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Methods for the Development of Recombinant Microorganisms for the Production of Natural Products

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Plant Metabolic Engineering

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2396))

Abstract

Metabolic engineering strives to develop microbial strains that are capable of producing a target chemical in a biological organism. There are still many challenges to overcome in order to achieve titers, yields, and productivities necessary for industrial production. The use of recombinant microorganisms to meet these needs is the next step for metabolic engineers. In this chapter, we aim to provide insight on both the applications of metabolic engineering for natural product biosynthesis as well as optimization methods.

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Acknowledgments

This work was supported by the NSF grant program grant number MCB-1817631 awarded to Mattheos Koffas.

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Authors and Affiliations

  1. Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY, USA

    Alexander Perl & Mattheos A. G. Koffas

  2. Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA

    Hunter Dalton, YeJong Yoo & Mattheos A. G. Koffas

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  1. Alexander Perl
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  2. Hunter Dalton
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  3. YeJong Yoo
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  4. Mattheos A. G. Koffas
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Corresponding author

Correspondence to Mattheos A. G. Koffas .

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Editors and Affiliations

  1. Department of Biological Sciences, University of North Texas, Denton, TX, USA

    Vladimir Shulaev

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Perl, A., Dalton, H., Yoo, Y., Koffas, M.A.G. (2022). Methods for the Development of Recombinant Microorganisms for the Production of Natural Products. In: Shulaev, V. (eds) Plant Metabolic Engineering. Methods in Molecular Biology, vol 2396. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1822-6_1

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  • DOI: https://doi.org/10.1007/978-1-0716-1822-6_1

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1821-9

  • Online ISBN: 978-1-0716-1822-6

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