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Axon Regeneration: What Needs to Be Overcome?

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Axon Growth and Regeneration

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1162))

Abstract

Axon regeneration is crucial for recovery of function after nervous system injury. Over many years, research has uncovered numerous factors which prevent damaged axons from regrowing and reforming functional connections after damage. These factors are both extrinsic, relating to the central nervous system environment, and intrinsic, relating to the growth capacity of the neurons themselves. In this short review, I summarize these elements with a view to illustrating how they may be overcome to promote nervous system repair.

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  1. Department of Biochemistry and Molecular Biophysics, Columbia University, 701 W 168th Street, New York, NY, 10032, USA

    Andrew J. Murray

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    Andrew J. Murray

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Murray, A.J. (2014). Axon Regeneration: What Needs to Be Overcome?. In: Murray, A. (eds) Axon Growth and Regeneration. Methods in Molecular Biology, vol 1162. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-0777-9_1

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