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Pancreatic Surgery

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Enhanced Recovery After Surgery

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Abstract

Most generic enhanced recovery after surgery (ERAS) recommendations are also valid for pancreatic surgery. For issues specific for pancreatic resections, the literature suggests that routine preoperative biliary drainage should be avoided and patients should be allowed drinks and food at will from the first day after surgery. Furthermore, while perioperative prophylactic drainage cannot be routinely omitted, early drain removal in low-risk patients is safe. Minimally invasive techniques for distal pancreatectomy confer beneficial short-term outcomes, and there is no evidence that oncological outcomes are compromised. For pancreatoduodenectomies, the safety and potential benefits of minimally invasive surgery remain uncertain.

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References

  1. Fernandez-del Castillo C, Morales-Oyarvide V, McGrath D, Wargo JA, Ferrone CR, Thayer SP, et al. Evolution of the Whipple procedure at the Massachusetts General Hospital. Surgery. 2012;152(3 Suppl 1):S56–63.

    Article  PubMed  Google Scholar 

  2. McMillan MT, Malleo G, Bassi C, Allegrini V, Casetti L, Drebin JA, et al. Multicenter, prospective trial of selective drain management for pancreatoduodenectomy using risk stratification. Ann Surg. 2017;265(6):1209–18.

    Article  PubMed  Google Scholar 

  3. Lassen K, Nymo LS, Olsen F, Soereide K. Benchmarking of an aggregated length-of-stay after open and laparoscopic surgery for cancer of the digestive system. BJS Open. 2018;2(4):246–53.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Lassen K, Coolsen MM, Slim K, Carli F, de Aguilar-Nascimento JE, Schafer M, et al. Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. Clin Nutr. 2012;31(6):817–30.

    Article  PubMed  Google Scholar 

  5. Lassen K, Coolsen MM, Slim K, Carli F, de Aguilar-Nascimento JE, Schafer M, et al. Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. World J Surg. 2013;37(2):240–58.

    Article  PubMed  Google Scholar 

  6. Bond-Smith G, Belgaumkar AP, Davidson BR, Gurusamy KS. Enhanced recovery protocols for major upper gastrointestinal, liver and pancreatic surgery. Cochrane Database Syst Rev. 2016;2:Cd011382.

    PubMed  Google Scholar 

  7. Braga M, Pecorelli N, Ariotti R, Capretti G, Greco M, Balzano G, et al. Enhanced recovery after surgery pathway in patients undergoing pancreaticoduodenectomy. World J Surg. 2014;38(11):2960–6.

    Article  PubMed  Google Scholar 

  8. Coolsen MM, van Dam RM, Chigharoe A, Olde Damink SW, Dejong CH. Improving outcome after pancreaticoduodenectomy: experiences with implementing an enhanced recovery after surgery (ERAS) program. Dig Surg. 2014;31(3):177–84.

    Article  PubMed  Google Scholar 

  9. Coolsen MM, van Dam RM, van der Wilt AA, Slim K, Lassen K, Dejong CH. Systematic review and meta-analysis of enhanced recovery after pancreatic surgery with particular emphasis on pancreaticoduodenectomies. World J Surg. 2013;37(8):1909–18.

    Article  CAS  PubMed  Google Scholar 

  10. Lassen K, Høye A, Myrmel T. Randomised trials in surgery: the burden of evidence. Rev Recent Clin Trials. 2012;7:244–8.

    Article  PubMed  Google Scholar 

  11. Nicholson A, Lowe MC, Parker J, Lewis SR, Alderson P, Smith AF. Systematic review and meta-analysis of enhanced recovery programmes in surgical patients. Br J Surg. 2014;101(3):172–88.

    Article  CAS  PubMed  Google Scholar 

  12. Gillis C, Carli F. Promoting perioperative metabolic and nutritional care. Anesthesiology. 2015;123(6):1455–72.

    Article  CAS  PubMed  Google Scholar 

  13. Gustafsson UO, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J. Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg. 2011;146(5):571–7.

    Article  PubMed  Google Scholar 

  14. Aahlin EK, von Meyenfeldt M, Dejong CH, Ljungqvist O, Fearon KC, Lobo DN, et al. Functional recovery is considered the most important target: a survey of dedicated professionals. Perioper Med (Lond). 2014;3:5.

    Article  Google Scholar 

  15. Nymo LS, Søreide K, Kleive D, Olsen F, Lassen K. The effect of centralization on short term outcomes of pancreatoduodenectomy in a universal health care system. HPB (Oxford). 2019;21(3):319–27.

    Article  Google Scholar 

  16. Søreide K, Olsen F, Nymo LS, Kleive D, Lassen K. A nationwide cohort study of resection rates and short-term outcomes in open and laparoscopic distal pancreatectomy. HPB (Oxford). 2019;21(6):669–78.

    Article  Google Scholar 

  17. van Hilst J, de Rooij T, Klompmaker S, Rawashdeh M, Aleotti F, Al-Sarireh B, Alseidi A, Ateeb Z, Balzano G, Berrevoet F, Björnsson B. Minimally invasive versus open distal pancreatectomy for ductal adenocarcinoma (DIPLOMA): a pPan-European propensity score matched study. (1528–1140 (Electronic)). LID – https://doi.org/10.1097/SLA.0000000000002561.

  18. Esposito I, Kleeff J, Bergmann F, Reiser C, Herpel E, Friess H, et al. Most pancreatic cancer resections are R1 resections. Ann Surg Oncol. 2008;15(6):1651–60.

    Article  PubMed  Google Scholar 

  19. Verbeke CS. Resection margins in pancreatic cancer. Der Pathologe. 2013;34(Suppl 2):241–7.

    Article  PubMed  Google Scholar 

  20. Ethun CG, Kooby DA. The importance of surgical margins in pancreatic cancer. J Surg Oncol. 2016;113(3):283–8.

    Article  PubMed  Google Scholar 

  21. Studley H. Percentage of weight loss: a basic indicator of surgical risk in patients with chronic peptic ulcer. JAMA. 1936;106:458–60.

    Article  Google Scholar 

  22. Gilliland TM, Villafane-Ferriol N, Shah KP, Shah RM, Tran Cao HS, Massarweh NN, et al. Nutritional and metabolic derangements in pancreatic cancer and pancreatic resection. Nutrients. 2017;9(3):243.

    Article  CAS  PubMed Central  Google Scholar 

  23. Aahlin EK, Trano G, Johns N, Horn A, Soreide JA, Fearon KC, et al. Risk factors, complications and survival after upper abdominal surgery: a prospective cohort study. BMC Surg. 2015;15:83.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Weimann A, Braga M, Harsanyi L, Laviano A, Ljungqvist O, Soeters P, et al. ESPEN guidelines on enteral nutrition: surgery including organ transplantation. Clin Nutr. 2006;25(2):224–44.

    Article  CAS  PubMed  Google Scholar 

  25. Weimann A, Braga M, Carli F, Higashiguchi T, Hubner M, Klek S, et al. ESPEN guideline: clinical nutrition in surgery. Clin Nutr. 2017;36(3):623–50.

    Article  PubMed  Google Scholar 

  26. Olson SH, Xu Y, Herzog K, Saldia A, DeFilippis EM, Li P, et al. Weight loss, diabetes, fatigue, and depression preceding pancreatic cancer. Pancreas. 2016;45(7):986–91.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Probst P, Haller S, Bruckner T, Ulrich A, Strobel O, Hackert T, et al. Prospective trial to evaluate the prognostic value of different nutritional assessment scores in pancreatic surgery (NURIMAS pancreas). Br J Surg. 2017;104(8):1053–62.

    Article  CAS  PubMed  Google Scholar 

  28. Gianotti L, Besselink MG, Sandini M, Hackert T, Conlon K, Gerritsen A, et al. Nutritional support and therapy in pancreatic surgery: a position paper of the International Study Group on Pancreatic Surgery (ISGPS). Surgery. 2018;164(5):1035–48.

    Article  PubMed  Google Scholar 

  29. Sultan J, Griffin SM, Di FF, Kirby JA, Shenton BK, Seal CJ, et al. Randomized clinical trial of omega-3 fatty acid-supplemented enteral nutrition versus standard enteral nutrition in patients undergoing oesophagogastric cancer surgery. Br J Surg. 2012;99(3):346–55.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Hubner M, Cerantola Y, Grass F, Bertrand PC, Schafer M, Demartines N. Preoperative immunonutrition in patients at nutritional risk: results of a double-blinded randomized clinical trial. Eur J Clin Nutr. 2012;66(7):850–5.

    Article  CAS  PubMed  Google Scholar 

  31. Hegazi RA, Hustead DS, Evans DC. Preoperative standard oral nutrition supplements vs immunonutrition: results of a systematic review and meta-analysis. J Am Coll Surg. 2014;219(5):1078–87.

    Article  PubMed  Google Scholar 

  32. Probst P, Ohmann S, Klaiber U, Huttner FJ, Billeter AT, Ulrich A, et al. Meta-analysis of immunonutrition in major abdominal surgery. Br J Surg. 2017;104(12):1594–608.

    Article  CAS  PubMed  Google Scholar 

  33. Pavlidis ET, Pavlidis TE. Pathophysiological consequences of obstructive jaundice and perioperative management. Hepatobiliary Pancreat Dis Int. 2018;17(1):17–21.

    Article  PubMed  Google Scholar 

  34. Johnson RC, Ahrendt SA. The case against preoperative biliary drainage with pancreatic resection. HPB (Oxford). 2006;8(6):426–31.

    Article  Google Scholar 

  35. Scheufele F, Aichinger L, Jager C, Demir IE, Schorn S, Sargut M, et al. Effect of preoperative biliary drainage on bacterial flora in bile of patients with periampullary cancer. Br J Surg. 2017;104(2):e182–e8.

    Article  CAS  PubMed  Google Scholar 

  36. Ng ZQ, Suthananthan AE, Rao S. Effect of preoperative biliary stenting on post-operative infectious complications in pancreaticoduodenectomy. Ann Hepatobiliary Pancreat Surg. 2017;21(4):212–6.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Chen Y, Ou G, Lian G, Luo H, Huang K, Huang Y. Effect of preoperative biliary drainage on complications following pancreatoduodenectomy: a meta-analysis. Medicine (Baltimore). 2015;94(29):e1199.

    Article  Google Scholar 

  38. van der Gaag NA. Preoperative biliary drainage for cancer of the head of the pancreas. N Engl J Med. 2010;362(2):129–37.

    Article  PubMed  Google Scholar 

  39. Cazauran JB, Perinel J, Kepenekian V, El Bechwaty M, Nappo G, Pioche M, et al. Unnecessary preoperative biliary drainage: impact on perioperative outcomes of resectable periampullary tumors. Langenbecks Arch Surg. 2017;402(8):1187–96.

    Article  PubMed  Google Scholar 

  40. Lee PJ, Podugu A, Wu D, Lee AC, Stevens T, Windsor JA. Preoperative biliary drainage in resectable pancreatic cancer: a systematic review and network meta-analysis. HPB. 2018;20(6):477–86.. (1477–2574 (Electronic)).

    Article  PubMed  Google Scholar 

  41. Shaib Y, Rahal MA, Rammal MO, Mailhac A, Tamim H. Preoperative biliary drainage for malignant biliary obstruction: results from a national database. J Hepatobiliary Pancreat Sci. 2017;24(11):637–42.. (1868–6982 (Electronic)).

    Article  PubMed  Google Scholar 

  42. Saxena P, Kumbhari V, Zein ME, Khashab MA. Preoperative biliary drainage. Dig Endosc. 2015;27(2):265–77.

    Article  PubMed  Google Scholar 

  43. Dorcaratto D, Hogan NM, Munoz E, Garces M, Limongelli P, Sabater L, et al. Is percutaneous transhepatic biliary drainage better than endoscopic drainage in the management of jaundiced patients awaiting pancreaticoduodenectomy? A systematic review and meta-analysis. J Vasc Interv Radiol. 2018;29(5):676–87. (1535–7732 (Electronic)).

    Article  PubMed  Google Scholar 

  44. Crippa S, Cirocchi R, Partelli S, Petrone MC, Muffatti F, Renzi C, et al. Systematic review and meta-analysis of metal versus plastic stents for preoperative biliary drainage in resectable periampullary or pancreatic head tumors. Eur J Surg Oncol. 2016;42(9):1278–85.

    Article  CAS  PubMed  Google Scholar 

  45. Tol JA, van Hooft JE, Timmer R, Kubben FJ, van der Harst E, de Hingh IH, et al. Metal or plastic stents for preoperative biliary drainage in resectable pancreatic cancer. Gut. 2016;65(12):1981–7.

    Article  CAS  PubMed  Google Scholar 

  46. Olsson G, Frozanpor F, Lundell L, Enochsson L, Ansorge C, Del Chiaro M, et al. Preoperative biliary drainage by plastic or self-expandable metal stents in patients with periampullary tumors: results of a randomized clinical study. Endosc Int Open. 2017;5(9):E798–808.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Ballard DD, Rahman S, Ginnebaugh B, Khan A, Dua KS. Safety and efficacy of self-expanding metal stents for biliary drainage in patients receiving neoadjuvant therapy for pancreatic cancer. Endosc Int Open. 2018;6(6):E714–E21.

    Article  PubMed  PubMed Central  Google Scholar 

  48. van Hilst J, de Rooij T, Abu Hilal M, Asbun HJ, Barkun J, Boggi U, et al. Worldwide survey on opinions and use of minimally invasive pancreatic resection. HPB (Oxford). 2017;19(3):190–204.

    Article  Google Scholar 

  49. Klompmaker S, van Zoggel DM, Watkins AA, Eskander MF, Tseng JF, Besselink MG, et al. Nationwide evaluation of patient selection for minimally invasive distal pancreatectomy using American College of Surgeons’ National Quality Improvement Program. Ann Surg. 2017;266(6):1055–61.

    Article  PubMed  Google Scholar 

  50. de Rooij T, van Hilst J, Vogel JA, van Santvoort HC, de Boer MT, Boerma D, et al. Minimally invasive versus open distal pancreatectomy (LEOPARD): study protocol for a randomized controlled trial. Trials. 2017;18(1):166. (1745–6215 (Electronic)).

    Article  PubMed  PubMed Central  Google Scholar 

  51. Plotkin A, Ceppa EP, Zarzaur BL, Kilbane EM, Riall TS, Pitt HA. Reduced morbidity with minimally invasive distal pancreatectomy for pancreatic adenocarcinoma. HPB (Oxford). 2017;19(3):279–85.

    Article  Google Scholar 

  52. Riviere D, Gurusamy KS, Kooby DA, Vollmer CM, Besselink MG, Davidson BR, et al. Laparoscopic versus open distal pancreatectomy for pancreatic cancer. Cochrane Database Syst Rev. 2016;4:CD011391.

    PubMed  Google Scholar 

  53. Rosok BI, de Rooij T, van Hilst J, Diener MK, Allen PJ, Vollmer CM, et al. Minimally invasive distal pancreatectomy. HPB (Oxford). 2017;19(3):205–14.

    Article  Google Scholar 

  54. de Rooij T, Jilesen AP, Boerma D, Bonsing BA, Bosscha K, van Dam RM, et al. A nationwide comparison of laparoscopic and open distal pancreatectomy for benign and malignant disease. J Am Coll Surg. 2015;220(3):263–70.. e1

    Article  PubMed  Google Scholar 

  55. Kendrick ML, Cusati D. Total laparoscopic pancreaticoduodenectomy: feasibility and outcome in an early experience. Arch Surg. 2010;145(1):19–23. (1538–3644 (Electronic)).

    Article  PubMed  Google Scholar 

  56. Palanivelu C, Rajan PS, Rangarajan M, Vaithiswaran V, Senthilnathan P, Parthasarathi R, Raj PP. Evolution in techniques of laparoscopic pancreaticoduodenectomy: a decade long experience from a tertiary center. J Hepatobiliary Pancreatic Surg. 2009;16(6):731. (1436–0691 (Electronic)).

    Article  CAS  Google Scholar 

  57. Palanivelu C, Senthilnathan P, Sabnis SC, Babu NS, Srivatsan Gurumurthy S, Anand Vijai N, et al. Randomized clinical trial of laparoscopic versus open pancreatoduodenectomy for periampullary tumours. Br J Surg. 2017;104(11):1443–50.

    Article  CAS  PubMed  Google Scholar 

  58. Adam MA, Choudhury K, Dinan MA. Minimally invasive versus open pancreaticoduodenectomy for cancer. Ann Surg. 2015;262(2):372–7.

    Article  PubMed  Google Scholar 

  59. Adam MA, Thomas S, Youngwirth L, Pappas T, Roman SA, Sosa JA. Defining a hospital volume threshold for minimally invasive pancreaticoduodenectomy in the United States. JAMA Surg. 2017;152(4):336–42.

    Article  PubMed  PubMed Central  Google Scholar 

  60. Klompmaker S, van Hilst J, Wellner UF, Busch OR, Coratti A, D’Hondt M, et al. Outcomes after minimally-invasive versus open pancreatoduodenectomy: a pan-European propensity score matched study. Ann Surg 2018. https://doi.org/10.1097/SLA.0000000000002850.

  61. Chapman BC, Gajdos C, Hosokawa P, Henderson W, Paniccia A, Overbey DM, et al. Comparison of laparoscopic to open pancreaticoduodenectomy in elderly patients with pancreatic adenocarcinoma. Surg Endosc. 2018;32(5):2239–48.

    Article  PubMed  Google Scholar 

  62. Conrad C, Basso V, Passot G, Zorzi D, Li L, Chen HC, et al. Comparable long-term oncologic outcomes of laparoscopic versus open pancreaticoduodenectomy for adenocarcinoma: a propensity score weighting analysis. Surg Endosc. 2017;31(10):3970–8.

    Article  PubMed  Google Scholar 

  63. de Rooij T, Lu MZ, Steen MW, Gerhards MF, Dijkgraaf MG, Busch OR, et al. Minimally invasive versus open pancreatoduodenectomy: systematic review and meta-analysis of comparative cohort and registry studies. Ann Surg. 2016;264(2):257–67.

    Article  PubMed  Google Scholar 

  64. Kantor O, Talamonti MS, Sharpe S, Lutfi W, Winchester DJ, Roggin KK, et al. Laparoscopic pancreaticoduodenectomy for adenocarcinoma provides short-term oncologic outcomes and long-term overall survival rates similar to those for open pancreaticoduodenectomy. Am J Surg. 2017;213(3):512–5.

    Article  PubMed  Google Scholar 

  65. Kendrick ML, van Hilst J, Boggi U, de Rooij T, Walsh RM, Zeh HJ, et al. Minimally invasive pancreatoduodenectomy. HPB (Oxford). 2017;19(3):215–24.

    Article  Google Scholar 

  66. Torphy RJ, Friedman C, Halpern A, Chapman BC, Ahrendt SS, McCarter MM, et al. Comparing short-term and oncologic outcomes of minimally invasive versus open pancreaticoduodenectomy across low and high volume centers. Ann Surg. 2018. https://doi.org/10.1097/SLA.0000000000002810.

  67. van Hilst J, de Rooij T, Basscha K. Laparoscopic versus open pancreatoduodenectomy (LEOPARD-2): a multicenter patient-blinded, randomized controlled trial. Pancreatology. 2018;(4, supplement (free papers)):2.

    Google Scholar 

  68. Witzigmann H, Diener MK, Kienkotter S, Rossion I, Bruckner T, Barbel W, et al. No need for routine drainage after pancreatic head resection: the dual-Center, randomized, controlled PANDRA trial (ISRCTN04937707). Ann Surg. 2016;264(3):528–37.

    Article  PubMed  Google Scholar 

  69. Van Buren G 2nd, Bloomston M, Hughes SJ, Winter J, Behrman SW, Zyromski NJ, et al. A randomized prospective multicenter trial of pancreaticoduodenectomy with and without routine intraperitoneal drainage. Ann Surg. 2014;259(4):605–12.

    Article  PubMed  Google Scholar 

  70. Callery MP, Pratt WB, Kent TS, Chaikof EL, Vollmer CM Jr. A prospectively validated clinical risk score accurately predicts pancreatic fistula after pancreatoduodenectomy. J Am Coll Surg. 2013;216(1):1–4. (1879–1190 (Electronic)).

    Article  PubMed  Google Scholar 

  71. Correa-Gallego C, Brennan MF, D’Angelica M, Fong Y, Dematteo RP, Kingham TP, et al. Operative drainage following pancreatic resection: analysis of 1122 patients resected over 5 years at a single institution. Ann Surg. 2013;258(6):1051–8.

    Article  PubMed  Google Scholar 

  72. Adham M, Chopin-Laly X, Lepilliez V, Gincul R, Valette PJ, Ponchon T. Pancreatic resection: drain or no drain? Surgery. 2013;154(5):1069–77.

    Article  PubMed  Google Scholar 

  73. Cecka F, Lovecek M, Jon B, Skalicky P, Subrt Z, Neoral C, et al. Intra-abdominal drainage following pancreatic resection: a systematic review. World J Gastroenterol. 2015;21(40):11458–68.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  74. Huttner FJ, Probst P, Knebel P, Strobel O, Hackert T, Ulrich A, et al. Meta-analysis of prophylactic abdominal drainage in pancreatic surgery. Br J Surg. 2017;104(6):660–8.

    Article  CAS  PubMed  Google Scholar 

  75. Kaminsky PM, Mezhir JJ. Intraperitoneal drainage after pancreatic resection: a review of the evidence. J Surg Res. 2013;184(2):925–30.

    Article  PubMed  Google Scholar 

  76. Schorn S, Nitsche U, Demir IE, Scheufele F, Tieftrunk E, Schirren R, et al. The impact of surgically placed, intraperitoneal drainage on morbidity and mortality after pancreas resection- A systematic review & meta-analysis. Pancreatolog. 2018;18(3):334–45.

    Article  Google Scholar 

  77. Wang Q, Jiang YJ, Li J, Yang F, Di Y, Yao L, et al. Is routine drainage necessary after pancreaticoduodenectomy? World J Gastroenterol. 2014;20(25):8110–8.

    Article  PubMed  PubMed Central  Google Scholar 

  78. Yamashita S, Ishizawa T, Ichida A, Kaneko J, Aoki T, Sakamoto Y, et al. Advantages and disadvantages of prophylactic abdominal drainage in distal pancreatectomy. World J Surg. 2016;40(5):1226–35.

    Article  PubMed  Google Scholar 

  79. Bassi C, Molinari E, Malleo G, Crippa S, Butturini G, Salvia R, et al. Early versus late drain removal after standard pancreatic resections: results of a prospective randomized trial. Ann Surg. 2010;252(2):207–14.

    Article  PubMed  Google Scholar 

  80. McMillan MT, Malleo G, Bassi C, Butturini G, Salvia R, Roses RE, et al. Drain management after pancreatoduodenectomy: reappraisal of a prospective randomized trial using risk stratification. J Am Coll Surg. 2015;221(4):798–809.

    Article  PubMed  Google Scholar 

  81. Akizuki E, Kimura Y, Nobuoka T, Imamura M, Nagayama M, Sonoda T, et al. Reconsideration of postoperative oral intake tolerance after pancreaticoduodenectomy: prospective consecutive analysis of delayed gastric emptying according to the ISGPS definition and the amount of dietary intake. Ann Surg. 2009;249(6):986–94.

    Article  PubMed  Google Scholar 

  82. Wente MN, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, Izbicki JR, et al. Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 2007;142(5):761–8.

    Article  PubMed  Google Scholar 

  83. Gerritsen A, Besselink MG, Gouma DJ, Steenhagen E, Borel Rinkes IH, Molenaar IQ. Systematic review of five feeding routes after pancreatoduodenectomy. Br J Surg. 2013;100(5):589–98.

    Article  CAS  PubMed  Google Scholar 

  84. Gerritsen A, Wennink RA, Besselink MG, van Santvoort HC, Tseng DS, Steenhagen E, et al. Early oral feeding after pancreatoduodenectomy enhances recovery without increasing morbidity. HPB (Oxford). 2014;16(7):656–64.

    Article  Google Scholar 

  85. Kleive D, Sahakyan MA, Labori KJ, Lassen K. Nasogastric tube on demand is rarely necessary after pancreatoduodenectomy within an enhanced recovery pathway. World J Surg. 2019;43(10):2616–22.

    Article  CAS  PubMed  Google Scholar 

  86. Lewis SJ, Egger M, Sylvester PA, Thomas S. Early enteral feeding versus “nil by mouth” after gastrointestinal surgery: systematic review and meta-analysis of controlled trials. BMJ. 2001;323(7316):773–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  87. Lassen K. Systematic review of five feeding routes after pancreatoduodenectomy. (Br J Surg 2013; 100: 589–-598). Br J Surg. 2013;100(5):599.

    Article  CAS  PubMed  Google Scholar 

  88. Tanaka M, Heckler M, Mihaljevic AL, Probst P, Klaiber U, Heger U, et al. Meta-analysis of effect of routine enteral nutrition on postoperative outcomes after pancreatoduodenectomy. Br J Surg. 2019;106(9):1138–46.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Gastrointestinal Surgery, University Hospital of North Norway, Institute of Clinical Medicine, The Arctic University of Norway, Tromsø, Norway

    Linn S. Nymo

  2. Department of Gastrointestinal Surgery, University Hospital of North Norway, Institute of Clinical Medicine, The Arctic University of Norway, Tromsø, Norway

    Kristoffer Lassen

  3. Department of Hepatobiliary and Pancreatic Surgery, Oslo University Hospital, Oslo, Norway

    Kristoffer Lassen

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  1. Linn S. Nymo
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  1. Department of Surgery, Örebro University Hospital, Örebro, Sweden

    Olle Ljungqvist

  2. Yeovil District Hospital NHS Foundation Trust Higher Kingston, Yeovil, Somerset, UK

    Nader K. Francis

  3. Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s, Hospital Harvard Medical School, Boston, MA, USA

    Richard D. Urman

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Nymo, L.S., Lassen, K. (2020). Pancreatic Surgery. In: Ljungqvist, O., Francis, N., Urman, R. (eds) Enhanced Recovery After Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-33443-7_57

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