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What is new in the classification of peripheral T cell lymphomas?
In this review focus article, we highlight the main modifications introduced in the latest 2022 International Consensus Classification and World...
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MicroRNA expression signature as a biomarker in the diagnosis of nodal T-cell lymphomas
BackgroundThe diagnosis of T-cell lymphomas is typically established through a multiparameter approach that combines clinical, morphologic,...
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Central Nervous System Relapse in T and NK cell Lymphomas
Purpose of ReviewT and NK cell lymphomas are relatively rare and heterogeneous forms of non-Hodgkin lymphoma that are associated with high rates of...
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Updates in the Classification of T-cell Lymphomas and Lymphoproliferative Disorders
Purpose of ReviewMature T/NK-cell neoplasms comprise a heterogeneous group of diseases with diverse clinical, histopathologic, immunophenotypic, and...
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Mature T-cell and NK-cell lymphomas: updates on molecular genetic features
Mature T-cell and NK-cell lymphomas are a heterogeneous group of rare and typically aggressive neoplasms. Diagnosis and subclassification have...
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Moving towards biologically informed treatment strategies for T-cell lymphomas
The rarity and biological heterogeneity of the peripheral T-cell lymphomas has made subtype- and biomarker-driven approaches challenging to realize...
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Extranodal T- and NK-cell lymphomas
Non-cutaneous extranodal NK/T cell lymphoproliferations constitute a heterogenous group of rare neoplasms, occurring primarily in the...
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Classification and diagnostic evaluation of nodal T- and NK-cell lymphomas
Nodal T- and NK-cell lymphomas are among the most frequent T-cell malignancies and most subtypes have aggressive clinical behavior. Evolving...
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Radiation Therapy in Peripheral T-Cell and Cutaneous Lymphomas
Peripheral T-cell lymphomas (PTCLs) represent ≤15% of new non-Hodgkin lymphoma cases. For accurate diagnosis of PTCL, an expert hematopathology...
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T Cell Malignancies
Malignant transformation of T lymphocytes can result in T cell leukemia or T cell lymphoma. Leukemias originate from immature T cells bone marrow...
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Duvelisib plus romidepsin in relapsed/refractory T cell lymphomas: a phase 1b/2a trial
PI3K-δ inhibitors have shown impressive activity in lymphoid malignancies but have been hampered by autoimmune and infectious toxicities, leading to...
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Bispecific antibodies and CAR-T cells: dueling immunotherapies for large B-cell lymphomas
Despite recent advances in frontline therapy for diffuse large B-cell lymphoma (DLBCL), at least a third of those diagnosed still will require second...
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Cytotoxic peripheral T-cell lymphomas and EBV-positive T/NK-cell lymphoproliferative diseases: emerging concepts, recent advances, and the putative role of clonal hematopoiesis. A report of the 2022 EA4HP/SH lymphoma workshop
Cytotoxic peripheral T-cell lymphomas and EBV-positive T/NK-cell lymphoproliferative diseases were discussed at the 2022 European Association for...
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Low T3 syndrome as a predictor of poor prognosis in peripheral T-cell lymphomas
PurposeThe purpose of the study was to evaluate the prognostic value of low T3 syndrome in peripheral T-cell lymphomas (PTCLs).
Methods ...
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How we treat NK/T-cell lymphomas
Natural killer (NK)/T-cell lymphomas are aggressive malignancies with a predilection for Asian and South American populations. Epstein–Barr virus...
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First-Line Therapy for Nodal T-cell Non-Hodgkin Lymphomas: an Unmet Need in Hematology
Purposeof ReviewThe main aim of this review is to summarize first-line therapy of nodal T-cell non-Hodgkin lymphoma.
Recent FindingsCurrent...
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Management of Peripheral T-cell Lymphomas and the Role of Transplant
Purpose of ReviewHere, we review the management of peripheral T-cell lymphoma, particularly focusing on the role of autologous and allogeneic stem...
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25-Hydroxy vitamin D deficiency is an inferior predictor of peripheral T-cell lymphomas
The aim of the study was to explore the significance and prognostic value of 25-hydroxy vitamin D (25-(OH) D) deficiency in peripheral T-cell...
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Follicular helper T-cell lymphomas: disease spectrum, relationship with clonal hematopoiesis, and mimics. A report of the 2022 EA4HP/SH lymphoma workshop
Follicular helper T-cell lymphomas (TFH lymphomas) were discussed in session V of the lymphoma workshop of the European Association for...
