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Sodium Butyrate Induced Neural Stem/Progenitor Cell Death in an Experimental Model of Japanese Encephalitis
The anti-inflammatory and neuroprotective effects of short chain fatty acid (SCFA) butyrate have been explored in a wide array of neurological...
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Sodium butyrate exerts a neuroprotective effect in rats with acute carbon monoxide poisoning by activating autophagy through the mTOR signaling pathway
Acute carbon monoxide (CO) poisoning is a prevalent type of poisoning that causes significant harm globally. Delayed encephalopathy after acute...
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Effect and Mechanism of Sodium Butyrate on Neuronal Recovery and Prognosis in Diabetic Stroke
Ischemic stroke is a cerebrovascular lesion caused by local ischemia and hypoxia. Diabetes mellitus (DM) is a chronic inflammatory disease that...
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Modulation of GABA by sodium butyrate ameliorates hypothalamic inflammation in experimental model of PCOS
Polycystic ovarian syndrome (PCOS) is a known endocrine disorder that has affected many women of childbearing age, and is accompanied by various...
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Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids
BackgroundDiabetic retinopathy (DR) development is associated with disturbances in the gut microbiota and related metabolites. Butyric acid is one of...
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Autolyzed yeast and sodium butyrate supplemented alone to diets promoted improvements in performance, intestinal health and nutrient transporter in weaned piglets
This study investigated the effects of supplemental nucleotides, autolyzed yeast ( Saccharomyces cerevisiae ), and sodium butyrate in diets for nursery...
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Sodium Butyrate Ameliorates Fluorosis-Induced Neurotoxicity by Regulating Hippocampal Glycolysis In Vivo
Fluorosis can induce neurotoxicity. Sodium butyrate (SB), a histone deacetylase inhibitor, has important research potential in correcting glucose...
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Sodium Butyrate Inhibits the Malignant Proliferation of Colon Cancer Cells via the miR-183/DNAJB4 Axis
Colorectal carcinoma (CRC) is one of the most common malignant tumors in the digestive tract. It was found that butyric acid could inhibit the...
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Sodium butyrate alleviates R97-116 peptide-induced myasthenia gravis in mice by improving the gut microbiota and modulating immune response
Fermented butyrate exhibits an anti-inflammatory response to maintain immune homeostasis within the gut. However, the effect and underlying mechanism...
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Sodium Butyrate Ameliorates Atopic Dermatitis-Induced Inflammation by Inhibiting HDAC3-Mediated STAT1 and NF-κB Pathway
A topic dermatitis (AD) is a common chronic and recurrent skin disorder. The protective effects of sodium butyrate (NaB), a metabolite of short-chain...
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Sodium butyrate attenuates aortic lipotoxicity and impaired nitric oxide synthesis in female Wistar rats exposed to high-fructose drink
High fructose (HFr) intake results in dyslipidemia with consequent insulin resistance through metabolic derangements. Inadequate mobilization of...
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Dietary sodium acetate and sodium butyrate improve high-carbohydrate diet utilization by regulating gut microbiota, liver lipid metabolism, oxidative stress, and inflammation in largemouth bass (Micropterus salmoides)
BackgroundAdequate level of carbohydrates in aquafeeds help to conserve protein and reduce cost. However, studies have indicated that...
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Enhancing effect of sodium butyrate on phosphatidylserine–liposome-induced macrophage polarization
ObjectPhosphatidylserine-containing liposomes (PSLs) can mimic the immunomodulatory effects of apoptotic cells by binding to the phosphatidylserine...
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Influence of histone deacetylases inhibitor sodium butyrate on hippocampal neuronal activity in vivo
Epigenetic regulation plays an important role in cognitive brain functions. The increase in histone acetylation by histone deacetylase inhibitors,...
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Sodium butyrate induces ferroptosis in endometrial cancer cells via the RBM3/SLC7A11 axis
Ferroptosis is a form of programmed cell death with important biological functions in the progression of various diseases, and targeting ferroptosis...
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Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation
Ketone bodies have beneficial metabolic activities, and the induction of plasma ketone bodies is a health promotion strategy. Dietary supplementation...
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Chronic radiation proctitis refractory to steroid enema was successfully treated by metformin and sodium butyrate: a case report
BackgroundRadiation proctitis (RP) is a significant complication of pelvic radiation. Effective treatments for chronic RP are currently lacking. We...
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Sodium Acetate and Sodium Butyrate Differentially Upregulate Antimicrobial Component Production in Mammary Glands of Lactating Goats
Short-chain fatty acids activate antimicrobial component production in the intestine. However, their effects on mammary glands remain unclear. We...
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Sodium butyrate inhibits osteogenesis in human periodontal ligament stem cells by suppressing smad1 expression
BackgroundButyrate is a major subgingival microbial metabolite that is closely related to periodontal disease. It affects the proliferation and...
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Butyrate and tributyrin reduce LPS-induced inflammatory cytokine production from human visceral fat
IntroductionThe current obesity crisis has resulted in many people with excess adipose tissue suffering from chronic inflammation. This inflammation...
