Artificial Iris Implantation: Overview of Surgical Techniques

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Cataract Surgery

Part of the book series: Essentials in Ophthalmology ((ESSENTIALS))

Abstract

Partial or total iris defects (aniridia), either congenital or acquired, may represent a therapeutic and surgical challenge. Not only present these patients with several visual disabilities and concomitant eye diseases (e.g., corneal opacity, cataract, glaucoma), they experience considerable aesthetic impairment. Recently, a new biocompatible foldable and custom-made silicon iris prosthesis was introduced (Customflex® Artificialiris; HumanOptics, Erlangen, Germany), which enabled development of new surgical techniques for the reconstruction of anterior segment in patients with iris defects in aphakic or pseudophakic eyes, whether with intact or compromised capsular support. Currently, several surgical techniques are reported for artificial iris implantation including implantation in the capsular bag or ciliary sulcus, four-floating suture technique, and scleral fixation techniques in combination with IOL implantation. This chapter provides a systematic overview of current surgical approaches for the artificial iris implantation with a thorough step-by-step technique description and case presentation including important surgical, pre- and postoperative considerations, and the reported cosmetic and functional results.

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References

  1. Samant M, Chauhan BK, Lathrop KL, Nischal KK. Congenital aniridia: etiology, manifestations and management. Expert Rev Ophthalmol. 2016;11:135–44.

    Article  Google Scholar 

  2. Riedl JC, Schuster AK, Vossmerbaeumer U. Indications and surgical techniques for implantation of the Artificial Iris®. Ophthalmologe. 2020;117:786–90.

    Article  Google Scholar 

  3. Yildirim TM, Khoramnia R, Masyk M, Son H-S, Auffarth GU, Mayer CS. Aesthetics of iris reconstruction with a custom-made artificial iris prosthesis. PLoS One. 2020;15:e0237616.

    Article  CAS  Google Scholar 

  4. Jung JW, Han SH, Kim SA, Kim EK, Seo KY, Kim T-I. Evaluation of pigment location in tinted soft contact lenses. Cont Lens Anterior Eye. 2016;39:210–6.

    Article  Google Scholar 

  5. Remky A, Redbrake C, Wenzel M. Intrastromal corneal tattooing for iris defects. J Cataract Refract Surg. 1998;24:1285–7.

    Article  CAS  Google Scholar 

  6. Burk SE, Da Mata AP, Snyder ME, Cionni RJ, Cohen JS, Osher RH. Prosthetic iris implantation for congenital, traumatic, or functional iris deficiencies. J Cataract Refract Surg. 2001;27:1732–40.

    Article  CAS  Google Scholar 

  7. Osher RH, Burk SE. Cataract surgery combined with implantation of an artificial iris. J Cataract Refract Surg. 1999;25:1540–7.

    Article  CAS  Google Scholar 

  8. Mayer C, Tandogan T, Hoffmann AE, Khoramnia R. Artificial iris implantation in various iris defects and lens conditions. J Cataract Refract Surg. 2017;43:724–31.

    Article  Google Scholar 

  9. Humanoptics. https://www.humanoptics.com/en/Humanoptics.

  10. Pozdeyeva NA, Pashtayev NP, Lukin VP, Batkov YN. Artificial iris-lens diaphragm in reconstructive surgery for aniridia and aphakia. J Cataract Refract Surg. 2005;31:1750–9.

    Article  Google Scholar 

  11. Https://www.reper.ru/irisReper.

  12. Walter T. Parker, David R. Hardten MES (2019) Iris prosthesis implantation. Video atlas of anterior segment repair and reconstruction. https://doi.org/10.1055/b-0039-172073.

  13. Na J-H, Park SC, Sohn Y, Lee S-D. Realizing the concept of a scalable artificial iris with self-regulating capability by reversible photoreaction of spiropyran dyes. Biomaterials. 2013;34:3159–64.

    Article  CAS  Google Scholar 

  14. Shareef FJ, Sun S, Kotecha M, Kassem I, Azar D, Cho M. Engineering a light-attenuating artificial iris. Investig Ophthalmol Vis Sci. 2016;57:2195–202.

    Article  CAS  Google Scholar 

  15. Koch KR, Heindl LM, Cursiefen C, Koch HR. Artificial iris devices: benefits, limitations, and management of complications. J Cataract Refract Surg. 2014;40:376–82.

    Article  Google Scholar 

  16. Bahadur GG, Miller KM. Artificial iris exchange. J Cataract Refract Surg. 2020;46:1630–6.

    Article  Google Scholar 

  17. https://clinicaltrials.gov/ct2/show/nct01860612. Safety and effectiveness of the customflex artificial iris prosthesis for the treatment of iris defects.

  18. https://www.Accessdata.Fda.Gov/Cdrh_Docs/Pdf17/P170039b.Pdf. Safety and effectiveness of the customflex artificial iris prosthesis for the treatment of iris defects.

  19. Figueiredo GB, Snyder ME. Long-term follow-up of a custom-made prosthetic iris device in patients with congenital aniridia. J Cataract Refract Surg. 2020;46:879–87.

    Article  Google Scholar 

  20. Mayer CS, Laubichler AE, Khoramnia R, Tandogan T, Prahs P, Zapp D, Reznicek L. Challenges and complication management in novel artificial iris implantation. J Ophthalmol. 2018;2018:3262068.

    Article  Google Scholar 

  21. Wolf A, Shajari M. Slip-and-slide technique for combined small-incision artificial iris and IOL implantation. J Cataract Refract Surg. 2020;46:1433–5.

    Article  Google Scholar 

  22. Magnus J, Trau R, Mathysen DGP, Tassignon M-J. Safety of an artificial iris in a phakic eye. J Cataract Refract Surg. 2012;38:1097–100.

    Article  Google Scholar 

  23. Rickmann A, Szurman P, Januschowski K, Waizel M, Spitzer MS, Boden KT, Szurman GB. Long-term results after artificial iris implantation in patients with aniridia. Graefe’s Arch Clin Exp Ophthalmol. 2016;254:1419–24.

    Article  CAS  Google Scholar 

  24. Bonnet C, Miller KM. Safety and efficacy of custom foldable silicone artificial iris implantation: prospective compassionate-use case series. J Cataract Refract Surg. 2020;46:893–901.

    Article  Google Scholar 

  25. Spitzer MS, Nessmann A, Wagner J, Yoeruek E, Bartz-Schmidt KU, Szurman P, Szurman GB. Customized humanoptics silicone iris prosthesis in eyes with posttraumatic iris loss: outcomes and complications. Acta Ophthalmol. 2016;94:301–6.

    Article  CAS  Google Scholar 

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Correspondence to Vladimir Pfeifer .

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Electronic Supplementary Materials

Capsular Bag Implantation with a Combined Standard Cataract Surgery (MP4 420567 kb)

Four floating Suture Technique (Pfeifer technique) (MP4 2320 kb)

Artificial iris implantation using 4-floating sutures technique (MP4 655462 kb)

AI and IOL implantation using Yamane technique (MP4 591890 kb)

AI Canabrava technique (MP4 497863 kb)

IA repositioning (MP4 36941 kb)

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Pfeifer, V., Marzidovšek, M., Lužnik, Z. (2022). Artificial Iris Implantation: Overview of Surgical Techniques. In: Alió, J.L., Dick, H.B., Osher, R.H. (eds) Cataract Surgery . Essentials in Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-030-94530-5_29

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  • DOI: https://doi.org/10.1007/978-3-030-94530-5_29

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-94529-9

  • Online ISBN: 978-3-030-94530-5

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