde SM, LASER study group. Lasting symptoms and long-term health-related quality of life after totally minimally invasive, hybrid and open Ivor Lewis esophagectomy. Eur J Surg Oncol. 2022;48(3):582–8. https://doi.org/10.1016/j.ejso.2021.10.023.

    Article  PubMed  Google Scholar 

  43. Williams AM, Kathawate RG, Zhao L, Grenda TR, Bergquist CS, Brescia AA, Kilbane K, Barrett E, Chang AC, Lynch W, Lin J, Wakeam E, Lagisetty KH, Orringer MB, Reddy RM. Similar quality of life after conventional and robotic transhiatal esophagectomy. Ann Thorac Surg. 2022;113(2):399–405. https://doi.org/10.1016/j.athoracsur.2021.03.018.

    Article  PubMed  Google Scholar 

  44. Gawad KA, Hosch SB, Bumann D, et al. How important is the route of reconstruction after esophagectomy: a prospective randomized study. Am J Gastroenterol. 1999;94:1490–6.

    Article  CAS  PubMed  Google Scholar 

  45. Gradauskas P, Rubikas R, Saferis V. Changes in quality of life after esophageal resections for carcinoma. Medicina (Kaunas). 2006;42(3):187–94.

    PubMed  Google Scholar 

  46. Zeng J, Liu JS. Quality of life after three kinds of esophagectomy for cancer. World J Gastroenterol. 2012;18(36):5106–13.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Barbour AP, Cormack OMM, Baker PJ, Hirst J, Krause L, Brosda S, Thomas JM, Blazeby JM, Thomson IG, Gotley DC, Smithers BM. Long-term health-related quality of life following esophagectomy: a nonrandomized comparison of thoracoscopically assisted and open surgery. Ann Surg. 2017;265(6):1158–65. https://doi.org/10.1097/SLA.0000000000001899.

    Article  PubMed  Google Scholar 

  48. Wang H, Tan L, Feng M, Zhang Y, Wang Q. Comparison of the short-term health-related quality of life in patients with esophageal cancer with different routes of gastric tube reconstruction after minimally invasive esophagectomy. Qual Life Res. 2011;20(2):179–89. https://doi.org/10.1007/s11136-010-9742-1.

    Article  PubMed  Google Scholar 

  49. Rutegard M, Lagergren J, Rouvelas I, et al. Population-based study of surgical factors in relation to health-related quality of life after oesophageal cancer resection. Br J Surg. 2008;95(5):592–601.

    Article  CAS  PubMed  Google Scholar 

  50. Blazeby JM, Avery K, Sprangers M, Pikhart H, Fayers P, Donovan J. Health-related quality of life measurement in randomized clinical trials in surgical oncology. J Clin Oncol. 2006;24(19):3178–86.

    Article  PubMed  Google Scholar 

  51. van den Boorn HG, Stroes CI, Zwinderman AH, Eshuis WJ, Hulshof MCCM, van Etten-Jamaludin FS, Sprangers MAG, van Laarhoven HWM. Health-related quality of life in curatively-treated patients with esophageal or gastric cancer: a systematic review and meta-analysis. Crit Rev Oncol Hematol. 2020;154:103069. https://doi.org/10.1016/j.critrevonc.2020.103069.

    Article  PubMed  Google Scholar 

  52. Scarpa M, Valente S, Alfieri R, Cagol M, Diamantis G, Ancona E, Castoro C. Systematic review of health-related quality of life after esophagectomy for esophageal cancer. World J Gastroenterol. 2011;17(42):4660–74. https://doi.org/10.3748/wjg.v17.i42.4660.

    Article  PubMed  PubMed Central  Google Scholar 

  53. Blazeby JM, Alderson D, Winstone K, Steyn R, Hammerlid E, Arraras J, Farndon JR. Development of an EORTC questionnaire module to be used in quality of life assessment for patients with oesophageal cancer. The EORTC Quality of Life Study Group. Eur J Cancer. 1996;32A:1912–7.

    Article  CAS  PubMed  Google Scholar 

  54. Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30(6):473–83.

    Article  PubMed  Google Scholar 

  55. Jacobs M, Macefield RC, Elbers RG, Sitnikova K, Korfage IJ, Smets EM, Henselmans I, van Berge Henegouwen MI, de Haes JC, Blazeby JM, Sprangers MA. Meta-analysis shows clinically relevant and long-lasting deterioration in health-related quality of life after esophageal cancer surgery. Qual Life Res. 2014;23(4):1097–115. https://doi.org/10.1007/s11136-013-0545-z.

    Article  CAS  PubMed  Google Scholar 

  56. Donohoe CL, McGillycuddy E, Reynolds JV. Long-term health-related quality of life for disease-free esophageal cancer patients. World J Surg. 2011;35(8):1853–60. https://doi.org/10.1007/s00268-011-1123-6.

    Article  PubMed  Google Scholar 

  57. Bulamu NB, Chen G, Ratcliffe J, Schloite A, Bright T, Watson DI. Health-related quality of life associated with Barrett's esophagus and cancer. World J Surg. 2019;43(6):1554–62. https://doi.org/10.1007/s00268-019-04936-w.

    Article  PubMed  Google Scholar 

  58. Rutegård M, Lagergren J, Rouvelas I, Lindblad M, Blazeby JM, Lagergren P. Population-based study of surgical factors in relation to health-related quality of life after oesophageal cancer resection. Br J Surg. 2008;95(5):592–601. https://doi.org/10.1002/bjs.6021.

    Article  PubMed  Google Scholar 

  59. Derogar M, Orsini N, Sadr-Azodi O, Lagergren P. Influence of major postoperative complications on health-related quality of life among long-term survivors of esophageal cancer surgery. J Clin Oncol. 2012;30(14):1615–9. https://doi.org/10.1200/JCO.2011.40.3568.

    Article  PubMed  Google Scholar 

  60. Li Z, Cheng J, Zhang Y, Wen S, Lv H, Xu Y, Zhu Y, Zhang Z, Mu D, Tian Z. Comparison of up-front minimally invasive esophagectomy versus open esophagectomy on quality of life for esophageal squamous cell cancer. Curr Oncol. 2021;28(1):693–701. https://doi.org/10.3390/curroncol28010068.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  61. Akhtar NM, Chen D, Zhao Y, Dane D, Xue Y, Wang W, Zhang J, Sang Y, Chen C, Chen Y. Postoperative short-term outcomes of minimally invasive versus open esophagectomy for patients with esophageal cancer: an updated systematic review and meta-analysis. Thorac Cancer. 2020;11(6):1465–75. https://doi.org/10.1111/1759-7714.13413.

    Article  PubMed  PubMed Central  Google Scholar 

  62. Li Z, Cheng J, Zhang Y, et al. Comparison of up-front minimally invasive esophagectomy versus open esophagectomy on quality of life for esophageal squamous cell cancer. Curr Oncol. 2021;28(1):693–701. https://doi.org/10.3390/curroncol28010068.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  63. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.

    Article  PubMed  Google Scholar 

  64. Hu Y, Zaydfudim VM. Quality of life after curative resection for gastric cancer: survey metrics and implications of surgical technique. J Surg Res. 2020;251:168–79. https://doi.org/10.1016/j.jss.2020.02.005.

    Article  PubMed  PubMed Central  Google Scholar 

  65. Wu CW, Chiou JM, Ko FS, Lo SS, Chen JH, Lui WY, et al. Quality of life after curative gastrectomy for gastric cancer in a randomised controlled trial. Br J Cancer. 2008;98:54–9.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Davis JL, Ripley RT. Postgastrectomy syndromes and nutritional considerations following gastric surgery. Surg Clin North Am. 2017;97(2):277–93. https://doi.org/10.1016/j.suc.2016.11.005.

    Article  PubMed  Google Scholar 

  67. McCall MD, Graham PJ, Bathe OF. Quality of life: a critical outcome for all surgical treatments of gastric cancer. World J Gastroenterol. 2016;22(3):1101–13. https://doi.org/10.3748/wjg.v22.i3.1101.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  68. Avery K, Hughes R, McNair A, Alderson D, Barham P, Blazeby J. Health-related quality of life and survival in the 2 years after surgery for gastric cancer. Eur J Surg Oncol. 2010;36(2):148–54. https://doi.org/10.1016/j.ejso.2009.09.008.

    Article  CAS  PubMed  Google Scholar 

  69. Kong H, Kwon OK, Yu W. Changes of quality of life after gastric cancer surgery. J Gastric Cancer. 2012;12(3):194–200. https://doi.org/10.5230/jgc.2012.12.3.194.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Worster E, Liu X, Richardson S, Hardwick RH, Dwerryhouse S, Caldas C, Fitzgerald RC. The impact of prophylactic total gastrectomy on health-related quality of life: a prospective cohort study. Ann Surg. 2014;260:87–93.

    Article  PubMed  Google Scholar 

  71. Brenkman HJF, Tegels JJW, Ruurda JP, Luyer MDP, Kouwenhoven EA, Draaisma WA, van der Peet DL, Wijnhoven BPL, Stoot JHMB, van Hillegersberg R, LOGICA Study Group. Factors influencing health-related quality of life after gastrectomy for cancer. Gastric Cancer. 2018;21(3):524–32. https://doi.org/10.1007/s10120-017-0771-0.

    Article  PubMed  Google Scholar 

  72. Hoksch B, Ablassmaier B, Zieren J, Müller JM. Quality of life after gastrectomy: Longmire’s reconstruction alone compared with additional pouch reconstruction. World J Surg. 2002;26(3):335–41. https://doi.org/10.1007/s00268-001-0229-7.

    Article  PubMed  Google Scholar 

  73. Kinami S, Nakamura N, Zhiyong J, Miyata T, Fujita H, Takamura H, Ueda N, Iida Y, Kosaka T. Severity of postgastrectomy syndrome and quality of life after advanced gastric cancer radical gastrectomy. Mol Clin Oncol. 2020;13(2):133–40. https://doi.org/10.3892/mco.2020.2061.

    Article  PubMed  PubMed Central  Google Scholar 

  74. Park KB, Park JY, Lee SS, Kwon OK, Chung HY, Yu W. Impact of body mass index on the quality of life after total gastrectomy for gastric cancer. Cancer Res Treat. 2018;50(3):852–60. https://doi.org/10.4143/crt.2017.080.

    Article  PubMed  Google Scholar 

  75. Fuchs KH, Thiede A, Engemann R, Deltz E, Stremme O, Hamelmann H. Reconstruction of the food passage after total gastrectomy: randomized trial. World J Surg. 1995;19(5):698–705; discussion 705-6. https://doi.org/10.1007/BF00295908.

    Article  CAS  PubMed  Google Scholar 

  76. Svedlund J, Sullivan M, Liedman B, Lundell L. Long term consequences of gastrectomy for patient’s quality of life: the impact of reconstructive techniques. Am J Gastroenterol. 1999;94(2):438–45. https://doi.org/10.1111/j.1572-0241.1999.874_c.x.

    Article  CAS  PubMed  Google Scholar 

  77. Kalmár K, Cseke L, Zámbó K, Horváth OP. Comparison of quality of life and nutritional parameters after total gastrectomy and a new type of pouch construction with simple Roux-en-Y reconstruction: preliminary results of a prospective, randomized, controlled study. Dig Dis Sci. 2001;46(8):1791–6. https://doi.org/10.1023/a:1010634427766.

    Article  PubMed  Google Scholar 

  78. Wu CW, Chiou JM, Ko FS, Lo SS, Chen JH, Lui WY, Whang-Peng J. Quality of life after curative gastrectomy for gastric cancer in a randomised controlled trial. Br J Cancer. 2008;98(1):54–9. https://doi.org/10.1038/sj.bjc.6604097.

    Article  PubMed  PubMed Central  Google Scholar 

  79. Kobayashi D, Kodera Y, Fujiwara M, Koike M, Nakayama G, Nakao A. Assessment of quality of life after gastrectomy using EORTC QLQ-C30 and STO22. World J Surg. 2011;35(2):357–64. https://doi.org/10.1007/s00268-010-0860-2.

    Article  PubMed  Google Scholar 

  80. Kim AR, Cho J, Hsu YJ, Choi MG, Noh JH, Sohn TS, Bae JM, Yun YH, Kim S. Changes of quality of life in gastric cancer patients after curative resection: a longitudinal cohort study in Korea. Ann Surg. 2012;256(6):1008–13. https://doi.org/10.1097/SLA.0b013e31827661c9.

    Article  PubMed  Google Scholar 

  81. Munene G, Francis W, Garland SN, Pelletier G, Mack LA, Bathe OF. The quality of life trajectory of resected gastric cancer. J Surg Oncol. 2011;105:337–41.

    Article  PubMed  Google Scholar 

  82. Karanicolas PJ, Graham D, Gönen M, Strong VE, Brennan MF, Coit DG. Quality of life after gastrectomy for adenocarcinoma: a prospective cohort study. Ann Surg. 2013;257(6):1039–46. https://doi.org/10.1097/SLA.0b013e31828c4a19.

    Article  PubMed  Google Scholar 

  83. Namikawa T, Kitagawa H, Okabayashi T, Sugimoto T, Kobayashi M, Hanazaki K. Roux-en-Y reconstruction is superior to billroth I reconstruction in reducing reflux esophagitis after distal gastrectomy: special relationship with the angle of his. World J Surg. 2010;34(5):1022–7. https://doi.org/10.1007/s00268-010-0452-1.

    Article  PubMed  Google Scholar 

  84. Park KB, Park JY, Lee SS, Chung HY, Kwon OK. Chronological changes in quality of life and body composition after gastrectomy for locally advanced gastric cancer. Ann Surg Treat Res. 2020;98(5):262–9. https://doi.org/10.4174/astr.2020.98.5.262.

    Article  PubMed  PubMed Central  Google Scholar 

  85. Takiguchi N, Takahashi M, Ikeda M, Inagawa S, Ueda S, Nobuoka T, Ota M, Iwasaki Y, Uchida N, Kodera Y, Nakada K. Long-term quality-of-life comparison of total gastrectomy and proximal gastrectomy by postgastrectomy syndrome assessment scale (PGSAS-45): a nationwide multi-institutional study. Gastric Cancer. 2015;18(2):407–16. https://doi.org/10.1007/s10120-014-0377-8.

    Article  PubMed  Google Scholar 

  86. van der Veen A, Brenkman HJF, Seesing MFJ, Haverkamp L, Luyer MDP, Nieuwenhuijzen GAP, Stoot JHMB, Tegels JJW, Wijnhoven BPL, Lagarde SM, de Steur WO, Hartgrink HH, Kouwenhoven EA, Wassenaar EB, Draaisma WA, Gisbertz SS, van der Peet DL, May AM, Ruurda JP, van Hillegersberg R, LOGICA Study Group. Laparoscopic versus open gastrectomy for gastric cancer (LOGICA): a multicenter randomized clinical trial. J Clin Oncol. 2021;39(9):978–89. https://doi.org/10.1200/JCO.20.01540.

    Article  CAS  PubMed  Google Scholar 

  87. Kim YW, Baik YH, Yun YH, Nam BH, Kim DH, Choi IJ, Bae JM. Improved quality of life outcomes after laparoscopy-assisted distal gastrectomy for early gastric cancer: results of a prospective randomized clinical trial. Ann Surg. 2008;248(5):721–7. https://doi.org/10.1097/SLA.0b013e318185e62e.

    Article  PubMed  Google Scholar 

  88. Takiguchi S, Yamamoto K, Hirao M, Imamura H, Fujita J, Yano M, Kobayashi K, Kimura Y, Kurokawa Y, Mori M, Doki Y, Osaka University Clinical Research Group for Gastroenterological Study. A comparison of postoperative quality of life and dysfunction after Billroth I and Roux-en-Y reconstruction following distal gastrectomy for gastric cancer: results from a multi-institutional RCT. Gastric Cancer. 2012;15(2):198–205. https://doi.org/10.1007/s10120-011-0098-1.

    Article  PubMed  Google Scholar 

  89. Lee MS, Ahn SH, Lee JH, Park DJ, Lee HJ, Kim HH, Yang HK, Kim N, Lee WW. What is the best reconstruction method after distal gastrectomy for gastric cancer? Surg Endosc. 2012;26(6):1539–47. https://doi.org/10.1007/s00464-011-2064-8.

    Article  PubMed  Google Scholar 

  90. Terashima M, Tanabe K, Yoshida M, Kawahira H, Inada T, Okabe H, Urushihara T, Kawashima Y, Fukushima N, Nakada K. Postgastrectomy Syndrome Assessment Scale (PGSAS)-45 and changes in body weight are useful tools for evaluation of reconstruction methods following distal gastrectomy. Ann Surg Oncol. 2014;21(Suppl 3):S370–8. https://doi.org/10.1245/s10434-014-3583-z.

    Article  PubMed  Google Scholar 

  91. Smolskas E, Lunevicius R, Samalavicius NE. Quality of life after subtotal gastrectomy for gastric cancer: does restoration method matter? - a retrospective cohort study. Ann Med Surg. 2015;4(4):371–5. https://doi.org/10.1016/j.amsu.2015.08.010.

    Article  Google Scholar 

  92. Hur H, Ahn CW, Byun CS, Shin HJ, Kim YB, Son SY, Han SU. A novel Roux-en-Y reconstruction involving the use of two circular staplers after distal subtotal gastrectomy for gastric cancer. J Gastric Cancer. 2017;17(3):255–66. https://doi.org/10.5230/jgc.2017.17.e32.

    Article  PubMed  PubMed Central  Google Scholar 

  93. Yang K, Zhang WH, Liu K, Chen XZ, Zhou ZG, Hu JK. Comparison of quality of life between Billroth-І and Roux-en-Y anastomosis after distal gastrectomy for gastric cancer: a randomized controlled trial. Sci Rep. 2017;7(1):11245. https://doi.org/10.1038/s41598-017-09676-2.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  94. Huang ZN, Huang CM, Zheng CH, Li P, **e JW, Wang JB, Lin JX, Lu J, Chen QY, Cao LL, Lin M, Tu RH, Lin JL. Digestive tract reconstruction using isoperistaltic jejunum-later-cut overlap method after totally laparoscopic total gastrectomy for gastric cancer: short-term outcomes and impact on quality of life. World J Gastroenterol. 2017;23(39):7129–38.

    Article  PubMed  PubMed Central  Google Scholar 

  95. Grosek J, Zavrtanik H, Tomažič A. Health-related quality of life after curative resection for gastric adenocarcinoma. World J Gastroenterol. 2021;27(16):1816–27. https://doi.org/10.3748/wjg.v27.i16.1816.

    Article  PubMed  PubMed Central  Google Scholar 

  96. van Amelsfoort RM, van der Sluis K, Schats W, Jansen EPM, van Sandick JW, Verheij M, Walraven I. Health-related quality of life in locally advanced gastric cancer: a systematic review. Cancers (Basel). 2021;13(23):5934. https://doi.org/10.3390/cancers13235934.

    Article  PubMed  PubMed Central  Google Scholar 

  97. Zeng F, Chen L, Liao M, Chen B, Long J, Wu W, Deng G. Laparoscopic versus open gastrectomy for gastric cancer. World J Surg Oncol. 2020;18(1):20. https://doi.org/10.1186/s12957-020-1795-1.

    Article  PubMed  PubMed Central  Google Scholar 

  98. Kim YW, Yoon HM, Yun YH, Nam BH, Eom BW, Baik YH, Lee SE, Lee Y, Kim YA, Park JY, Ryu KW. Long-term outcomes of laparoscopy-assisted distal gastrectomy for early gastric cancer: result of a randomized controlled trial (COACT 0301). Surg Endosc. 2013;27(11):4267–76. https://doi.org/10.1007/s00464-013-3037-x.

    Article  PubMed  Google Scholar 

  99. Lou S, Yin X, Wang Y, Zhang Y, Xue Y. Laparoscopic versus open gastrectomy for gastric cancer: a systematic review and meta-analysis of randomized controlled trials. Int J Surg. 2022;102:106678. https://doi.org/10.1016/j.ijsu.2022.106678.

    Article  PubMed  Google Scholar 

  100. Park S, Chung HY, Lee SS, Kwon O, Yu W. Serial comparisons of quality of life after distal subtotal or total gastrectomy: what are the rational approaches for quality of life management? J Gastric Cancer. 2014;14(1):32–8. https://doi.org/10.5230/jgc.2014.14.1.32.

    Article  PubMed  PubMed Central  Google Scholar 

  101. Conroy T, Marchal F, Blazeby JM. Quality of life in patients with oesophageal and gastric cancer: an overview. Oncology. 2006;70(6):391–402. https://doi.org/10.1159/000099034.

    Article  PubMed  Google Scholar 

  102. Dimenäs E. Methodological aspects of evaluation of quality of life in upper gastrointestinal diseases. Scand J Gastroenterol Suppl. 1993;199:18–21.

    Article  PubMed  Google Scholar 

  103. Romero M, Vivas-Consuelo D, Alvis-Guzman N. Is Health Related Quality of Life (HRQoL) a valid indicator for health systems evaluation? Springerplus. 2013;2(1):664. https://doi.org/10.1186/2193-1801-2-664.

    Article  PubMed  PubMed Central  Google Scholar 

  104. Zhang FF, Ye L, Yin N, **ong F, Zhao CH, Zhu YB. Evaluating health-related quality of life in gastric cancer patients in Suzhou, China. Ann Palliat Med. 2021;10(7):8024–33. https://doi.org/10.21037/apm-21-1599.

    Article  PubMed  Google Scholar 

  105. Park SH, Cho MS, Kim YS, Hong J, Nam E, Park J, Cho EK, Shin DB, Lee JH, Lee WK. Self-reported health-related quality of life predicts survival for patients with advanced gastric cancer treated with first-line chemotherapy. Qual Life Res. 2008;17(2):207–14. https://doi.org/10.1007/s11136-008-9307-8.

    Article  PubMed  Google Scholar 

  106. van Kleef JJ, Dijksterhuis WPM, van den Boorn HG, Prins M, Verhoeven RHA, Gisbertz SS, Slingerland M, Mohammad NH, Creemers GJ, Neelis KJ, Heisterkamp J, Rosman C, Ruurda JP, Kouwenhoven EA, van de Poll-Franse LV, van Oijen MGH, Sprangers MAG, van Laarhoven HWM, Dutch Upper GI Cancer Group (DUCG). Prognostic value of patient-reported quality of life for survival in oesophagogastric cancer: analysis from the population-based POCOP study. Gastric Cancer. 2021;24(6):1203–12. https://doi.org/10.1007/s10120-021-01209-1.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  107. Sherman RE, Anderson SA, Dal Pan GJ, Gray GW, Gross T, Hunter NL, LaVange L, Marinac-Dabic D, Marks PW, Robb MA, Shuren J, Temple R, Woodcock J, Yue LQ, Califf RM. Real-world evidence - what is it and what can it tell us? N Engl J Med. 2016;375(23):2293–7. https://doi.org/10.1056/NEJMsb1609216.

    Article  PubMed  Google Scholar 

  108. Ahmed M, Lau A, Hirpara DH, Kidane B. Choosing the right survey-patient reported outcomes in esophageal surgery. J Thorac Dis. 2020;12(11):6902–12. https://doi.org/10.21037/jtd.2020.03.58.

    Article  PubMed  PubMed Central  Google Scholar 

  109. Garratt AM, Ruta DA, Abdalla MI, Buckingham JK, Russell IT. The SF36 health survey questionnaire: an outcome measure suitable for routine use within the NHS? BMJ. 1993;306(6890):1440–4. https://doi.org/10.1136/bmj.306.6890.1440.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  110. Cella D, Riley W, Stone A, et al. The patient-reported outcomes measurement information system (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008. J Clin Epidemiol. 2010;63:1179–94.

    Article  PubMed  PubMed Central  Google Scholar 

  111. Smith AB, Cocks K, Parry D, Taylor M. Reporting of health-related quality of life (HRQOL) data in oncology trials: a comparison of the European Organization for Research and Treatment of Cancer Quality of Life (EORTC QLQ-C30) and the Functional Assessment of Cancer Therapy-General (FACT-G). Qual Life Res. 2014;23(3):971–6. https://doi.org/10.1007/s11136-013-0534-2.

    Article  PubMed  Google Scholar 

  112. Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, Silberman M, Yellen SB, Winicour P, Brannon J, et al. The functional assessment of cancer therapy scale: development and validation of the general measure. J Clin Oncol. 1993;11(3):570–9. https://doi.org/10.1200/JCO.1993.11.3.570.

    Article  CAS  PubMed  Google Scholar 

  113. Ter Veer E, van Kleef JJ, Sprangers MAG, Haj Mohammad N, van Oijen MGH, van Laarhoven HWM. Reporting of health-related quality of life in randomized controlled trials involving palliative systemic therapy for esophagogastric cancer: a systematic review. Gastric Cancer. 2018;21(2):183–95. https://doi.org/10.1007/s10120-018-0792-3.

    Article  PubMed  PubMed Central  Google Scholar 

  114. Lagergren P, Fayers P, Conroy T, Stein HJ, Sezer O, Hardwick R, Hammerlid E, Bottomley A, Van Cutsem E, Blazeby JM, European Organisation for Research Treatment of Cancer Gastrointestinal and Quality of Life Groups. Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-OG25, to assess health-related quality of life in patients with cancer of the oesophagus, the oesophago-gastric junction and the stomach. Eur J Cancer. 2007;43(14):2066–73. https://doi.org/10.1016/j.ejca.2007.07.005.

    Article  PubMed  Google Scholar 

  115. Blazeby JM, Farndon JR, Donovan J, Alderson D. A prospective longitudinal study examining the quality of life of patients with esophageal carcinoma. Cancer. 2000;88(8):1781–7.

    Article  CAS  PubMed  Google Scholar 

  116. Osoba D. Health-related quality of life and cancer clinical trials. Ther Adv Med Oncol. 2011;3(2):57–71. https://doi.org/10.1177/1758834010395342.

    Article  PubMed  PubMed Central  Google Scholar 

  117. Brundage M, Bass B, Davidson J, Queenan J, Bezjak A, Ringash J, et al. Patterns of reporting health-related quality of life outcomes in randomized clinical trials: implications for clinicians and quality of life researchers. Qual Life Res. 2011;20:653–64. https://doi.org/10.1007/s11136-010-9793-3.

    Article  PubMed  Google Scholar 

  118. Kyte D, Ives J, Draper H, Keeley T, Calvert M. Inconsistencies in quality of life data collection in clinical trials: a potential source of bias? Interviews with research nurses and trialists. PLoS One. 2013;8(10):e76625. https://doi.org/10.1371/journal.pone.0076625.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  119. Kesler KA. Measuring quality of life after esophagectomy: do we really need to go there? J Thorac Cardiovasc Surg. 2016;151(3):631–2. https://doi.org/10.1016/j.jtcvs.2015.08.111.

    Article  PubMed  Google Scholar 

  120. Alghamedi A, Buduhan G, Tan L, Srinathan SK, Sulman J, Darling G, Kidane B. Quality of life assessment in esophagectomy patients. Ann Transl Med. 2018;6(4):84. https://doi.org/10.21037/atm.2017.11.38.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, University Hospital of Larissa, Larissa, Greece

    Grigorios Christodoulidis & Athina A. Samara

  2. Faculty of Medicine, University of Thessaly, Larissa, Greece

    Michel B. Janho

Authors
  1. Grigorios Christodoulidis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Athina A. Samara
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Michel B. Janho
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Surgery and Cancer, Imperial College London, London, UK

    Thanos Athanasiou

  2. Surgery and Cancer, Imperial College London, London, UK

    Vanash Patel

  3. Surgery and Cancer, Imperial College London, London, UK

    Ara Darzi

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Christodoulidis, G., Samara, A.A., Janho, M.B. (2023). Quality of Life after Upper GI Surgery. In: Athanasiou, T., Patel, V., Darzi, A. (eds) Patient Reported Outcomes and Quality of Life in Surgery. Springer, Cham. https://doi.org/10.1007/978-3-031-27597-5_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-27597-5_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-27596-8

  • Online ISBN: 978-3-031-27597-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation