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Pathology of Miscellaneous and Unusual Cancers of the Thyroid

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Thyroid Cancer

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Abstract

These rare neoplasms are solid masses, often less than 3 cm in diameter, and are well circumscribed (usually encapsulated). The cut surfaces are light colored, and vessels and small foci of fibrosis may be visible. Microscopically, the tumors consist of trabeculae and lobules of elongated, oval, or polygonal cells, usually medium sized and with poorly defined borders. The groups of cells are surrounded by capillaries and variable amounts of eosinophilic, hyalinized material, which consists of clumps of type IV collagen and laminin. The numerous cytoplasmic microfilaments (presumably keratin) present in many of the epithelial cells also contribute to the eosinophilic zones.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania Medical Center, 6 Founders Pavilion 3400 Spruce Street, Philadelphia, PA, 19104, USA

    Zubair W. Baloch MD, PhD & Virginia A. LiVolsi MD

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  1. Zubair W. Baloch MD, PhD
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  2. Virginia A. LiVolsi MD
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Correspondence to Zubair W. Baloch MD, PhD .

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Editors and Affiliations

  1. Department of Medicine, MedStar Washington Hospital Center Georgetown University School of Medicine, Washington, DC, USA

    Leonard Wartofsky

  2. Nuclear Medicine Research MedStar Research Institute and Washington Hospital Center, Georgetown University School of Medicine Washington Hospital Center, Washington, DC, USA

    Douglas Van Nostrand

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Baloch, Z.W., LiVolsi, V.A. (2016). Pathology of Miscellaneous and Unusual Cancers of the Thyroid. In: Wartofsky, L., Van Nostrand, D. (eds) Thyroid Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3314-3_82

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  • DOI: https://doi.org/10.1007/978-1-4939-3314-3_82

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