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Nanoparticles and Their Application in Folklore Medicine as Promising Biotherapeutics

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Functional Bionanomaterials

Part of the book series: Nanotechnology in the Life Sciences ((NALIS))

Abstract

Folklore medicines have been used to treat numerous diseases and ailments since ancient times and have been recognized for their better remedial value due to fewer side effects compared to allopathic medicines. Folkloric medicines generally include decoctions and mixtures made from the extracts of parts of medicinal plants to make these herbal drugs. Herbal drugs have been recently getting more attention because of their potential to treat almost all diseases. However, there are a few drawbacks such as poor solubility, poor bioavailability, low oral absorption, and instability which have limited their use. In order to overcome these problems, nanoparticles have come into play. Nanotechnology and herbal science are integrated to overcome the limitations of using herbal drugs in a scientific way, for the development of novel drug delivery system for herbal drugs with a nano dose which aids in increasing the biosolubility and bioavailability, protection from toxicity, and persistent delivery. These nanosized drug delivery systems have predetermined rates and site precise action. In folklore medicine, nanoparticles containing bioactive therapeutic agents have acquired a great deal of implication due to their impending site-specific action and use in drug delivery. Metallic nanoparticles can also be synthesized from plants due to the inherent ability of plants to accumulate metal ions. A number of plant sources recognized for their use in traditional medicine are being used to synthesize therapeutic nanoparticles. The current review aims to summarize the application of nanotechnology in herbal medicine and the use of nanoparticles synthesized from plants as promising biotherapeutic agents in folklore medicine and presents an overview of the aspects of folkloric medicine in India.

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References

  • Ahmed I, Lakhani MS, Gillett M, John A, Raza H (2001) Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (karela) fruit extract in streptozotocin-induced diabetic rats. Diabetes Res Clin Pract 51:155–161

    Article  CAS  PubMed  Google Scholar 

  • Akhtar MS, Panwar J, Yun YS (2013) Biogenic synthesis of metallic nanoparticles by plant extracts. ACS Sustain Chem Eng 1:591–602

    Article  CAS  Google Scholar 

  • Alanazi FK, Radwan AA, Alsarra IA (2010) Biopharmaceutical applications of nanogold. Saudi Pharm J 18:179–193

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Alexis F, Pridgen E, Molnar LK, Farokhzad OC (2008) Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm 5:505–515

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Allen TM, Cullis PR (2004) Drug delivery systems: entering the mainstream. Science 303:1818–1822

    Article  CAS  PubMed  Google Scholar 

  • Anand R, Patnaik GK, Kamal R, Bhaduri AP (1995) Antioxaluric and anticalciuric activity of lupeol derivatives. Indian J Pharmacol 27:265

    CAS  Google Scholar 

  • Angajala G, Ramya R, Subashini R (2014) In-vitro anti-inflammatory and mosquito larvicidal efficacy of nickel nanoparticles phytofabricated from aqueous leaf extracts of Aegle marmelos Correa. Acta Trop 135:19–26

    Article  CAS  PubMed  Google Scholar 

  • Anjaria JV, Varia MR, Janakiraman K, Gulati OD (1975) Studies on Leptadenia reticulata: lactogenic effects on rats. Indian J Exp Biol 13(5):448–449

    CAS  PubMed  Google Scholar 

  • Ansari SH, Islam F, Sameem M (2012) Influence of nanotechnology on herbal drugs: a review. J Adv Pharm Technol Res 3(3):142–146

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Aromal SA, Philip D (2012) Green synthesis of gold nanoparticles using Trigonella foenum-graecum and its size-dependent catalytic activity. Spectrochim Acta A Mol Biomol Spectrosc 97:1–5

    Google Scholar 

  • Arunachalam KD, Annamalai SK (2013) Chrysopogon zizanioides aqueous extract mediated synthesis, characterization of crystalline silver and gold nanoparticles for biomedical applications. Int J Nanomedicine 8:2375

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Asha Rani PV, Low Kah Mun G, Hande MP, Valiyaveettil S (2008) Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano 3:279–290

    Article  CAS  Google Scholar 

  • Aziz N, Pandey R, Barman I, Prasad R (2016) Leveraging the attributes of Mucor hiemalis-derived silver nanoparticles for a synergistic broad-spectrum antimicrobial platform. Front Microbiol 7:1984. https://doi.org/10.3389/fmicb.2016.01984

  • Bakthavatchalam R, Blum CA, Brielmann H, Caldwell T, De Lombaert S, Hodgetts KJ, Zhen X (2004) 2-Substituted quinazoline-4-ylamine analogues as capsaicin receptor modulators. US Patent WO 55003: A1

    Google Scholar 

  • Bakthavatchatam R, Blum CL, Brielmann HL, Caldwell TM, Delombaert S, Hodgetis KJ, Yoon T, Zheng X (2003) Substituted quinazolin-4-ylamine analogues as modulators of capsaicin. WO 3:062209

    Google Scholar 

  • Balachandran P, Govindarajan R (2004) Hepatic disorders. In: Mishra LC (ed) Scientific basis for ayurvedic therapies. CRC Press, Boca Raton, FL, pp 232–250

    Google Scholar 

  • Baliga MS (2006) Mechanisms and pre-clinical efficacy of plants in preventing UV-induced skin damage: current status and future prospects. In: Sharma RK, Arora R (eds) Herbal drugs: a twenty first century perspective. JAYPEE, New Delhi, pp 497–521

    Google Scholar 

  • Bhattacharya S, Ghosh A (2009) Phytosomes: the emerging technology for enhancement of bioavailability of botanicals and nutraceuticals. Internet J Aesth Antiaging Med 2:141–153

    Google Scholar 

  • Bhattacharya R, Mukherjee P (2008) Biological properties of “naked” metal nanoparticles. Adv Drug Deliv Rev 60:1289–1306

    Article  CAS  PubMed  Google Scholar 

  • Bhumkar DR, Joshi HM, Sastry M, Pokharkar VB (2007) Chitosan reduced gold nanoparticles as novel carriers for transmucosal delivery of insulin. Pharm Res 24:1415–1426

    Article  CAS  PubMed  Google Scholar 

  • Billore KV, Yelne MB, Dennis TJ, Chaudhari BG (2004a) Kumkuma (Crocus sativus). Database on Medicinal Plants Used in Ayurveda Central Council for Research in Ayurveda and Siddha 6:110–132

    Google Scholar 

  • Billore KV, Yelne MB, Dennis TJ, Chaudhari BG (2004b) Vidari (Pueraria tuberosa). Database on Medicinal Plants Used in Ayurveda Central Council for Research in Ayurveda and Siddha 6:441–451

    Google Scholar 

  • Billore KV, Yelne MB, Dennis TJ, Chaudhari BG (2004c) Rohitaka (Tecomella undulata). Database on Medicinal Plants Used in Ayurveda Central Council for Research in Ayurveda and Siddha 6:321–329

    Google Scholar 

  • Bitencourt PER, Ferreira LM, Cargnelutti LO, Denardi L, Boligon A (2016) A new biodegradable polymeric nanoparticle formulation containing Syzygium cumini: phytochemical profile, antioxidant and antifungal activity and in vivo toxicity. Ind Crop Prod 83:400–407

    Google Scholar 

  • Bose BC, Vijayvargiya R, Saifi AQ, Sharma SK (1960) Some aspects of chemical and pharmacological studies of Acorus calamus Linn. J Am Pharm Assoc 49:32–34

    Article  CAS  Google Scholar 

  • Brayner R, Ferrari-Iliou R, Brivois N, Djediat S, Benedetti MF, Fiévet F (2006) Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. Nano Lett 6:866–870

    Article  CAS  PubMed  Google Scholar 

  • Brill RH, Cahill ND (1988) A red opaque glass from Sardis and some thoughts on red opaques in general. J Glass Stud 30:16–27

    Google Scholar 

  • Cai W, Gao T, Hong H, Sun J (2008) Applications of gold nanoparticles in cancer nanotechnology. Nanotechnol Sci Appl 1:17

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Campos DA, Madureira AR, Sarmento B, Gomes AM, Pintado MM (2015) Stability of bioactive solid lipid nanoparticles loaded with herbal extracts when exposed to simulated gastrointestinal tract conditions. Food Res Int 78:131–140

    Article  CAS  PubMed  Google Scholar 

  • Castro L, Blázquez ML, Muñoz JA, González F, García-Balboa C, Ballester A (2011) Biosynthesis of gold nanowires using sugar beet pulp. Process Biochem 46:1076–1082

    Article  CAS  Google Scholar 

  • Chakraborty B, Neogi NC (1978) Pharmacological properties of Tribulus terrestris L. Indian J Pharm Sci 40:50–52

    Google Scholar 

  • Chandra T (1978) Effect of Eclipta alba on inflammation and liver injury. Fitoterapia 58:23–31

    Google Scholar 

  • Chandran SP, Chaudhary M, Pasricha R, Ahmad A, Sastry M (2006) Synthesis of gold nanotriangles and silver nanoparticles using Aloe vera plant extract. Biotechnol Prog 22:577–583

    Article  CAS  PubMed  Google Scholar 

  • Chang CH, Huang WY, Lai CH, Hsu YM, Yao YH, Chen TY, Wu JY, Peng SF, Lin YH (2011) Development of novel nanoparticles shelled with heparin for berberine delivery to treat Helicobacter pylori. Acta Biomater 7:593–603

    Article  CAS  PubMed  Google Scholar 

  • Chaturvedi GN, Sharma BD (1975) Clinical studies on Hedychium spicatum (Shati): an antiasthmatic drug. J Res Indian Med 10:941

    Google Scholar 

  • Chaudhary H, Kohli K, Kumar V (2013) Nano-transfersomes as a novel carrier for transdermal delivery. Int J Pharm 454:367–380

    Article  CAS  PubMed  Google Scholar 

  • Chaudhary H, Kohli K, Kumar V (2014) A novel nano-carrier transdermal gel against inflammation. Int J Pharm 465:175–186

    Article  CAS  PubMed  Google Scholar 

  • Chen Y, Lin X, Park H, Greever R (2009) Study of artemisinin nanocapsules as anticancer drug delivery systems. Nanomedicine 5:316–322

    Article  CAS  PubMed  Google Scholar 

  • Chen ZH, Jie JS, Luo LB, Wang H, Lee CS, Lee ST (2007) Applications of silicon nanowires functionalized with palladium nanoparticles in hydrogen sensors. Nanotechnology 18:345502

    Article  CAS  Google Scholar 

  • Coccia F, Tonucci L, Bosco D, Bressan M, d’Alessandro N (2012) One-pot synthesis of lignin-stabilised platinum and palladium nanoparticles and their catalytic behaviour in oxidation and reduction reactions. Green Chem 14:1073–1078

    Article  CAS  Google Scholar 

  • Cohen MS, Stern JM, Vanni AJ, Kelley RS, Baumgart E, Field D, Libertino JA, Summerhayes IC (2007) In vitro analysis of a nanocrystalline silver-coated surgical mesh. Surg Infect 8:397–404

    Article  Google Scholar 

  • Cox SG, Cullingworth L, Rode H (2011) Treatment of paediatric burns with a nanocrystalline silver dressing compared with standard wound care in a burn’s unit: a cost analysis. S Afr Med J 101:728–731

    Google Scholar 

  • Cruz D, Falé PL, Mourato A, Vaz PD, Serralheiro ML, Lino AR (2010) Preparation and physicochemical characterization of Ag nanoparticles biosynthesized by Lippia citriodora (Lemon Verbena). Colloids Surf B: Biointerfaces 81:67–73

    Article  CAS  PubMed  Google Scholar 

  • Daisy P, Saipriya K (2012) Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus. Int J Nanomedicine 7:1189

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dandekar PP, Jain R, Patil S, Dhumal R, Tiwari D, Sharma S, Vanage G, Patravale V (2010) Curcumin-loaded hydrogel nanoparticles: application in anti-malarial therapy and toxicological evaluation. J Pharm Sci 99:4992–5010

    Article  CAS  PubMed  Google Scholar 

  • Das RK, Gogoi N, Bora U (2011) Green synthesis of gold nanoparticles using Nyctanthes arbortristis flower extract. Bioprocess Biosyst Eng 34:615–619

    Article  CAS  PubMed  Google Scholar 

  • D’cruz SC, Vaithinathan S, Jubendradass R, Mathur PP (2010) Effects of plants and plant products on the testis. Asian J Androl 12:468

    Article  PubMed  PubMed Central  Google Scholar 

  • Deka DK, Lahon LC, Saikia J, Mukit A (1994) Effect of Cissus quadrangularis in accelerating healing process of experimentally fractured radius-ulna of dog, a preliminary study. Indian J Pharmacol 26:44–45

    Google Scholar 

  • Devendra NK, Vijaykumar BM, Seetharam YN (2010) Folklore medicinal plants of Gulbarga District, Karnataka, India. e-J Indian Med 3:53–60

    Google Scholar 

  • Dilnawaz F, Sahoo SK (2013) Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model. Eur J Pharm Biopharm 85:452–462

    Article  CAS  PubMed  Google Scholar 

  • DiMauro TM, Codman (2013) Methylated curcumin-resveratrol hybrid molecules for treating cancer. United States patent US 8,350,093

    Google Scholar 

  • Dipankar C, Murugan S (2012) The green synthesis, characterization and evaluation of the biological activities of silver nanoparticles synthesized from Iresine herbstii leaf aqueous extracts. Colloids Surf B: Biointerfaces 98:112–119

    Article  CAS  PubMed  Google Scholar 

  • Dixit PP, Londhe JS, Ghaskadbi SS, Devasagayam TP (2006) Antidiabetic and related beneficial properties of Indian medicinal plants. In: Sharma RK, Arora R (eds) Herbal drugs: a twenty first century perspective. JAYPEE Brothers, New Delhi, pp 377–395

    Google Scholar 

  • Dubey SP, Lahtinen M, Särkkä H, Sillanpää M (2010) Bioprospective of Sorbus aucuparia leaf extract in development of silver and gold nanocolloids. Colloids Surf B: Biointerfaces 80:26–33

    Article  CAS  PubMed  Google Scholar 

  • Dutta NK, Iyer SN (1968) Anti-amoebic value of berberine and kurchi alkaloids. J Indian Med Assoc 50:349–352

    CAS  PubMed  Google Scholar 

  • Dwivedi AD, Gopal K (2010) Biosynthesis of silver and gold nanoparticles using Chenopodium album leaf extract. Colloids Surf A Physicochem Eng Asp 369:27–33

    Article  CAS  Google Scholar 

  • Fadeel B, Garcia-Bennett AE (2010) Better safe than sorry: understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. Adv Drug Deliv Rev 62:362–374

    Article  CAS  PubMed  Google Scholar 

  • Farooqi AA, Khan MM, Vasundhara M (2001) Production technology of medicinal and aromatic crops. Nat Remed 2001:90–91

    Google Scholar 

  • Gan PP, Ng SH, Huang Y, Li SF (2012) Green synthesis of gold nanoparticles using palm oil mill effluent (POME): a low-cost and eco-friendly viable approach. Bioresour Technol 113:132–135

    Article  CAS  PubMed  Google Scholar 

  • Gardea-Torresdey JL, Parsons JG, Gomez E, Peralta-Videa J, Troiani HE, Santiago P, Yacaman MJ (2002) Formation and growth of Au nanoparticles inside live alfalfa plants. Nano Lett 2:397–401

    Article  CAS  Google Scholar 

  • Geetha R, Ashokkumar T, Tamilselvan S, Govindaraju K, Sadiq M, Singaravelu G (2013) Green synthesis of gold nanoparticles and their anticancer activity. Cancer Nanotechnol 4:91–98

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Ghosh S, Patil S, Ahire M, Kitture R, Kale S, Pardesi K, Cameotra SS, Bellare J, Dhavale DD, Jabgunde A, Chopade BA (2012) Synthesis of silver nanoparticles using Dioscorea bulbifera tuber extract and evaluation of its synergistic potential in combination with antimicrobial agents. Int J Nanomedicine 7:483

    CAS  PubMed  PubMed Central  Google Scholar 

  • Gopidas KR, Whitesell JK, Fox MA (2003) Synthesis, characterization, and catalytic applications of a palladium-nanoparticle-cored dendrimer. Nano Lett 3:1757–1760

    Article  CAS  Google Scholar 

  • Govindarajan R, Vijayakumar M (2006) Anti-oxidant approach to diseases management with special emphasis on herbal drugs. In: Sharma RK, Arora R (eds) Herbal drugs: a twenty first century perspective. JAYPEE, New Delhi, pp 421–431

    Google Scholar 

  • Goyal M, Sasmal D, Nagori BP (2011) Review on medicinal plants used by local community of Jodhpur district of thar desert. Int J Pharmacol 7:333–339

    Article  Google Scholar 

  • Gugulothu D, Kulkarni A, Patravale V, Dandekar P (2014) pH-sensitive nanoparticles of curcumin–celecoxib combination: evaluating drug synergy in ulcerative colitis model. J Pharm Sci 103:687–696

    Article  CAS  PubMed  Google Scholar 

  • Gujral ML, Saxena PN, Mishra SS (1955) An experimental study of the comparative activity of indigenous diuretics. J Indian Med Assoc 25:49–51

    CAS  PubMed  Google Scholar 

  • Gupta SS, Gupta NK (1967) Effect of Solanum xanthocarpum and Clerodendron serratum on histamine release from tissues. Indian J Med Sci 21:795–799

    CAS  PubMed  Google Scholar 

  • Harne S, Sharma A, Dhaygude M, Joglekar S, Kodam K, Hudlikar M (2012) Novel route for rapid biosynthesis of copper nanoparticles using aqueous extract of Calotropis procera L. latex and their cytotoxicity on tumor cells. Colloids Surf B: Biointerfaces 95:284–288

    Article  CAS  PubMed  Google Scholar 

  • Harvey SK (1966) Preliminary experimental study of the diuretic activity of some indigenous drugs. Indian J Med Res 54:774–778

    Google Scholar 

  • Hazzah HA, Farid RM, Nasra MM, Hazzah WA, El-Massik MA, Abdallah OY (2015) Gelucire-based nanoparticles for curcumin targeting to oral mucosa: preparation, characterization, and antimicrobial activity assessment. J Pharm Sci 104:3913–3924

    Article  CAS  PubMed  Google Scholar 

  • Henkel RR, Wang R, Bassett SH, Chen T, Liu N, Zhu Y, Tambi MI (2014) Tongkat Ali as a potential herbal supplement for physically active male and female seniors – a pilot study. Phytother Res 28:544–550

    Article  PubMed  Google Scholar 

  • Hou J, Zhou SW (2008) Formulation and preparation of glycyrrhizic acid solid lipid nanoparticles. Acta Acad Med Militaris Tertiae 30:1043–1045

    CAS  Google Scholar 

  • Hrapovic S, Liu Y, Male KB, Luong JH (2004) Electrochemical biosensing platforms using platinum nanoparticles and carbon nanotubes. Anal Chem 76:1083–1088

    Article  CAS  PubMed  Google Scholar 

  • Huang Y, Li X, Liao Z, Zhang G, Liu Q, Tang J, Peng Y, Liu X, Luo Q (2007) A randomized comparative trial between acticoat and SD-Ag in the treatment of residual burn wounds, including safety analysis. Burns 33:161–166

    Article  PubMed  Google Scholar 

  • Iram F, Iqbal MS, Athar MM, Saeed MZ, Yasmeen A, Ahmad R (2014) Glucoxylan-mediated green synthesis of gold and silver nanoparticles and their phyto-toxicity study. Carbohydr Polym 104:29–33

    Article  CAS  PubMed  Google Scholar 

  • Iravani S (2011) Green synthesis of metal nanoparticles using plants. Green Chem 13:2638–2650

    Article  CAS  Google Scholar 

  • Islam NU, Jalil K, Shahid M, Muhammad N, Rauf A (2015) Pistacia integerrima gall extract mediated green synthesis of gold nanoparticles and their biological activities. Arab J Chem

    Google Scholar 

  • Jacob SJ, Finub JS, Narayanan A (2012) Synthesis of silver nanoparticles using Piper longum leaf extracts and its cytotoxic activity against Hep-2 cell line. Colloids Surf B: Biointerfaces 91:212–214

    Article  PubMed  CAS  Google Scholar 

  • Jain D, Daima HK, Kachhwaha S, Kothari SL (2009) Synthesis of plant-mediated silver nanoparticles using papaya fruit extract and evaluation of their antimicrobial activities. Dig J Nanomater Biostruct 4:557–563

    Google Scholar 

  • Jayaseelan C, Rahuman AA, Rajakumar G, Kirthi AV, Santhoshkumar T, Marimuthu S, Bagavan A, Kamaraj C, Zahir AA, Elango G (2011) Synthesis of pediculocidal and larvicidal silver nanoparticles by leaf extract from heartleaf moonseed plant, Tinospora cordifolia Miers. Parasitol Res 109:185–194

    Article  PubMed  Google Scholar 

  • Jayaseelan C, Ramkumar R, Rahuman AA, Perumal P (2013) Green synthesis of gold nanoparticles using seed aqueous extract of Abelmoschus esculentus and its antifungal activity. Ind Crop Prod 45:423–429

    Article  CAS  Google Scholar 

  • Joerger R, Klaus T, Granqvist CG (2000) Biologically produced silver–carbon composite materials for optically functional thin-film coatings. Adv Mater 12:407–409

    Article  CAS  Google Scholar 

  • Joshi PK (1998) Pharmaco-clinical study of Argavadha with special reference to vicharchika. M.D. (Ayu) dissertation, Gujarat Ayurved University, Jamnagar, India

    Google Scholar 

  • Joshi PK (2005) A comparative pharmacognostical, phytochemical and pharmacotherapeutic study of Shweta Musali (Curculigo orchioides) with special reference to Vrsya karma. Ph.D. (Ayu) thesis, Gujarat Ayurved University, Jamnagar, India

    Google Scholar 

  • Kale A, Bao Y, Zhou Z, Prevelige PE, Gupta A (2013) Directed self-assembly of CdS quantum dots on bacteriophage P22 coat protein templates. Nanotechnology 24:045603

    Article  PubMed  CAS  Google Scholar 

  • Kanazawa K (2009) Water-dispersible nanoparticle which contains blood circulation promoter. United States patent application US 12/252,589

    Google Scholar 

  • Kaviya S, Santhanalakshmi J, Viswanathan B, Muthumary J, Srinivasan K (2011) Biosynthesis of silver nanoparticles using Citrus sinensis peel extract and its antibacterial activity. Spectrochim Acta A Mol Biomol Spectrosc 79:594–598

    Article  CAS  PubMed  Google Scholar 

  • Kesarwani K, Gupta R (2013) Bioavailability enhancers of herbal origin: an overview. Asian Pac J Trop Biomed 3:253–266

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Khan AA, Fox EK, Górzny MŁ, Nikulina E, Brougham DF, Wege C, Bittner AM (2013) pH control of the electrostatic binding of gold and iron oxide nanoparticles to tobacco mosaic virus. Langmuir 29:2094–2098

    Article  CAS  PubMed  Google Scholar 

  • Khatoon N, Ahmad R, Sardar M (2015) Robust and fluorescent silver nanoparticles using Artemisia annua: biosynthesis, characterization and antibacterial activity. Biochem Eng J 102:91–97

    Article  CAS  Google Scholar 

  • Kim JS, Kuk E, Yu KN, Kim JH, Park SJ, Lee HJ, Kim SH, Park YK, Park YH, Hwang CY, Kim YK (2007) Antimicrobial effects of silver nanoparticles. Nanomedicine 3:95–101

    Article  CAS  PubMed  Google Scholar 

  • Kora AJ, Sashidhar RB, Arunachalam J (2012) Aqueous extract of gum olibanum (Boswellia serrata): a reductant and stabilizer for the biosynthesis of antibacterial silver nanoparticles. Process Biochem 47:1516–1520

    Article  CAS  Google Scholar 

  • Kostarelos K (2003) Rational design and engineering of delivery systems for therapeutics: biomedical exercises in colloid and surface science. Adv Colloid Interf Sci 106:147–168

    Article  CAS  Google Scholar 

  • Koul IB, Kapil A (1994) Effect of diterpenes from Andrographis paniculata on antioxidant defense system and lipid peroxidation. Indian J Pharmacol 26:296

    CAS  Google Scholar 

  • Kralj S, Makovec D (2015) Magnetic assembly of superparamagnetic iron oxide nanoparticle clusters into nanochains and nanobundles. ACS Nano 9:9700–9707

    Article  CAS  PubMed  Google Scholar 

  • Krishnaraj C, Jagan EG, Rajasekar S, Selvakumar P, Kalaichelvan PT, Mohan N (2010) Synthesis of silver nanoparticles using Acalypha indica leaf extracts and its antibacterial activity against water borne pathogens. Colloids Surf B: Biointerfaces 76:50–56

    Article  CAS  PubMed  Google Scholar 

  • Krishnaswamy M, Purushothaman KK (1980) Plumbagin: a study of its anticancer, antibacterial and antifungal properties. Indian J Exp Biol 18:876–877

    CAS  PubMed  Google Scholar 

  • Lee HJ, Lee G, Jang NR, Yun JH, Song JY, Kim BS (2011) Biological synthesis of copper nanoparticles using plants extract. Nanotechnology 1:371–374

    CAS  Google Scholar 

  • Leighton HJ, Frangakis GJ (2013) Methods and compositions for treating inflammation of skin. US Patent 20130059019

    Google Scholar 

  • Li W, Yi S, Wang Z, Chen S, **n S, **e J, Zhao C (2011a) Self-nanoemulsifying drug delivery system of persimmon leaf extract: optimization and bioavailability studies. Int J Pharm 420:161–171

    Article  CAS  PubMed  Google Scholar 

  • Li WR, **e XB, Shi QS, Duan SS, Ouyang YS, Chen YB (2011b) Antibacterial effect of silver nanoparticles on Staphylococcus aureus. Biometals 24:135–141

    Article  CAS  PubMed  Google Scholar 

  • Lohiya NK, Balasubramanian K, Ansari AS (2016) Indian folklore medicine in managing men’s health and wellness. Andrologia 48:894–907

    Article  CAS  PubMed  Google Scholar 

  • Maensiri S, Laokul P, Klinkaewnarong J, Phokha S, Promarak V, Seraphin S (2008) Indium oxide (In2O3) nanoparticles using Aloe vera plant extract: synthesis and optical properties. J Optoelectron Adv Mater 10:161–165

    Google Scholar 

  • Malik P, Shankar R, Malik V, Sharma N, Mukherjee TK (2014) Green chemistry based benign routes for nanoparticle synthesis. J Nanoparticles 2014:14

    Article  CAS  Google Scholar 

  • Malviya N, Malviya S, Jain S, Vyas S (2016) A review of the potential of medicinal plants in the management and treatment of male sexual dysfunction. Andrologia 48:880–893

    Article  CAS  PubMed  Google Scholar 

  • Mansouri E, Keshtkar A, Khaki AA, Khaki A (2016) Antioxidant effects of Allium cepa and cinnamon on sex hormones and serum antioxidant capacity in female rats exposed to power frequency electric and magnetic fields. Int J Womens Health Reprod Sci 4:141–145

    Article  CAS  Google Scholar 

  • Marshall AT, Haverkamp RG, Davies CE, Parsons JG, Gardea-Torresdey JL, van Agterveld D (2007) Accumulation of gold nanoparticles in Brassica juncea. Int J Phytoremediation 9:197–206

    Article  CAS  PubMed  Google Scholar 

  • Maurya R, Singh G, Murthy PS, Mehrotra S, Singh D, Bhargava B (2007) Pharmaceutical composition containing butea isoflavones for the prevention/treatment of bone disorders and a process for the preparation thereof. WO Patent 2007099432

    Google Scholar 

  • Mitra SK, Rangesh PR (2004a) Hyperacidity (Amlapitta). In: Mishra LC (ed) Scientific basis for ayurvedic therapies. CRC Press, New York, NY, pp 340–353

    Google Scholar 

  • Mitra SK, Rangesh PR (2004b) Irritable colon (Grahani). In: Mishra LC (ed) Scientific basis for ayurvedic therapies. CRC Press, New York, NY, pp 356–368

    Google Scholar 

  • Mittal AK, Chisti Y, Banerjee UC (2013) Synthesis of metallic nanoparticles using plants. Biotechnol Adv 31:346–356

    Article  CAS  PubMed  Google Scholar 

  • Mondal S, Roy N, Laskar RA, Sk I, Basu S, Mandal D, Begum NA (2011) Biogenic synthesis of Ag, Au and bimetallic Au/Ag alloy nanoparticles using aqueous extract of mahogany (Swietenia mahagoni JACQ.) leaves. Colloids Surf B: Biointerfaces 82:497–504

    Article  CAS  PubMed  Google Scholar 

  • Mousa SA, Qari MH, Ardawi MS (2013) Compositions and methods of natural products in nanoformulations for the prevention and treatment of osteoporosis. US Patent 8,563,053

    Google Scholar 

  • MubarakAli D, Thajuddin N, Jeganathan K, Gunasekaran M (2011) Plant extract mediated synthesis of silver and gold nanoparticles and its antibacterial activity against clinically isolated pathogens. Colloids Surf B: Biointerfaces 85:360–365

    Article  CAS  PubMed  Google Scholar 

  • Mukherjee PK, Venkatesh M, Kumar V (2007) An overview on the development in regulation and control of medicinal and aromatic plants in the Indian system of medicine. Bol Latinoam Caribe Plant Med Aromát 6:129–137

    Google Scholar 

  • Mukundan D, Mohankumar R, Vasanthakumari R (2015) Green synthesis of silver nanoparticles using leaves extract of Bauhinia tomentosa Linn and its in vitro anticancer potential. Mater Today Proc 2:4309–4316

    Google Scholar 

  • Nagati VB, Alwala J, Koyyati R, Donda MR, Banala R, Padigya PR (2012) Green synthesis of plant-mediated silver nanoparticles using Withania somnifera leaf extract and evaluation of their antimicrobial activity. Asian Pac J Trop Biomed 2:1–5

    Google Scholar 

  • Nair AM, Saraf MN (1995) Inhibition of antigen and compound 48/80 induced contractions of guinea pig trachea by the ethanolic extract of the leaves of Vitex negundo Linn. Indian J Pharmacol 27:230

    Google Scholar 

  • Narasimhan S, Anitha G, Illango K, Mohan KR (2006) Bio-assay guided isolation of active principles from medicinally important plants. In: Sharma RK, Arora R (eds) Herbal drugs: a twenty first century perspective. JAYPEE Brothers, New Delhi, pp 70–76

    Google Scholar 

  • Nayak AP, Tiyaboonchai W, Patankar S, Madhusudhan B, Souto EB (2010) Curcuminoids-loaded lipid nanoparticles: novel approach towards malaria treatment. Colloids Surf B: Biointerfaces 81:263–273

    Article  CAS  PubMed  Google Scholar 

  • Nikalje AP (2015) Nanotechnology and its applications in medicine. Med Chem 5:81–89

    Article  CAS  Google Scholar 

  • Niraimathi KL, Sudha V, Lavanya R, Brindha P (2013) Biosynthesis of silver nanoparticles using Alternanthera sessilis (Linn.) extract and their antimicrobial, antioxidant activities. Colloids Surf B: Biointerfaces 102:288–291

    Article  CAS  PubMed  Google Scholar 

  • Njagi EC, Huang H, Stafford L, Genuino H, Galindo HM, Collins JB, Hoag GE, Suib SL (2010) Biosynthesis of iron and silver nanoparticles at room temperature using aqueous sorghum bran extracts. Langmuir 27:264–271

    Article  PubMed  CAS  Google Scholar 

  • Noruzi M, Zare D, Khoshnevisan K, Davoodi D (2011) Rapid green synthesis of gold nanoparticles using Rosa hybrida petal extract at room temperature. Spectrochim Acta A Mol Biomol Spectrosc 79:1461–1465

    Article  CAS  PubMed  Google Scholar 

  • Oliveira MM, Ugarte D, Zanchet D, Zarbin AJ (2005) Influence of synthetic parameters on the size, structure, and stability of dodecanethiol-stabilized silver nanoparticles. J Colloid Interface Sci 292:429–435

    Article  CAS  PubMed  Google Scholar 

  • Padil VV, Černík M (2013) Green synthesis of copper oxide nanoparticles using gum karaya as a biotemplate and their antibacterial application. Int J Nanomedicine 8:889

    PubMed Central  Google Scholar 

  • Pan SY, Litscher G, Gao SH, Zhou SF, Yu ZL, Chen HQ, Zhang SF, Tang MK, Sun JN, Ko KM (2014) Historical perspective of traditional indigenous medical practices: the current renaissance and conservation of herbal resources. Evid Based Complement Alternat Med 2014:525340

    PubMed  PubMed Central  Google Scholar 

  • Pandey MM, Rastogi S, Rawat AK (2013) Indian traditional ayurvedic system of medicine and nutritional supplementation. Evid Based Complement Alternat Med 376327:1–12

    Google Scholar 

  • Panigrahi S, Praharaj S, Basu S, Ghosh SK, Jana S, Pande S, Vo-Dinh T, Jiang H, Pal T (2006) Self-assembly of silver nanoparticles: synthesis, stabilization, optical properties, and application in surface-enhanced Raman scattering. J Phys Chem B 110:13436–13444

    Article  CAS  PubMed  Google Scholar 

  • Pankhurst QA, Connolly J, Jones SK, Dobson JJ (2003) Applications of magnetic nanoparticles in biomedicine. J Phys D Appl Phys 36:R167

    Article  CAS  Google Scholar 

  • Pileni MP (1997) Nanosized particles made in colloidal assemblies. Langmuir 13:3266–3276

    Article  CAS  Google Scholar 

  • Pollini M, Paladini F, Catalano M, Taurino A, Licciulli A, Maffezzoli A, Sannino A (2011) Antibacterial coatings on haemodialysis catheters by photochemical deposition of silver nanoparticles. J Mater Sci Mater Med 22:2005–2012

    Article  CAS  PubMed  Google Scholar 

  • Prabakar K, Sivalingam P, Rabeek SI, Muthuselvam M, Devarajan N, Arjunan A, Karthick R, Suresh MM, Wembonyama JP (2013) Evaluation of antibacterial efficacy of phyto fabricated silver nanoparticles using Mukia scabrella (Musumusukkai) against drug resistance nosocomial Gram negative bacterial pathogens. Colloids Surf B: Biointerfaces 104:282–288

    Article  CAS  PubMed  Google Scholar 

  • Prasad R (2014) Synthesis of silver nanoparticles in photosynthetic plants. Journal of Nanoparticles, Article ID 963961, https://doi.org/10.1155/2014/963961

  • Prasad R, Jha A, Prasad K (2018) Exploring the realms of nature for nanosynthesis. Springer International Publishing (ISBN 978-3-319-99570-0) https://www.springer.com/978-3-319-99570-0

  • Prasad KS, Patel H, Patel T, Patel K, Selvaraj K (2013) Biosynthesis of Se nanoparticles and its effect on UV-induced DNA damage. Colloids Surf B: Biointerfaces 103:261–266

    Article  CAS  PubMed  Google Scholar 

  • Prasad R, Pandey R, Barman I (2016) Engineering tailored nanoparticles with microbes: quo vadis. WIREs Nanomed Nanobiotechnol 8:316–330. https://doi.org/10.1002/wnan.1363

  • Prasad R, Pandey R, Varma A, Barman I (2017) Polymer based nanoparticles for drug delivery systems and cancer therapeutics. In: Kharkwal H, Janaswamy S (eds) Natural polymers for drug delivery. CAB International, UK, pp 53–70

    Google Scholar 

  • Puvanakrishnan P, Park J, Chatterjee D, Krishnan S, Tunnell JW (2012) In vivo tumor targeting of gold nanoparticles: effect of particle type and dosing strategy. Int J Nanomedicine 7:1251

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Qu J, Luo C, Cong Q, Yuan X (2012) A new insight into the recycling of hyperaccumulator: synthesis of the mixed Cu and Zn oxide nanoparticles using Brassica juncea L. Int J Phytoremediation 14:854–860

    Article  CAS  PubMed  Google Scholar 

  • Rajiv P, Rajeshwari S, Venckatesh R (2013) Bio-fabrication of zinc oxide nanoparticles using leaf extract of Parthenium hysterophorus L. and its size-dependent antifungal activity against plant fungal pathogens. Spectrochim Acta A Mol Biomol Spectrosc 112:384–387

    Article  CAS  PubMed  Google Scholar 

  • Ramanathan R, Field MR, O’Mullane AP, Smooker PM, Bhargava SK, Bansal V (2013) Aqueous phase synthesis of copper nanoparticles: a link between heavy metal resistance and nanoparticle synthesis ability in bacterial systems. Nanoscale 5:2300–2306

    Article  CAS  PubMed  Google Scholar 

  • Ravishankar B, Shukla VJ (2007) Indian systems of medicine: a brief profile. Afr J Tradit Complement Altern Med 4:319–337

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Samaligy MS, Afifi NN, Mahmoud EA (2006) Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance. Int J Pharm 319:121–129

    Article  PubMed  CAS  Google Scholar 

  • Sandhya S, Sushil K (1998) Withania somnifera: the Indian ginseng ashwagandha. Central Institute of Medicinal and Aromatic Plants, Lucknow, pp 1–293

    Google Scholar 

  • Sandhya T, Lathika KM, Pandey BN, Mishra KP (2006) Potential of traditional ayurvedic formulation, Triphala, as a novel anticancer drug. Cancer Lett 231:206–214

    Article  CAS  PubMed  Google Scholar 

  • Sangeeta D, Sidhu H, Thind SK, Nath R, Vaidyanathan S (1993) Therapeutic response of Tribulus terrestris (gokhru) aqueous extract on hyperoxaluria in male adult rats. Phytother Res 7:116–119

    Article  Google Scholar 

  • Sankar R, Manikandan P, Malarvizhi V, Fathima T, Shivashangari KS, Ravikumar V (2014) Green synthesis of colloidal copper oxide nanoparticles using Carica papaya and its application in photocatalytic dye degradation. Spectrochim Acta A Mol Biomol Spectrosc 121:746–750

    Article  CAS  PubMed  Google Scholar 

  • Sankaranarayanan AS (1988) Folk-lore medicines for jaundice from Coimbatore and Palghat districts of Tamil Nadu and Kerala, India. Anc Sci Life 7:175

    CAS  PubMed  PubMed Central  Google Scholar 

  • Sathishkumar M, Sneha K, Won SW, Cho CW, Kim S, Yun YS (2009) Cinnamon zeylanicum bark extract and powder mediated green synthesis of nano-crystalline silver particles and its bactericidal activity. Colloids Surf B: Biointerfaces 73:332–338

    Article  CAS  PubMed  Google Scholar 

  • Satyavani K, Gurudeeban S, Ramanathan T, Balasubramanian T (2011) Biomedical potential of silver nanoparticles synthesized from calli cells of Citrullus colocynthis (L.) Schrad. J Nanobiotechnol 9:43

    Article  CAS  Google Scholar 

  • Satyavati GV (1991) Guggulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Econ Med Plant Res 5:48–82

    Google Scholar 

  • Schaffazick SR, Guterres SS, Freitas LL, Pohlmann AR (2003) Caracterização e estabilidade físico-química de sistemas poliméricos nanoparticulados para administração de fármacos. Quím Nova São Paulo 26:726–737

    Article  CAS  Google Scholar 

  • Sen S, Chakraborty R, De B, Mazumder J (2009) Plants and phytochemicals for peptic ulcer: an overview. Pharmacogn Rev 3:270

    Google Scholar 

  • Sen S, Chakraborty R, De B, Ganesh T, Raghavendra HG, Debnath S (2010) Analgesic and anti-inflammatory herbs: a potential source of modern medicine. Int J Pharm Sci Res 1:32

    Google Scholar 

  • Shameli K, Bin Ahmad M, Jaffar Al-Mulla EA, Ibrahim NA, Shabanzadeh P, Rustaiyan A, Abdollahi Y, Bagheri S, Abdolmohammadi S, Usman MS, Zidan M (2012) Green biosynthesis of silver nanoparticles using Callicarpa maingayi stem bark extraction. Molecules 17:8506–8517

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sharma PC, Yelne MB, Dennis TJ (2001) Jambu (Syzygium cumini). Database on Medicinal Plants used in Ayurveda Central Council for Research in Ayurveda and Siddha 3:314–331

    Google Scholar 

  • Sharma PC, Yelne MB, Dennis TJ (2002a) Langli (Gloriosa superba). Database on Medicinal Plants used in Ayurveda Central Council for Research in Ayurveda and Siddha 4:341–357

    Google Scholar 

  • Sharma PC, Yelne MB, Dennis TJ (eds) (2002b) Shunthi (Zingiber officinale Rosc). Database on Medicinal Plants used in Ayurveda Central Council for Research in Ayurveda and Siddha 5:315–390

    Google Scholar 

  • Sharma PC, Yelne MB, Dennis TJ (eds) (2002c) Manjishtha (Rubia cordifolia). Database on Medicinal Plants used in Ayurveda. Central Council for Research in Ayurveda and Siddha 5:171–186

    Google Scholar 

  • Sharma PC, Yelne MB, Dennis TJ (eds) (2002d) Lodhra (Symplocos racemosa). Database on Medicinal Plants used in Ayurveda. Central Council for Research in Ayurveda and Siddha 5:164–170

    Google Scholar 

  • Sharma N, Agarwal D, Gupta MK, Khinchi M (2011) A comprehensive review on floating drug delivery system. Int J Res Pharmaceut Biomed Sci 2:428–441

    Google Scholar 

  • Sharma VK, Siskova KM, Zboril R, Gardea-Torresdey JL (2014) Organic-coated silver nanoparticles in biological and environmental conditions: fate, stability and toxicity. Adv Colloid Interf Sci 204:15–34

    Article  CAS  Google Scholar 

  • Shen Y, Tang H, Van Kirk E, Murdoch W, Radosz M (2012) Curcumin-containing polymers and water-soluble curcumin derivatives as prodrugs of prodrug carriers. US Patent 13/119,454

    Google Scholar 

  • Shi F, Zhang Y, Yang G, Guo T, Feng N (2015) Preparation of a micro/nanotechnology based multi-unit drug delivery system for a Chinese medicine Niuhuang **ngxiao Wan and assessment of its antitumor efficacy. Int J Pharm 492:244–247

    Article  CAS  PubMed  Google Scholar 

  • Singh HK, Dhawan BN (1997) Neuropsychopharmacological effects of the ayurvedic nootropic Bacopa monniera Linn. (Brahmi). Indian J Pharmacol 29:359

    Google Scholar 

  • Singh S, Saikia JP, Buragohain AK (2013) A novel ‘green’ synthesis of colloidal silver nanoparticles (SNP) using Dillenia indica fruit extract. Colloids Surf B: Biointerfaces 102:83–85

    Google Scholar 

  • Song JY, Kim BS (2008) Biological synthesis of bimetallic Au/Ag nanoparticles using Persimmon (Diospyros kaki) leaf extract. Korean J Chem Eng 25:808–811

    Article  CAS  Google Scholar 

  • Sood S (1995) Identification of Priyangu through pharmaco-therapeutic studies with special reference to its Sonitasthapan activity. M.D. (Ayu) dissertation, Gujarat Ayurved University, Jamnagar, India

    Google Scholar 

  • Sperling RA, Gil PR, Zhang F, Zanella M, Parak WJ (2008) Biological applications of gold nanoparticles. Chem Soc Rev 37:1896–1908

    Article  CAS  PubMed  Google Scholar 

  • Suganya S, Senthil Ram T, Lakshmi BS, Giridev VR (2011) Herbal drug incorporated antibacterial nanofibrous mat fabricated by electrospinning: an excellent matrix for wound dressings. J Appl Polym Sci 121:2893–2899

    Article  CAS  Google Scholar 

  • Suguna L, Sivakumar P, Chandrakasan G (1996) Effects of Centella asiatica extract on dermal wound healing in rats. Indian J Exp Biol 34:1208–1211

    CAS  PubMed  Google Scholar 

  • Sukirtha R, Priyanka KM, Antony JJ, Kamalakkannan S, Thangam R, Gunasekaran P, Krishnan M, Achiraman S (2012) Cytotoxic effect of green synthesized silver nanoparticles using Melia azedarach against in vitro HeLa cell lines and lymphoma mice model. Process Biochem 47:273–279

    Article  CAS  Google Scholar 

  • Suman TY, Rajasree SR, Ramkumar R, Rajthilak C, Perumal P (2014) The green synthesis of gold nanoparticles using an aqueous root extract of Morinda citrifolia L. Spectrochim Acta A Mol Biomol Spectrosc 118:11–16

    Article  CAS  PubMed  Google Scholar 

  • Suriyakalaa U, Antony JJ, Suganya S, Siva D, Sukirtha R, Kamalakkannan S, Pichiah PT, Achiraman S (2013) Hepatocurative activity of biosynthesized silver nanoparticles fabricated using Andrographis paniculata. Colloids Surf B: Biointerfaces 102:189–194

    Article  CAS  PubMed  Google Scholar 

  • Sýkora D, Kašička V, Mikšík I, Řezanka P, Záruba K, Matějka P, Král V (2010) Application of gold nanoparticles in separation sciences. J Sep Sci 33:372–387

    Article  PubMed  CAS  Google Scholar 

  • Tadic M, Kralj S, Jagodic M, Hanzel D, Makovec D (2014) Magnetic properties of novel superparamagnetic iron oxide nanoclusters and their peculiarity under annealing treatment. Appl Surf Sci 322:255–264

    Article  CAS  Google Scholar 

  • Tambi MI, Imran MK, Henkel RR (2012) Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism. Andrologia 44:226–230

    Article  PubMed  CAS  Google Scholar 

  • Thakkar KN, Mhatre SS, Parikh RY (2010) Biological synthesis of metallic nanoparticles. Nanomedicine 6:257–262

    Article  CAS  PubMed  Google Scholar 

  • Thatte UM, Rao SG, Dahanukar SA (1994) Tinospora cordifolia induces colony stimulating activity in serum. J Postgrad Med 40:202

    CAS  PubMed  Google Scholar 

  • Torres-Chavolla E, Ranasinghe RJ, Alocilja EC (2010) Characterization and functionalization of biogenic gold nanoparticles for biosensing enhancement. IEEE Trans Nanotechnol 9:533–538

    Article  Google Scholar 

  • Tripathi RM, Gupta SS, Chandra D (1973) Anti-trypsin and antihyaluronidase activity of volatile oil of Curcuma longa (Haldi). Indian J Pharmacol 5:260

    Google Scholar 

  • Tripathy A, Raichur AM, Chandrasekaran N, Prathna TC, Mukherjee A (2010) Process variables in biomimetic synthesis of silver nanoparticles by aqueous extract of Azadirachta indica (Neem) leaves. J Nanopart Res 12:237–246

    Article  CAS  Google Scholar 

  • Udupa KN, Prasad G (1964) Biomechanical and calcium-45 studies on the effect of Cissus quadrangularis in fracture repair. Indian J Med Res 52:480

    CAS  PubMed  Google Scholar 

  • Vanaja M, Rajeshkumar S, Paulkumar K, Gnanajobitha G, Malarkodi C, Annadurai G (2013) Phytosynthesis and characterization of silver nanoparticles using stem extract of Coleus aromaticus. Int J Mater Biomat Appl 3:1–4

    Google Scholar 

  • Vankar PS, Bajpai D (2010) Preparation of gold nanoparticles from Mirabilis jalapa flowers. Indian J Biochem Biophys 47(3):157–160

    CAS  PubMed  Google Scholar 

  • Velusamy P, Das J, Pachaiappan R, Vaseeharan B, Pandian K (2015) Greener approach for synthesis of antibacterial silver nanoparticles using aqueous solution of neem gum (Azadirachta indica L.). Ind Crop Prod 66:103–109

    Article  CAS  Google Scholar 

  • Vijayakumar M, Priya K, Nancy FT, Noorlidah A, Ahmed AB (2013) Biosynthesis, characterisation and anti-bacterial effect of plant-mediated silver nanoparticles using Artemisia nilagirica. Ind Crop Prod 41:235–240

    Article  CAS  Google Scholar 

  • Vyas DS, Sharma VN, Sharma HK, Khanna NK (1979) Preliminary study of antidiabetic properties of Aegle marmelos and Enicostemma littorale. Res Ind Med Yoga Homeo 14:63–65

    Google Scholar 

  • West PR, Ishii S, Naik GV, Emani NK, Shalaev VM, Boltasseva A (2010) Searching for better plasmonic materials. Laser Photon Res 4:795–808

    Article  CAS  Google Scholar 

  • Yadav D, Suri S, Choudhary AA, Sikender M, Hemant BN, Beg NM (2011) Novel approach: herbal remedies and natural products in pharmaceutical science as nano drug delivery systems. Int J Pharm Tech 3:3092–3116

    CAS  Google Scholar 

  • Yadav L, Tripathi RM, Prasad R, Pudake RN, Mittal J (2017) Antibacterial activity of Cu nanoparticles against E. coli, Staphylococcus aureus and Pseudomonas aeruginosa. Nano Biomed Eng. 9(1):9–14. https://doi.org/10.5101/nbe.v9i1. p9–14

  • Yao CH, Yeh JY, Chen YS, Li MH, Huang CH (2017) Wound-healing effect of electrospun gelatin nanofibres containing Centella asiatica extract in a rat model. J Tissue Eng Regen Med 11:905–915

    Article  CAS  PubMed  Google Scholar 

  • Yen FL, Wu TH, Lin LT, Cham TM, Lin CC (2008) Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats. Food Chem Toxicol 46:1771–1777

    Article  CAS  PubMed  Google Scholar 

  • Zahir AA, Rahuman AA (2012) Evaluation of different extracts and synthesised silver nanoparticles from leaves of Euphorbia prostrata against Haemaphysalis bispinosa and Hippobosca maculata. Vet Parasitol 187:511–520

    Article  PubMed  CAS  Google Scholar 

  • Zhao Y, Wang C, Chow AH, Ren K, Gong T, Zhang Z, Zheng Y (2010) Self-nanoemulsifying drug delivery system (SNEDDS) for oral delivery of Zedoary essential oil: formulation and bioavailability studies. Int J Pharm 383:170–177

    Article  CAS  PubMed  Google Scholar 

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  1. Centre for Applied Genetics, Department of Zoology, Bangalore University, Bengaluru, Karnataka, India

    Mahesh Pattabhiramaiah, Bhargavi Rajarathinam & Mallikarjuniah Shanthala

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  1. Mahesh Pattabhiramaiah
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  2. Bhargavi Rajarathinam
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  3. Mallikarjuniah Shanthala
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  1. Department of Botany, Karnatak University, Dharwad, Karnataka, India

    Devarajan Thangadurai

  2. Department of Environmental Science, Central University of Kerala, Kasaragod, Kerala, India

    Jeyabalan Sangeetha

  3. Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar, India

    Ram Prasad

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Pattabhiramaiah, M., Rajarathinam, B., Shanthala, M. (2020). Nanoparticles and Their Application in Folklore Medicine as Promising Biotherapeutics. In: Thangadurai, D., Sangeetha, J., Prasad, R. (eds) Functional Bionanomaterials. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-41464-1_4

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