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Biomarkers of Age-Related Frailty and Frailty Related to Diseases: An Exploratory, Cross-Sectional Analysis from the MAPT Study
BackgroundFrailty may in most cases result from two main causes: the aging process (age-related frailty) and diseases (evolving chronic conditions or...
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Association of age-related eye diseases with cognitive frailty in older adults: a population-based study
BackgroundAge-related eye diseases and cognitive frailty (CF) are both important predictors of adverse health outcomes in older adults, however,...
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Vaccines, Vaccine-Preventable Diseases, and Frailty
Infections have important adverse consequences for older adults, particularly those who are frail. In this chapter, we review how age and frailty... -
Frailty
The proportion of older people is continuously growing worldwide. This demographic phenomenon threatens the sustainability of our healthcare systems.... -
Dysphagia is closely related to frailty in mild-to-moderate Alzheimer’s disease
IntroductionPhysical phenotype and the cumulative deficit model are two well-known concepts of frailty. One of the main components of frailty is loss...
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Oral Health and Frailty
The mouth is a vital aspect of daily life, contributing to survival through eating and fostering social interaction via communication. Despite its... -
Frailty is related to serum inflammageing markers: results from the VITAL study
Frailty describes an age-associated state in individuals with an increased vulnerability and less resilience against adverse outcomes. To score...
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Biomarkers of Frailty
Several biomarkers have been proposed to identify the multisystemic age-related syndrome, frailty. However, due to its complex pathophysiology and... -
Assessing Frailty in Gastrointestinal Cancer: Two Diseases in One?
Purposeof ReviewThis review examines the challenges of treating gastrointestinal cancer in the aging population, focusing on the importance of...
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Physical frailty is related to oxidative stress through thiol/disulfide homeostasis parameters
AimTo evaluate relationship between frailty and oxidative stress through thiol/disulfide homeostasis parameters [Native thiol (NT), total thiol (TT),...
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Frailty
The proportion of older people is continuously growing worldwide. This demographic phenomenon threatens the sustainability of our healthcare systems.... -
Association of the triglyceride-glucose index and its related parameters with frailty
BackgroundFrailty is a dynamic geriatric condition. Limited studies have examined the association of the triglyceride-glucose (TyG) index and its...
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Frailty and Sarcopenia
Ageing, frailty, sarcopenia, falls, and fragility fractures are strongly linked and are predictors of reduction in physical function,... -
Self-Reported Oral Diseases and Their Association with the Frailty index among Older Japanese People: Four-Year Follow-Up
BackgroundOral health is a relevant component for overall health. Oral disease onset at an early age and may harm several health dimensions,...
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Frailty and Cardiovascular Disease
The population is aging, and the biology of aging is conducive to both the development of cardiovascular disease (CVD) as well as frailty, such that... -
Complications of Frailty
Regardless of the operational definition used, complications when facing common stressors are the main feature of frailty. A variety of these... -
Sex Differences and Frailty
Whether sex influences susceptibility to health deficits is well studied. The presence of sex differences in frailty is largely influenced by the... -
The Frailty Phenotype
The frailty phenotype framework, developed by Dr. Linda Fried and her team, marks a pivotal development in gras** the essence of frailty within the... -
Association between physical performance during sit-to-stand motion and frailty in older adults with cardiometabolic diseases: a cross-sectional, longitudinal study
BackgroundAlthough physical performance tests of the lower extremities are used to assess sarcopenia and frailty, little is known about the...