Abstract
The use of suspension dosage form has a long history for poorly soluble drugs. Development of stable suspension of the drug product has been a challenge on many fronts. In this chapter some of the important aspects of stable suspension formulation are discussed. Particularly, properties related to drug delivery and suspension stability are explained in detail. Suspension with regard to theoretical consideration including flocculation, viscosity, particle settling, zeta potential, Ostwald ripening, and particle aggregation is explained. Discussion relevant to excipients is also included. Moreover, methods of particle size reduction are introduced, including those employed for nanosuspension.
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Khan, S.A., Baseer, A., Khan, S., Hussain, M. (2022). Oral Suspensions. In: Khan, S.A. (eds) Essentials of Industrial Pharmacy. AAPS Advances in the Pharmaceutical Sciences Series, vol 46. Springer, Cham. https://doi.org/10.1007/978-3-030-84977-1_7
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DOI: https://doi.org/10.1007/978-3-030-84977-1_7
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