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Dermatologic toxicities of anti-neoplastic immunotherapy in United States hospitalizations
A major side effect of anti-neoplastic immunotherapy is the onset of dermatologic toxicities following the administration of several different...
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Identification of potential oral cancer drugs as Bcl-2 inhibitors from known anti-neoplastic agents through docking studies
Oral Cancer is one of the major killers in India and of global concern. An attempt has been made here to identify small molecule inhibitors of Bcl-2...
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Development of a claims-based risk-scoring model to predict emergency department visits in older patients receiving anti-neoplastic therapy
This study developed and validated a risk-scoring model, with a particular emphasis on medication-related factors, to predict emergency department...
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Anti-coagulant Treatment of Cancer-Associated Thrombosis in Frail Patients: Impact of Frailties on the Management of Drug–Drug Interactions
Low molecular weight heparins (LMWH) and anti-Xa direct oral anti-coagulants (DOACs) are recommended for the long-term treatment of cancer-associated...
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Anti-neoplastic action of Cimetidine/Vitamin C on histamine and the PI3K/AKT/mTOR pathway in Ehrlich breast cancer
The main focus of our study is to assess the anti-cancer activity of cimetidine and vitamin C via combating the tumor supportive role of mast cell...
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Anti-neoplastic pharmacophore benzophenone-1 coumarin (BP-1C) targets JAK2 to induce apoptosis in lung cancer
Reigning of the abnormal gene activation associated with survival signalling in lung cancer leads to the anomalous growth and therapeutic failure....
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Psoriasis in the Era of Targeted Cancer Therapeutics: A Systematic Review on De Novo and Pre-existing Psoriasis in Oncologic Patients Treated with Emerging Anti-neoplastic Agents
New advancements in medicine have paved the way for targeted therapies and immune checkpoint inhibitors (ICIs), which have become mainstays of cancer...
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Association of inappropriate polypharmacy with emergency department visits in older patients receiving anti-neoplastic therapy: a population-based study
PurposeWe aimed to investigate the prevalence and predicting factors of inappropriate polypharmacy including potentially inappropriate medications...
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Drug Repurposing for Treatment of Cancer
Drug repurposing is a ray of hope for therapy of various diseases including cancer. Since historical times, drugs like nitrogen mustards,...
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Anti-neoplastic Immunomodulatory Treatments and the Pituitary
Immune checkpoint inhibitors (CPIs) have transformed the landscape of oncology since the approval of ipilimumab by the US Food and Drug...
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Drug Solubilization and Drug Release from Polymeric Micelles
Amphiphilic polymeric block copolymers find frequent applications due to their ability to deliver hydrophobic moieties to the physiological system....
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Nanotechnology in Drug Delivery
A biologically active substance (chemical compound, peptide, antibodies, gene-based drugs etc.) capable of producing a therapeutic effect can be...
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Adverse Drug Reactions
Adverse events and adverse drug reactions are common in clinical practice. Side effects range from the common to the rare and may be confused with...
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Cancer drug sensitivity prediction from routine histology images
Drug sensitivity prediction models can aid in personalising cancer therapy, biomarker discovery, and drug design. Such models require survival data...
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Drug Repurposing for Treatment of Cancer
Drug repurposing is a ray of hope for therapy of various diseases including cancer. Since historical times, drugs like nitrogen mustards,...
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Drug Repurposing for Hematological Malignancies
Hematological malignancies are cancer that affects blood, bone marrow, and lymph nodes. They are classified as leukemia, lymphoma, and myeloma based...
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Cancer Drug Resistance and Metabolic Reprogramming
There is a complex and strong association between metabolic reprogramming and the phenomenon of drug resistance in cancer. Cancer cell metabolic...
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Cell–drug conjugates
By combining living cells with therapeutics, cell–drug conjugates can potentiate the functions of both components, particularly for applications in...
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Prevalence and factors associated with potential drug-drug interactions in prescriptions presented at private pharmacies in Mbarara city, southwestern Uganda
BackgroundDrug-drug interactions (DDIs) influence the effectiveness of medication and thus determine the treatment outcomes of diseases managed with...
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Fabrication of folic acid-embedded aminated drug encapsulated zeolitic imidazolate framework as promising drug delivery system for lung cancer
A novel pH-responsive drug carrier for the delivery of specific Docetaxel (DTX) administration is developed based on a zeolitic imidazolate framework...
