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Cryopreserved cGMP-compliant human pluripotent stem cell-derived hepatic progenitors rescue mice from acute liver failure through rapid paracrine effects on liver cells
BackgroundLiver transplantation remains the only curative treatment for end-stage liver diseases. Unfortunately, there is a drastic organ donor...
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Hematopoietic Stem Cell Transplantation
Since the start of the international stem cell programme for autoimmune diseases in 1997, 3855 stem cell transplants for autoimmune disease have been...
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Indications for Autologous Stem Cell Transplant
Autologous stem cell transplant (auto SCT) is a procedure where stem cells are mobilized and harvested and then the patient is treated with high-dose...
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PD-1 blockade immunotherapy as a successful rescue treatment for disseminated adenovirus infection after allogeneic hematopoietic stem cell transplantation
Disseminated adenovirus infection is a complication with a relatively high mortality rate among patients undergoing hematopoietic stem cell...
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High-dose chemotherapy with stem cell rescue to treat stage III homologous deficient breast cancer: factors influencing clinical implementation
BackgroundHigh-dose chemotherapy with autologous stem cell rescue (HDCT) is a promising treatment for patients with stage III, HER2-negative,...
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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Differential requirements for Smarca5 expression during hematopoietic stem cell commitment
The formation of hematopoietic cells relies on the chromatin remodeling activities of ISWI ATPase SMARCA5 (SNF2H) and its complexes. The Smarca5 null...
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Neural Stem Cell Intervention in Traumatic Brain Injury
Introduction: Traumatic brain injury (TBI)Traumatic Brain Injury (TBI) is a major cause of death and disability worldwide. The secondary brain damage...
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Basics of Stem Cell Transplant
Hematopoietic stem cell transplantation (SCT) is a procedure where the blood-forming stem cells of a donor are given to a recipient with the...
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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The 3' end of the coding region of senecavirus A contains a highly conserved sequence that potentially forms a stem-loop structure required for virus rescue
Senecavirus A (SVA) can cause a vesicular disease in swine. It is a positive-strand RNA virus belonging to the genus Senecavirus in the family Picornaviridae...
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Stem Cell Clinical Trials and Stem Cell Market
Stem cell therapy requires the usage of stem cells for prevention or treatment of a disease or condition. Stem cell therapies are under investigation...
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Clinical applications of stem cell-derived exosomes
Although stem cell-based therapy has demonstrated considerable potential to manage certain diseases more successfully than conventional surgery, it...
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Drugs Used Post stem Cell Transplant
Various drugs are used in the treatment of patients with hematological malignancies and during stem cell transplant (SCT) including steroids,...
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Stem Cell Transplant for B Cell Non-Hodgkin Lymphoma
Non-Hodgkin Lymphoma (NHL) can be divided into B cell NHL and T cell NHL. B cell NHL is more common than T cell NHL. Most of the B cell NHLs are...
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Strategies to Upgrade the Stem Cell Application for Brain Transplantation
Introduction: Cerebral stem cellStem cell transplantation has the potential to replace dead cells and restore lost brain functions in...
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Stem cell models of inherited arrhythmias
Inherited arrhythmias are a heterogeneous group of conditions that confer risk of sudden death. Many inherited arrhythmias have been linked to...
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Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression
BackgroundSpermatogonial stem cells (SSCs) provide a foundation for robust and continual spermatogenesis in mammals. SSCs self-renew to maintain a...
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Stem Cell Culture and Its Applications
Cells are the structural and functional unit of life. The dynamics of life encompass the continuous interaction of the cells with the environment and...