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Aspirin Intolerance
Disturbances of the arachidonic acid metabolism, resulting in a pathologic eicosanoid shift, represent a common pathway in the pathophysiologic...
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Allheilmittel Aspirin?
Wir wollen möglichst gesund sehr alt werden. Um das zu erreichen, folgen wir zum Teil recht alten medizinischen Ratschlägen. So schlucken Millionen...
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Aspirin® – das meistverwendete Arzneimittel in der Geschichte der Menschheit
Dieses Buchkapitel gibt einen umfassenden Überblick über die Geschichte und Entwicklung von Aspirin. Beginnend mit der Geschichte des Salix-Baumes...
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Thromboxane biosynthesis in cancer patients and its inhibition by aspirin: a sub-study of the Add-Aspirin trial
BackgroundPre-clinical models demonstrate that platelet activation is involved in the spread of malignancy. Ongoing clinical trials are assessing...
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Aspin: neurosurgical aspirin intervention prognostic study — perioperative continuation versus discontinuation of aspirin in lumbar spinal surgery, a randomized controlled, noninferiority trial
RationaleAspirin is typically discontinued in cranial and spinal surgery because of the increased risk of hemorrhagic complications, but comes...
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Using aspirin to prevent and treat cancer
This review will discuss evidence that aspirin possesses anticancer activity. Long-term observational retrospective studies on nurses and health...
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The Effects of Aspirin dose in Children with Congenital and Acquired Heart Disease. Results from the Paediatric Study of Aspirin Efficacy using Diagnostic and Monitoring Tools (PAED-M)
The optimal dose of aspirin required in children with congenital and acquired heart disease is not known. The primary aim of this prospective...
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Does an Aspirin a Day Take the MASLD Away?
Although aspirin is deeply rooted in the most ancient history of medicine, the mechanism of action of this drug was only identified a few decades...
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Aspirin and Plavix/Clopidogrel
This chapter reviews the neuroimaging features of the potential effects of aspirin.
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Missed opportunities in aspirin prescribing for preeclampsia prevention
BackgroundHypertensive disorders of pregnancy, including preeclampsia, are a leading cause of perinatal morbidity and mortality in the United States,...
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The Cost-Effectiveness of Rivaroxaban Plus Aspirin Compared with Aspirin Alone in the COMPASS Trial: A US Perspective
BackgroundRivaroxaban 2.5 mg twice daily with aspirin 100 mg daily was shown to be better than aspirin 100 mg daily for preventing cardiovascular...
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Inflammation, Frailty, and Aspirin Use in the Physicians’ Health Study: A Pilot Study
Whether anti-inflammatory medications such as aspirin can lower the risk of frailty is an active area of investigation. In previous studies, we...
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Aspirin inhibits rotavirus replication and alters rat gut microbial composition
BackgroundAspirin is widely used to treat various clinical symptoms. Evidence suggests that aspirin has antiviral properties, but little is known...
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The effect of low-dose aspirin on aspirin triggered lipoxin, interleukin 1 beta, and prostaglandin E2 levels in periapical fluid: a double-blind randomized clinical trial
BackgroundThe role of pro-resolving mediators in inflammation is a new concern in research. The effect of low-dose aspirin on production of a special...
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Aspirin as a chemopreventive agent for cutaneous melanoma: a literature review
Rising melanoma rates have spurred interest in preventive strategies. Nonsteroidal anti-inflammatory drugs (NSAIDs), particularly aspirin, show...
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Respiratory Exposure Tests in Aspirin Exacerbated Respiratory Disease
Purpose of reviewControlled oral provocation test with aspirin is considered the “gold standard” for diagnosing hypersensitivity to NSAIDs...
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Aspirin and cancer treatment: systematic reviews and meta-analyses of evidence: for and against
Aspirin as a possible treatment of cancer has been of increasing interest for over 50 years, but the balance of the risks and benefits remains a...
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Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition
BackgroundTo support proliferation and survival within a challenging microenvironment, cancer cells must reprogramme their metabolism. As such,...
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Aspirin use and head and neck cancer survival and recurrence
BackgroundHead and neck cancer (HNC) has low 5-year survival, and evidence-based recommendations for tertiary prevention are lacking. Aspirin...