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COVID-19, Coenzyme Q10 and Selenium

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Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

Part of the book series: Advances in Experimental Medicine and Biology ((PMISB,volume 1327))

Abstract

In COVID-19 infection, a balance must be achieved in immune defence against the virus without precipitating a cytokine storm, which is responsible for lung injury and respiratory distress in severe cases. The initial immune response and the subsequent resolution of inflammation are likely to be dependent on nutritional status, as one contributing factor. Here, we have reviewed the potential link between two specific nutrients, coenzyme Q10 (CoQ10) and selenium, with effects on oxidative stress and inflammation in viral infection. We conclude that both reagents show promise in the treatment of patients with COVID-19 disease. This could give particular relevance over the next several months as promising vaccines are deployed to minimise the COVID-19 spread and as a potential preventative or mitigating approach for future epidemics and pandemics.

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Authors and Affiliations

  1. School of Pharmacy and Biomolecular Sciences, Liverpool John Moores, Liverpool, UK

    I. R. Hargreaves

  2. Pharma Nord (UK) Ltd, Morpeth, Newcastle, UK

    D. Mantle

Authors
  1. I. R. Hargreaves
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  2. D. Mantle
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Correspondence to I. R. Hargreaves .

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  1. Charlesworth House, Debden, Essex, UK

    Paul C. Guest

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Hargreaves, I.R., Mantle, D. (2021). COVID-19, Coenzyme Q10 and Selenium. In: Guest, P.C. (eds) Identification of Biomarkers, New Treatments, and Vaccines for COVID-19. Advances in Experimental Medicine and Biology(), vol 1327. Springer, Cham. https://doi.org/10.1007/978-3-030-71697-4_13

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