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  1. Exploration of symptom clusters during hemodialysis and symptom network analysis of older maintenance hemodialysis patients: a cross-sectional study

    Background

    Symptom networks can provide empirical evidence for the development of personalized and precise symptom management strategies. However,...

    Mingyao Zhou, **aoxin Gu, ... Nina Zhang in BMC Nephrology
    Article Open access 27 April 2023
  2. The change of symptom clusters in gastric cancer patients during the perioperative period: a longitudinal study

    Aim and objectives

    The purpose of this study was to describe the number, type and trajectory of symptom clusters during the perioperative period in...

    Jianjian Wei, Hongxia Yan, ... Fang He in Supportive Care in Cancer
    Article 27 May 2024
  3. The Severity of Chronic Cough Diary (SCCD): development and content validation of a novel patient-reported outcome instrument for evaluating the symptom experience of chronic cough

    Background

    Refractory chronic cough (RCC), a cough lasting longer than 8 weeks with an unexplained underlying etiology and unresponsive to...

    Margarita de la Orden Abad, Claudia Haberland, ... Asha Hareendran in Journal of Patient-Reported Outcomes
    Article Open access 10 July 2023
  4. Children’s emotional reactivity and negative affect predict future ADHD symptom severity beyond initial ADHD symptom severity

    Children with Attention-Deficit/Hyperactivity Disorder (ADHD) often experience significant emotion dysregulation. However, there is limited...

    Helena F. Alacha, Paul J. Rosen, Sara J. Bufferd in European Child & Adolescent Psychiatry
    Article 19 March 2024
  5. Non-adherence, medication beliefs and symptom burden among patients receiving hemodialysis -a cross-sectional study

    Background

    Non-adherence to medication is a common and complex issue faced by individuals undergoing hemodialysis (HD). However, more knowledge is...

    Trine Mechta Nielsen, Trine Marott, ... Thordis Thomsen in BMC Nephrology
    Article Open access 27 October 2023
  6. Develo** a fit-for-purpose composite symptom score as a symptom burden endpoint for clinical trials in patients with malignant pleural mesothelioma

    We developed a composite symptom score (CSS) representing disease-related symptom burden over time in patients with malignant pleural mesothelioma...

    Charles S. Cleeland, Karen N. Keating, ... Tito R. Mendoza in Scientific Reports
    Article Open access 27 June 2024
  7. Improving symptom management for survivors of young adult cancer: rationale and study protocol for a pilot randomized controlled trial

    Background

    Young adult (YA) cancer survivors are a growing, yet underserved population who often face significant and long-lasting cancer-related...

    Caroline S. Dorfman, Rebecca A. Shelby, ... Kevin Oeffinger in Pilot and Feasibility Studies
    Article Open access 08 June 2024
  8. Evaluating the implementation and impact of navigator-supported remote symptom monitoring and management: a protocol for a hybrid type 2 clinical trial

    Background

    Symptoms in patients with advanced cancer are often inadequately captured during encounters with the healthcare team. Emerging evidence...

    Gabrielle B. Rocque, J. Nicholas Dionne-Odom, ... Jennifer Young Pierce in BMC Health Services Research
    Article Open access 22 April 2022
  9. Psychological distress mediates the association between COVID-19-related discrimination and subsequent PTSD symptom severity in healthcare workers: a two-year follow-up study

    Background

    Past research has suggested a cross-sectional association between COVID-19-related discrimination and PTSD symptom severity. However, no...

    Zui Narita, Ryo Okubo, ... Yoshiharu Kim in BMC Public Health
    Article Open access 09 July 2024
  10. Supporting primary care through symptom checking artificial intelligence: a study of patient and physician attitudes in Italian general practice

    Background

    Rapid advancements in artificial intelligence (AI) have led to the adoption of AI-driven symptom checkers in primary care. This study aimed...

    Angelika Mahlknecht, Adolf Engl, ... Christian Josef Wiedermann in BMC Primary Care
    Article Open access 04 September 2023
  11. “That’s just Future Medicine” - a qualitative study on users’ experiences of symptom checker apps

    Background

    Symptom checker apps (SCAs) are mobile or online applications for lay people that usually have two main functions: symptom analysis and...

    Regina Müller, Malte Klemmt, ... Robert Ranisch in BMC Medical Ethics
    Article Open access 16 February 2024
  12. Acceptability and experience of a smartphone symptom monitoring app for people with psychosis in China (You**n): a qualitative study

    Background

    Access to high-quality mental healthcare remains challenging for people with psychosis globally, including China. Smartphone-based symptom...

    **aolong Zhang, Shôn Lewis, ... Sandra Bucci in BMC Psychiatry
    Article Open access 09 April 2024
  13. Association of temporal discounting with transdiagnostic symptom dimensions

    Temporal discounting (TD), the tendency to devalue future rewards as a function of delay until receipt, is aberrant in many mental disorders....

    Kristof Keidel, ** Lu, ... Ulrich Ettinger in npj Mental Health Research
    Article Open access 16 April 2024
  14. Symptom burden and follow-up of patients with neck and back complaints in specialized outpatient care: a national register study

    Back and neck pain are common in the population, especially among immigrants. In Norway's specialist care system, treating these patients typically...

    John Bjørneboe, Andrea Bratsberg, ... Cecilie Røe in Scientific Reports
    Article Open access 15 February 2024
  15. Cow’s Milk-related Symptom Score (CoMiSS) values in presumed healthy European infants aged 6–12 months: a cross-sectional study

    The Cow’s Milk-related Symptom Score (CoMiSS) is an awareness tool for evaluating cow’s milk-related symptoms. Previous studies have focused on...

    Mateusz Jankiewicz, Fatme Ahmed, ... Hania Szajewska in European Journal of Pediatrics
    Article Open access 17 November 2023
  16. Multi-symptom Relief with Propylene Glycol-Hydroxypropyl-Guar Nanoemulsion Lubricant Eye Drops in Subjects with Dry Eye Disease: A Post-Marketing Prospective Study

    Introduction

    The study aimed to evaluate multi-symptom relief of dry eye manifestations with the use of propylene glycol-hydroxypropyl-guar (PG-HPG)...

    Katherine Bickle, Jason R. Miller, ... Deborah Awisi-Gyau in Ophthalmology and Therapy
    Article Open access 11 December 2023
  17. Symptom Trajectories Informing Patient Care After Lung Cancer Surgery: A Longitudinal Patient-Reported Outcome Study

    Background

    Application of patient-reported outcomes (PROs) in surgical oncology has been limited because of patient heterogeneity. We analyzed symptom...

    Li Tang, Hongfan Yu, ... Qiuling Shi in Annals of Surgical Oncology
    Article 19 January 2023
  18. Feasibility, acceptability, and outcome responsiveness of the SYMPERHEART intervention to support symptom perception in persons with heart failure and their informal caregivers: a feasibility quasi-experimental study

    Background

    Symptom perception is an important process of heart failure (HF) self-care that persons with HF need in order to master self-care...

    Gabrielle Cécile Santos, Maria Liljeroos, ... Petra Schäfer-Keller in Pilot and Feasibility Studies
    Article Open access 04 October 2023
  19. Contemporaneous Symptom Networks of Breast Cancer-Related Upper Limb Lymphedema: A Network Analysis

    Background

    Upper limb lymphedema (ULL) is a common and deliberating complication for breast cancer survivors (BCSs). Breast cancer survivors with ULL...

    Aomei Shen, Wanmin Qiang, ... Qian Lu in Annals of Surgical Oncology
    Article 03 July 2024
  20. Symptom presentation by phenotype of postural orthostatic tachycardia syndrome

    Postural orthostatic tachycardia syndrome (POTS) presents heterogeneously and is diagnosed when appropriate symptoms are present in conjunction with...

    Allison M. Angeli, Bradley R. Salonen, ... Christopher Aakre in Scientific Reports
    Article Open access 02 January 2024
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