Abstract
Ginkgetin is the first known biflavonoid, isolated from the leaves of Ginkgo biloba L. after which it was named. It is a derivative of amentoflavone with two methoxy groups (7,4′-dimethylamentoflavone). Besides the ginkgo leaves, its presence has been confirmed in more than 20 other plant species, most of which are known in traditional medicine. For more than 30 years, it has been the focus of scientific attention as a possible effective anticancer agent and as an agent with beneficial effects on neurological diseases. This chapter summarizes the current data on the anticancer and neuroprotective effects of ginkgetin. In addition, information was provided on the potential anti-inflammatory, antiviral, antibacterial, antifungal, and antiparasitic effects of ginkgetin, as well as its potential role in cardiovascular health. At the end of the chapter, also its toxicology and safety are also discussed.
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Acknowledgments
This work has been supported by Croatian Science Foundation project “Biflavonoids role in plants: Ginkgo biloba L. as a model system” under the project no. UIP-2019-04-1018.
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Šamec, D., Jurčević-Šangut, I., Karalija, E. (2023). Ginkgetin: Advances on Resources, Bioactivity, and Pharmacology. In: **ao, J. (eds) Handbook of Dietary Flavonoids. Springer, Cham. https://doi.org/10.1007/978-3-030-94753-8_64-1
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Ginkgetin: Advances on Resources, Bioactivity, and Pharmacology- Published:
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DOI: https://doi.org/10.1007/978-3-030-94753-8_64-2
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Ginkgetin: Advances on Resources, Bioactivity, and Pharmacology- Published:
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DOI: https://doi.org/10.1007/978-3-030-94753-8_64-1