Abstract
Percutaneous needle biopsy of musculoskeletal tumors is a safe and accurate technique, but it can be associated with a risk of malignant seeding of the biopsy tract, especially in patients with sarcomas. The biopsy tract is generally resected en bloc during definitive tumor surgery. Needle-tract seeding in uninvolved compartments or major neurovascular structures may necessitate more radical resection or preclude limb-sparing surgery. Hence, it is important to plan the needle path along the proposed surgical incision and to avoid traversing uninvolved compartments and major neurovascular structures. Interventional radiologists who perform needle biopsies of musculoskeletal tumors should have a thorough understanding of the cross-sectional compartmental anatomy and location of neurovascular structures in the upper and lower extremities. The radiologist should discuss the potential biopsy with the orthopedic surgeon who will be the primary operator for definitive resection.
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References
Bickels J, Jelinek JS, Shmookler BM, Neff RS, Malawer MM. Biopsy of musculoskeletal tumors. Current concepts. Clin Orthop Relat Res. 1999;368:212–19.
Jelinek JS, Murphey MD, Welker JA, et al. Diagnosis of primary bone tumors with image-guided percutaneous biopsy: experience with 110 tumors. Radiology. 2002;223:731–7.
Roberts CC, Liu PT, Wenger DE. Musculoskeletal tumor imaging, biopsy, and therapies: self-assessment module. AJR Am J Roentgenol. 2009;193(6 Suppl):S74–8.
Yao L, Nelson SD, Seeger LL, Eckardt JJ, Eilber FR. Primary musculoskeletal neoplasms: effectiveness of core-needle biopsy. Radiology. 1999;212:682–6.
Davies NM, Livesley PJ, Cannon SR. Recurrence of an osteosarcoma in a needle biopsy track. J Bone Joint Surg Br. 1993;75:977–8.
DiCaprio MR, Friedlaender GE. Malignant bone tumors: limb sparing versus amputation. J Am Acad Orthop Surg. 2003;11:25–37.
Anderson MW, Temple HT, Dussault RG, Kaplan PA. Compartmental anatomy: relevance to staging and biopsy of musculoskeletal tumors. AJR Am J Roentgenol. 1999;173:1663–71.
Bancroft LW, Peterson JJ, Kransdorf MJ, Berquist TH, O’Connor MI. Compartmental anatomy relevant to biopsy planning. Semin Musculoskelet Radiol. 2007;11:16–27.
Toomayan GA, Robertson F, Major NM, Brigman BE. Upper extremity compartmental anatomy: clinical relevance to radiologists. Skeletal Radiol. 2006;35:195–201.
Boles CA, Kannam S, Cardwell AB. The forearm: anatomy of muscle compartments and nerves. AJR Am J Roentgenol. 2000;174:151–9.
Toomayan GA, Robertson F, Major NM. Lower extremity compartmental anatomy: clinical relevance to radiologists. Skeletal Radiol. 2005;34:307–13.
Liu PT, Valadez SD, Chivers FS, Roberts CC, Beauchamp CP. Anatomically based guidelines for core needle biopsy of bone tumors: implications for limb-sparing surgery. Radiographics. 2007;27:189–205; discussion 6.
Welker JA, Henshaw RM, Jelinek J, Shmookler BM, Malawer MM. The percutaneous needle biopsy is safe and recommended in the diagnosis of musculoskeletal masses. Cancer. 2000;89:2677–86.
Mankin HJ, Lange TA, Spanier SS. The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. J Bone Joint Surg Am. 1982;64:1121–7.
Mankin HJ, Lange TA, Spanier SS. THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121–1127. Clin Orthop Relat Res. 2006;450:4–10.
Mankin HJ, Mankin CJ, Simon MA. The hazards of the biopsy, revisited. Members of the Musculoskeletal Tumor Society. J Bone Joint Surg Am. 1996;78:656–63.
Picci P, Sangiorgi L, Bahamonde L, et al. Risk factors for local recurrences after limb-salvage surgery for high-grade osteosarcoma of the extremities. Ann Oncol. 1997;8:899–903.
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Sendos, S.N., Gupta, S. (2014). Anatomic Guidelines and Approaches for Biopsy of the Long Bones. In: Ahrar, K., Gupta, S. (eds) Percutaneous Image-Guided Biopsy. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8217-8_23
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DOI: https://doi.org/10.1007/978-1-4614-8217-8_23
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