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Dietary Phytochemicals and Their Potential Effects on Diabetes Mellitus 2

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Plant and Human Health, Volume 3

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Abstract

Type 2 diabetes mellitus (T2DM) is one of the most important contemporary medical problems that exceed 200 million worldwide. T2DM causes increased risks of cardiovascular disease, kidney failure, blindness, neuropathy, and peripheral circulatory disease. In this chapter; we discuss dietary phytochemicals, and their different species commonly used in dietary fibers and that have shown experimental or clinical antidiabetic activity in all over word. The dietary phytochemicals which are most effective and the most commonly studied in relation to T2DM are polyphenols (simple phenolic acids, anthocyanins, cyanidin, flavonoids, ferulic acid, resveratrol, chalcones, lignans, curcumin, luteolin); flavonoid; isoflavonoids; saponins (ginsenoside, alloxan); amino acid (SACS, 4-hydroxyisoleucine, beta-pyrazol-1-ylalanine); terpenoids (geranylgeraniol, farnesol, geraniol terpenoids); glycosides (oleanolic acid, charantin); carotenoids (lycopene and b-carotene); phytosterols/stanols (phytic acid, a-galactosides, phenolics); linoleic acid; stevioside; oxyphytosterol; fagomine, dietary gallate; and ABA. All dietary phytochemicals have shown different types of mechanism of action and varying degrees of antidiabetic activity.

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Authors and Affiliations

  1. Siddhartha Institute of Pharmacy, Dehra Dun, Uttarakhand, India

    Rajbala Singh

  2. Glocal School of Pharmacy, Glocal University, Saharanpur, Uttar Pradesh, India

    Imran Kazmi

  3. Department of Pharmacology College of Pharmacy, Jouf University, Sakaka, Saudi Arabia

    Muhammad Afzal & Khalid Saad Alharbi

  4. College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

    Faisal Imam

Authors
  1. Rajbala Singh
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  2. Imran Kazmi
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  3. Muhammad Afzal
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  4. Faisal Imam
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  5. Khalid Saad Alharbi
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Editor information

Editors and Affiliations

  1. Vice President of the Islamic World Academy of Sciences, Amann, Jordan

    Munir Ozturk

  2. Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia

    Khalid Rehman Hakeem

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Singh, R., Kazmi, I., Afzal, M., Imam, F., Alharbi, K.S. (2019). Dietary Phytochemicals and Their Potential Effects on Diabetes Mellitus 2. In: Ozturk, M., Hakeem, K. (eds) Plant and Human Health, Volume 3. Springer, Cham. https://doi.org/10.1007/978-3-030-04408-4_4

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