Abstract
Modern oncology places a high clinical necessity on the study of brain metastases. Brain metastases are by far the most prevalent intracranial tumors, and depending on the underlying primary tumor type, they can affect between 10% and 50% of cancer patients. The abundant blood supply provided by the brain microenvironment promotes tumor growth, and the blood-brain barrier prevents treatments from reaching the brain, reducing their efficacy. This chapter provides an overview of the different types of brain metastases using fifteen questions.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
Bibliography
Morgan AJ, Giannoudis A, Palmieri C. The genomic landscape of breast cancer brain metastases: a systematic review. Lancet Oncol. 2021;22(1):e7–e17. https://doi.org/10.1016/S1470-2045(20)30556-8.
Jaray H, Wang MD, Lily C. Brain metastases. Ferri’s Clinical Advisor. 2022:271–2.
Mayer SA, Marshall RS. Chapter 23: Neuroncology. In: On Call Neurology. Elsevier. p. 358–77.
Kotecha R, Ahluwalia MS, Siomin V, McDermott MW. Surgery, stereotactic radiosurgery, and systemic therapy in the Management of Operable Brain Metastasis. Neurol Clin. 2022;40(2):421–36. https://doi.org/10.1016/j.ncl.2021.11.002.
Ghiaseddin A, Peters KB. Use of bevacizumab in recurrent glioblastoma. CNS Oncol. 2015;4(3):157–69. https://doi.org/10.2217/cns.15.8.
Brem S, Desai A, Bagley SJ, Fan Y, Wong ET. Angiogenesis and brain tumors: scientific principles, current therapy, and future. Youmans Winn Neurol Surg. 140:970–970.e33.
Gondi V, Bauman G, Bradfield L, Burri SH, Cabrera AR, Cunningham DA, Eaton BR, Hattangadi-Gluth JA, Kim MM, Kotecha R, Kraemer L, Li J, Nagpal S, Rusthoven CG, Suh JH, Tomé WA, Wang TJC, Zimmer AS, Ziu M, Brown PD. Radiation therapy for brain metastases: an ASTRO clinical practice guideline. Pract Radiat Oncol. 2022;12(4):265–82. https://doi.org/10.1016/j.prro.2022.02.003. S1879-8500(22)00054-6, Epub ahead of print
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Das, J.M. (2023). Metastatic Brain Tumors. In: Neuro-Oncology Explained Through Multiple Choice Questions. Springer, Cham. https://doi.org/10.1007/978-3-031-13253-7_13
Download citation
DOI: https://doi.org/10.1007/978-3-031-13253-7_13
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-13252-0
Online ISBN: 978-3-031-13253-7
eBook Packages: MedicineMedicine (R0)