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Screening screeners: calculating classification indices using correlations and cut-points
Given the recent push for universal screening, it is important to take into account how well a screener identifies children at risk for reading...
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Validation and optimal cut-off score of the World Health Organization Well-being Index (WHO-5) as a screening tool for depression among patients with schizophrenia
BackgroundThe utility of the World Health Organization Wellbeing Index (WHO-5) as rapid screening tool for depression has not yet been researched in...
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The optimal cut-off score of the Eating Attitude Test-26 for screening eating disorders in Japan
PurposeThe Eating Attitude Test-26 (EAT-26) is a screening tool for eating disorders (EDs) in clinical and non-clinical samples. The cut-off score...
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Calf circumference as a screening tool for low skeletal muscle mass: Cut-off values in independent Thai older adults
BackgroundCalf circumference is recommended as a marker for low muscle mass and as a case finding in the diagnosis of sarcopenia. However, the...
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Methods of determining optimal cut-point of diagnostic biomarkers with application of clinical data in ROC analysis: an update review
IntroductionAn important application of ROC analysis is the determination of the optimal cut-point for biomarkers in diagnostic studies. This...
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The phase angle cut-off point capable of discriminating hemodialysis patients with reduced exercise tolerance: a cross-sectional study
BackgroundPhase angle (PhA) is a prognostic marker of all-cause mortality in chronic kidney disease. However, no study has investigated this marker...
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Rapid screening of point mutations by mismatch amplification mutation assay PCR
AbstractMetabolic engineering frequently makes use of point mutation and saturation mutation library creation. At present, sequencing is the only...
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Utility and optimal cut-off point of the Somatic Symptom Scale-8 for central sensitization syndrome among outpatients with somatic symptoms and related disorders
BackgroundCentral sensitization syndrome (CSS) involves severe functional symptoms due to central sensitization. for patients with severe somatic...
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COVID-19 screening in low resource settings using artificial intelligence for chest radiographs and point-of-care blood tests
Artificial intelligence (AI) systems for detection of COVID-19 using chest X-Ray (CXR) imaging and point-of-care blood tests were applied to data...
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Smartphone-based point-of-care anemia screening in rural Bihar in India
BackgroundThe high prevalence of anemia in resource-constrained settings calls for easy-to-use, inexpensive screening tools. The Sanguina Smartphone...
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Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion
IntroductionWomen are on average diagnosed with diabetes mellitus at later age than men but have higher mortality. As the diagnosis of diabetes...
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An empirical comparison of statistical methods for multiple cut-off diagnostic test accuracy meta-analysis of the Edinburgh postnatal depression scale (EPDS) depression screening tool using published results vs individual participant data
BackgroundSelective reporting of results from only well-performing cut-offs leads to biased estimates of accuracy in primary studies of...
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What’s the cut-point?: a systematic investigation of tau PET thresholding methods
BackgroundTau positron emission tomography (PET) is increasing in popularity for biomarker characterization of Alzheimer’s disease (AD), and recent...
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A Systematic Review of Cost-Effectiveness Analyses of Colorectal Cancer Screening in Europe: Have Studies Included Optimal Screening Intensities?
ObjectiveTo assess the range of strategies analysed in European cost-effectiveness analyses (CEAs) of colorectal cancer (CRC) screening with respect...
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An Alternative Data Transformation Approach for ADA Cut Point Determination: Why Not Use a Weibull Transformation?
The testing of protein drug candidates for inducing the generation of anti-drug antibodies (ADA) plays a fundamental role in drug development. The...
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A robust pipeline for efficient knock-in of point mutations and epitope tags in zebrafish using fluorescent PCR based screening
BackgroundGenome editing using CRISPR/Cas9 has become a powerful tool in zebrafish to generate targeted gene knockouts models. However, its use for...
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Screening for Preeclampsia
Preeclampsia (PE) screening can be done at 11–13 + 6 weeks, along with combined aneuploidy screening. This offers an opportunity to identify women at...
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Bayesian Graded Response Models for Eating-Disorder Risk Estimation Using Screening Data
To facilitate eating disorder (ED) diagnosis, individuals usually undergo a brief screening before being referred for a full-scale diagnostic...
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Usefulness of UF-5000 automatic screening system in UTI diagnosis
We have evaluated the Sysmex UF-5000 cytometer use in microbiology for the screening of negative urines, looking for cut-off points to detect...
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Determining the optimal cut-off scores for the Chinese version of the Memorial Anxiety Scale for Prostate Cancer (MAX-PC)
PurposeAnxiety is a common emotion experienced by patients with prostate cancer (PCa), and can be exacerbated by testing the prostate-specific...
