SpringerLink
Log in

A Patient with Low-Risk Papillary Thyroid Cancer Who Has Undergone a Lobectomy: Monitoring for Recurrent Disease and Assessment of Thyroid Function

  • Chapter
  • First Online:
Thyroid Cancer

  • 658 Accesses

Abstract

Differentiated thyroid cancer is increasing in incidence worldwide; however, most cases remain indolent and rarely life-threatening. For that reason, it is crucial to find the right extent of surgery and adjuvant treatment for each case, in order to avoid overtreatment and excessive morbidity due to the treatment and not to the disease itself. In this scenario, the American Thyroid Association guidelines, in 2015, recommended, based on several studies, that lobectomy could be sufficient as “curative” surgery for low-risk thyroid cancer. However, this approach led to some shift in concepts used during follow-up such as thyroglobulin levels and the frequency of ultrasounds. In this chapter, we present a case of a low-risk thyroid cancer treated with lobectomy to discuss how to follow and what to expect in terms of outcomes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
EUR 29.95
Price includes VAT (Germany)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
EUR 96.29
Price includes VAT (Germany)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
EUR 123.04
Price includes VAT (Germany)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info
Hardcover Book
EUR 171.19
Price includes VAT (Germany)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. http://www1.inca.gov.br/vigilancia/incidencia.asp

  2. Haymart MR, et al. Controversies in the management of low risk differentiated thyroid cancer. Endocr Rev. 2017;38(4):351–78.

    Article  Google Scholar 

  3. Haugen BR, et al. American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2016;26:1):1–133.

    Article  Google Scholar 

  4. Lang BH, et al. Lobectomy is a more cost-effective option than total thyroidectomy for 1-4cm papillary thyroid carcinoma that do not possess clinical recognizable high-risk features. Ann Surg Oncol. 2016;23(11):3641–52.

    Article  Google Scholar 

  5. Kwon H, et al. Comparison of lobectomy and total thyroidectomy in patients with papillary thyroid microcarcinoma – a retrospective individual risk factor-matches cohort study. Eur J Endocrinol. 2017;176(4):371–8.

    Article  CAS  Google Scholar 

  6. Vaisman F, Momesso D, Bulzico DA, Pessoa CH, da Cruz MD, Dias F, Corbo R, Vaisman M, Tuttle RM. Thyroid lobectomy is associated with excellent clinical outcomes in properly selected differentiated thyroid cancer patients with primary tumors greater than 1 cm. J Thyroid Res. 2013;2013:398194.

    Article  Google Scholar 

  7. Momesso DP, Vaisman F, Caminha LS, Pessoa CH, Corbo R, Vaisman M. Surgical approach and radioactive iodine therapy for small well-differentiated thyroid cancer. J Endocrinol Investig. 2014;37(1):57–64.

    Article  CAS  Google Scholar 

  8. Aschebrook-Kilfoy B, et al. Risk factors for decreased quality of life in thyroid cancer survivors: initial findings from the North American thyroid cancer survivorship study. Thyroid. 2015;25(12):1313–21.

    Article  Google Scholar 

  9. Zambeli-Ljepović A, Wang F, Dinan MA, Hyslop T, Roman SA, Sosa JA, Scheri RP. Low-risk thyroid cancer in elderly: total thyroidectomy/RAI predominates but lacks survival advantage. J Surg Res. 2019;243:189–97.

    Article  Google Scholar 

  10. Zambeli-Ljepović A, Wang F, Dinan MA, Hyslop T, Stang MT, Roman SA, Sosa JA, Scheri RP. Extent of surgery for low-risk thyroid cancer in the elderly: equipoise in survival but not in short-term outcome. Surgery. 2019;166(5):895–900.

    Article  Google Scholar 

  11. Schultz PN, et al. Health profiles and quality of life of 518 survivors of thyroid cancer. Head Neck. 2003;25(5):349–56.

    Article  Google Scholar 

  12. Lubitz CC, et al. Measurement and variation in estimation of quality of life effects of patients undergoing treatment for papillary thyroid carcinoma. Thyroid. 2017;27(2):197–206.

    Article  CAS  Google Scholar 

  13. Juxiang Gou MS, et al. Health-related quality of life assessment in surgical patients with papillary thyroid carcinoma – a single center analysis from mainland China. Medicine (Baltimore). 2017;96(38):e8070.

    Article  Google Scholar 

  14. Bayer MF, McDougall IR. Differences in radioimmunoassay results for thyroglobulin that effect management of patients with thyroid cancer. Clin Chem. 1984;30:81–6.

    Article  CAS  Google Scholar 

  15. Baskin HJ. Effect of postoperative 131I treatment on thy roglobulin measurements in the follow-up of patients with thyroid cancer. Thyroid. 1994;4:239–42.

    Article  CAS  Google Scholar 

  16. Van Herle AJ. Serum thyroglobulin measurement in the diagnosis and management of thyroid disease. Thyroid Today. 1981;4:1–5.

    Google Scholar 

  17. Mazzaferri EL. Treating high thyroglobulin with radioiodine: a magic bullet or a shot in the dark. J Clin Endocrinol Metab. 1995;80:1485–7.

    Article  CAS  Google Scholar 

  18. Momesso DP, Vaisman F, Yang SP, Bulzico DA, Corbo R, Vaisman M, Tuttle RM. Dynamic risk stratification in patients with differentiated thyroid cancer treated without radioactive iodine. J Clin Endocrinol Metab. 2016;101(7):2692–700.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Endocrinology, National cancer Institute- INCa, Universidade Federal do Rio de Janeiro- Medical School, Rio de Janeiro, RJ, Brazil

    Fernanda Vaisman

  2. Department of Endocrinology, Universidade Federal do Rio de Janeiro- Medical School, Rio de Janeiro, RJ, Brazil

    Marcela Vaisberg Cohen

Authors
  1. Fernanda Vaisman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Marcela Vaisberg Cohen
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

    Giorgio Grani

  2. Division of Endocrinology, Diabetes, and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

    David S. Cooper

  3. Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

    Cosimo Durante

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Vaisman, F., Cohen, M.V. (2021). A Patient with Low-Risk Papillary Thyroid Cancer Who Has Undergone a Lobectomy: Monitoring for Recurrent Disease and Assessment of Thyroid Function. In: Grani, G., Cooper, D.S., Durante, C. (eds) Thyroid Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-61919-0_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-61919-0_13

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-61918-3

  • Online ISBN: 978-3-030-61919-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation