Abstract
The general architecture and cellular composition of the cerebellum is highly conserved within the vertebrate lineage enabling relevant comparative studies at gene and cell level. The zebrafish model is ideally suited for studies on cerebellar development and function as it’s rapid external development enable direct visualisation of cells and events at single cell resolution. Furthermore, the versatile toolbox for genetic manipulation to generate mutants and genetically encoded fluorescent reporters or sensors enables functional studies at cell, circuit and physiological level in vivo.
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Kaslin, J., Brand, M. (2023). The Zebrafish Cerebellum. In: Gruol, D.L., Koibuchi, N., Manto, M., Molinari, M., Schmahmann, J.D., Shen, Y. (eds) Essentials of Cerebellum and Cerebellar Disorders. Springer, Cham. https://doi.org/10.1007/978-3-031-15070-8_61
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