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XXX Syndrome

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Atlas of Genetic Diagnosis and Counseling

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Abstract

Females with a 47,XXX karyotype were first described by Jacobs (1979). The incidence of 47,XXX among female newborns is approximately 1 in 1,000 live births (Pennington et al. 1980). It is the most common female chromosomal abnormality. As some individuals are only mildly affected or asymptomatic, it is estimated that only 10 % of individuals with trisomy X are actually diagnosed (Tartaglia et al. 2010).

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Authors and Affiliations

  1. Medical Genetics, Shriners Hospitals for Children, Shreveport, LA, USA

    Harold Chen

  2. Perinatal and Clinical Genetics, Department of Pediatrics, LSU Health Sciences Center, 1501 Kings Highway, Shreveport, LA, 71130, USA

    Harold Chen

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  1. Harold Chen
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Correspondence to Harold Chen .

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Chen, H. (2016). XXX Syndrome. In: Atlas of Genetic Diagnosis and Counseling. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6430-3_251-2

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  • DOI: https://doi.org/10.1007/978-1-4614-6430-3_251-2

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-6430-3

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